Top 10 CleanTech Startup Investors in Italy (May 2026)

Portfolio highlights

• Picosats — PicoSaTs envisages a new generation of telecommunication systems for space applications dedicated to CubeSat pico-satellites. The key technologies at the core of this system are a software defined radio and a highly directive and configurable antenna, operating at higher frequencies (Ka band), and providing very high data rates.
• Leaf Space — Leaf Space aims to become a global leading service provider in the new, emerging microsatellite market by developing a technology platform providing all basic services required by microsatellite operators.
• Energy Dome — Energy Dome | Groundbreaking Long Duration Energy Storage. Using CO2 against climate change. Our Technology enables to store renewable energy efficiently.

Portfolio highlights

• Scuter — NEXT GEN SHARING MOBILITY Introducing the ultimate sharing mobility service, designed to be much better than all the rest. The all-new website. Available so ...
• Newarc srl — With the help of technology, we simplify and improve the home buying and selling process.
• Green Independence — Green Independence is a startup committed in developing disruptive energy technology solutions, gradually leading the transition to a sustainable zero-emission-world powered by renewable sources. Our main technology is the New Artificial Leaf (NAL). NAL is a new technology that is able to efficiently store solar energy into chemical bonds,similarly to what happens in natural photosynthesis, converting water, CO2 and many other waste products. Currently, its main products are Green Hydrogen and Syngas (H2 + CO). NAL can guide the conversion of current energy production plants into low / zero emissions power-plants, without dismissing the current infrastructure.

Portfolio highlights

• Tame — ABOUT With Tame you can fully customise your virtual events, and make them fun, engaging & exciting to attend.- Apply your branding: Customise your virtual event completely - Personalised Welcome: Personal welcome message when attendees enter - Multiple stages: Broadcast content across multiple stages. - Live streaming: Stream live via anybroadcasting software - Pre-recorded videos: Broadcast pre-recorded videos as if it was live - Breakout sessions: Enable public or private breakout sessions. - Virtual Sponsor booths: Allow attendees to engage with sponsors live. - Customise Chat: Allow for 1:1 chat, group chat or session chat. - 1:1 Video Meetings: Empower social networking virtually.OUR COMPANY We are an experience-centric company, and we believe in the power of great experiences. 
 Our international group of dreamers, creators and rule-breakers passionate about merging design and technology together, enables us to transform that into one truly amazing event platform.OUR PEOPLE The team behind Tame has an aggregated decades long experience of creating events and building products that solve real problems for real people. So, what got us here? Our ambition to change a broken event industry through innovation, customer obsession and a relentless focus on the great experience.
• Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime

Portfolio highlights

• CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.
• Test1 soultions — Test1 Solutions is an oil absorbent technique for hydrocarbons and their derivatives. They serve environmental clean up, oil spill clean up, hydrocarbon spills, geennovation, open cell oleophilic polyurethane foam with a hydrophobic effect, and hydrocarbon spills on water and land.
• Comptek Solutions — Comptek Solutions' novel passivation technology - Kontrox - promotes surface crystalline oxide reconstructions on the surface of the III-V compound semiconductor materials, enabling unprecedented efficiency of devices and a significant reduction in manufacturing costs

Portfolio highlights

• Largix — Largix is the first company to develop and commercially produce 3D Robotic Printers for real production processes. We have invented the "Cold 3D Printing®" technology that makes 3DP possible for real industrial production. Largix uses the most common thermoplastic polymers: Polypropylene and Polyethylene, polymers that nobody else iscapable of printing.
• TextYess — Increase your eCommerce Retention with a Frictionless Experience.
• Electra Vehicles — Control, Analyze, & Design Innovative Battery Packs using Electra Vehicles' EVE-Ai 360 Adaptive Controls and Analytics and EnPower Design.

Portfolio highlights

• Pixies — Pixies is a Startup that design solutions for Autonomous Cities and a more sustainable future of our planet. Merging Urban Design, Robotics and AI, we believe that urban spaces can now become able to take care of themselves.
• Alokino Gelato — Alokino Gelato produces plant-based and preservative-less artisanal ice creams.
• Nimai Digital Company — Think. Create. Make it happen.

Portfolio highlights

• Wiseair — Wiseair's mission is to enable everyone in the world to breathe clean air. We believe that a problem you can't measure is a problem you can't solve, so we work to enable municipalities, citizens and businesses to measure and learn about air quality, creating actionable, solution-oriented data and information, and generatingawareness.
• Energy Dome — Energy Dome | Groundbreaking Long Duration Energy Storage. Using CO2 against climate change. Our Technology enables to store renewable energy efficiently.

Portfolio highlights

• Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
• Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
• Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Portfolio highlights

• CyLock — CyLock anti-hacker is a software designed to defend systems from hacker attacks, identifying weaknesses in their systems and websites, and providing information to address vulnerabilities used by the cybercriminal to access their computers. Through CyLock's Anti-Hacker system, small and medium-sized businesses will be able to test theirdigital defences to identify and eliminate vulnerabilities in websites, e-commerce sites, apps, e-mails, information systems, corporate networks, servers, and IoT. Companies that do not periodically test their digital tools and their staff skills are more exposed to cyber attacks, which turn into business interruptions, document loss, e-commerce, and online payments breakdown.
• Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
• Rocky — Grow your mindset with the AI coaching chat in just 5 minutes of daily self-improvement sessions to be truly successful.

Portfolio highlights

• i-TES srl — i-TES is providing consulting and assistance. They reduce energy waste and optimism the management of the system with the i-TES PCM thermal coil. They provide services for the thermal accumulator, including assistance, maintenance, consulting, research, and development. They provide research and development activities in the field of thermalstorage with innovative materials.
• Planckian — Charging the future by powering energy with science We explore frontiers of energy science by developing quantum...
• BeDimensional — We produce graphene and others two-dimensional materials (2D) with few atomic layers. Find out more.