Top 10 Enterprise Software Startup Investors in Italy (May 2026)

Portfolio highlights

• Edison Spa — Edison is Europe's oldest energy company, and one of the industry leaders in Italy and Europe. Discover all the activities we ar
• Goglio Group — Goglio Group produces full trademark food packaging.
• Casalasco Società Agricola — Casalasco Società Agricola is the supply network for the cultivation and processing of industrial tomatoes.

Portfolio highlights

• THRON — Siamo THRON. Quelli della piattaforma unica per governare insieme asset digitali e dati di prodotto, distribuendoli su tutti i tuoi canali di comunicazione.

Portfolio highlights

• Picosats — PicoSaTs envisages a new generation of telecommunication systems for space applications dedicated to CubeSat pico-satellites. The key technologies at the core of this system are a software defined radio and a highly directive and configurable antenna, operating at higher frequencies (Ka band), and providing very high data rates.
• Leaf Space — Leaf Space aims to become a global leading service provider in the new, emerging microsatellite market by developing a technology platform providing all basic services required by microsatellite operators.
• Energy Dome — Energy Dome | Groundbreaking Long Duration Energy Storage. Using CO2 against climate change. Our Technology enables to store renewable energy efficiently.

Portfolio highlights

• GHOSTDRIVE — The Ghostdrive leverages the decentralized nature of P2P networks (IPFS, and Filecoin) to provide unlimited data uploads. Unlike traditional centralized systems, where storage capacity is finite, P2P networks can dynamically expand their storage capabilities as more users join the network.
• Flanksource — Mission Control for Enterprise Software Teams
• SEO Site Checkup — SEO Site Checkup offers webmasters, small business owners, and SEO agencies with SEO tools, software, and articles. It offers users with analysis and monitoring tools to analyze SEO issues of websites, to generate white-label SEO reports, to receive notifications on SEO score changes, and to understand their competitors’ SEO profiles.SEO SiteCheckup is operated from New York, United States.

Portfolio highlights

• THRON — THRON is a software-as-a-service solution that allows you to unify all content-related processes in your company, centralizing and organizing all products and digital assets (images, video, pdfs, documents, web pages); deliver content within your organization and across your online channels at the highest quality; personalize communication throughArtificial Intelligence, which profiles users based on the content they have viewed.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• Crea — CREA is the leading digital commerce enabler providing end to end solution for brands to reach the booming, digital savvy millennial and Generation Z consumers in Southeast Asia.
• AGORA — Discover what we are known best for, our AGORA Edits!
• ZAGO Milano — La tua skincare e skin-prep Made in Italy con Amore!

Portfolio highlights

• Foxwin — Foxwin is an information technology company that helps companies engage their employees. It provides consultancy service to transform innovation, usually an occasional activity, into an ongoing process. It also specializes in the fields of Idea management platform, employee engagement, and employee suggestion systems.The company was founded in2016 and headquartered in Friuli-Venezia Giulia, Italy.
• Poetronicart — Poetronicart is a technological platform which enhance and create opportunity for artistic work and projects.

Portfolio highlights

• KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.