Top 50 Medical Device VC (Venture Capital) Funds in United States in October 2023

Portfolio highlights

• Isomark Health — Isomark Health is a patented AI-based, real-time and 100% green breath technology that detects and prevents bacterial and viral infections.
• Rantizo — Rantizo provides drone spraying systems and support services for custom applicators, agribusinesses and contractors. Elevating precision ag.
• Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.

Portfolio highlights

• Nyra Medical — MitraPlug has created a catheter-plug technology for repairing a leaky mitral valve in the heart.This adjustable device needs only a two-inch surgical incision and can be inserted directly into the heart. Then the cardiologist can use the catheter to adjust the size and position of the plug to correct the leakage. When correctly fitted, thecatheter is removed, and the incision is closed, leaving only a small scar.
• RapidPulse — RapidPulse, Inc. is a privately held medical device company that develops minimally invasive vascular products for ischemic stroke. The company is advancing the development of the RapidPulse™ Cyclic Aspiration System, which includes a novel aspiration pump to allow rapid and consistent removal of blood clots from the brain. RapidPulse is a spinoutof Syntheon LLC., a medical device incubator dedicated to developing innovative products in the medical device industry
• Cardiosense — Cardiosense offers a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease. Its platform leverages multi-modal sensors and industry-leading AI to develop predictive biomarkers for the detection and treatment of disease.

Portfolio highlights

• Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
• Prime Roots — Prime Roots is on a mission to provide a better cut of meat for every type of eater. Rooted in koji, Prime Roots is able to replicate the taste and texture of meat without any of the environmental costs of animal proteins.
• Carbice Corporation — Carbice is the first no-compromise thermal interface material. It achieves all the advantages of both solid and liquid thermal interface materials without any of the pitfalls.

Portfolio highlights

• OOVA — OOVA is a fertility diagnostic company that spun out from Mount Sinai Hospital in New York City. Using patent pending biochemistry and artificial intelligence, OOVA learns a woman’s fertility profile by accurately measuring key hormones over time through daily urine samples. By monitoring this critical balance of hormones, OOVA can help a woman getpregnant, identify reasons she is having trouble getting pregnant, and even expose reproductive health issues like PCOS.
• Raise Green — Raise Green is the climate tech marketplace for local impact investing licensed with the SEC and FINRA to sell private securities.
• Driver Technologies — Turn your phone into a dash cam.

Portfolio highlights

• Amify — We help brands selling on Amazon maximize sales and profitability by providing complete strategy, management and operational services.
• Tembo — CoreDB provides a fully-managed, secure, scalable Postgres cluster with access to an ecosystem of extensions, expanding the capabilities of your database.
• Voxel — Voxel utilizes advanced mathematics and artificial intelligence to rapidly generate functionally graded meta-materials for high performance applications through additive manufacturing. We provides performance leaps in the defence, automotive, aerospace, medical, industrial, and other demanding areas and unlock new capabilities for our customers.

Portfolio highlights

• Agile Therapeutics — Agile Therapeutics, Inc., a specialty pharmaceutical company, engages in the development of women's healthcare products. It offers a low estrogen dose seven-day transdermal contraceptive patch system that delivers a combination of levonorgestrel and Ethinylestradiol. The company was founded in 1997 as Levotech, Inc. and changed its name toAgile Therapeutics, Inc. in April 2001. It is based in Princeton, New Jersey.
• GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
• Wavely Diagnostics — Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.

Portfolio highlights

• Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
• SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
• Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Portfolio highlights

• UnifyWork — UnifyWork's skills-based matching technology creates a faster way for employers to hire qualified talent, and helps job seekers find job opportunities meeting their skills and interests.
• Bloomfilter — Bloomfilter is a developer of an enterprise software planning application. Bloomfilter helps software executives and leaders illuminate the path to software project success through our platform.
• Vytalize Health — Vytalize Health is an all-in-one solution for independent primary care physicians participating in value-based care with Medicare. Vytalize integrates with physicians through people, technology, and unique value-based arrangements that result in better patient outcomes and better optimized care delivery.As of 2021, the company has 600+ PCPs,65K Medicare patients, and $1B in medical spending.

Portfolio highlights

• Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
• Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
• Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Portfolio highlights

• Renibus Therapeutics — Renibus Therapeutics operates in the healthcare industry focusing on the pharmaceutical business. The company was incorporated in 2015 and is based in Lantana, Texas.
• ALX Oncology — ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer. It is an independent, private biotechnology company.The founding of Alexo Therapeutics was based upon technology invented by Aaron Ring, K. Christopher Garcia, Kipp Weiskopf, Aron Levin, and Irving Weissman at Stanford University.This discovery involves soluble versions of signal regulatory protein-α (SIRPα) that have been engineered to bind CD47 with significantly greater affinity than natural SIRPα.1.
• Pearl Street Dental Management — Pearl Street Dental Management supports non-clinical operations. They provide centralized services such as human resources, payroll, accounting, bookkeeping, finance, lending, facilities management, and information technology services. They address inquiries through online applications, phone calls, and emails.

Portfolio highlights

• Flourish Collective — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
• Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
• Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.

Portfolio highlights

• HighByte — HighByte is an industrial software development company in Portland, Maine building solutions that address the data architecture and security challenges created by Industry 4.0.
• TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
• Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Portfolio highlights

• Pryon — Pryon is the leading AI-as-a-Service platform for content and knowledge management. Pryon closes knowledge gaps, improving employee productivity, and enhancing customer experiences. Companies such as Georgia Pacific use Pryon to improve health and safety outcomes, eliminate compliance incidents, improve employee onboarding, and upgrade all aspectsof customer service and support.
• VenoStent — VenoStent is a clinical-stage tissue engineering company that’s developed tunable, bioabsorbable smart polymer wraps in order to fundamentally transform the 5 million vascular surgeries performed each year.
• Lemurian Labs — Lemurian Labs develops disruptive, highly parallel, ultra low-power inner-product architecture to make deep learning and computer vision applications on the edge, sustainable, resulting in higher inference throughput, a reduction in energy consumed and a decrease in heat generated from chip processing

Portfolio highlights

• 32Co — 32Co is a medical technology platform that helps general dentists deliver clear aligner orthodontics to their patients.
• Essenvia — Rapidly submit eSTAR, EUMDR and IVDR applications, eliminate errors and accelerate approvals with the only regulatory submission platform made for MedTech
• Gradient Health — One of the biggest barriers to accelerating AI development is access to large datasets of labeled pathologies.

Portfolio highlights

• Sequoir — Sequoir is a financial technology firm providing blockchain trading and custody APIs to power banks, credit unions, fintech, and the Web 3.0.
• Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
• Nurse Disrupted — A virtual nursing program that retains nurses & improves hospital finances. Live in 4 weeks. Engaged, happier nurses in days.

Portfolio highlights

• Hopr — Hopr recognizes the increasing relevance of cybersecurity in today's global digital society. Hopr objective is to assist organizations in protecting their digital operations and data by rethinking old challenges and then developing innovative cybersecurity solutions to tackle them.
• Fem Equity — Fem Equity is a work platform that develops real-time solutions for women and underrepresented professionals experiencing salary or professional inequalities.
• N5 Sensors — Sensors and solutions for protecting lives and infrastructure from environmental hazards.

Portfolio highlights

• BrightSpec — LabBrightSpec addresses high-value, time-sensitive analytical chemistry challenges that are not well addressed by other spectroscopy techniques and instruments. It provides innovative laboratory services in order to deliver immediate results to potential customers of our instrumentation products. They are based in Charlottesville, Virginia,about two hours from Washington, DC. The BrightSpec Fourier transform molecular rotational resonance (FT-MRR) product platform is based on technology developed at the University of Virginia by Brooks Pate and his team, several of whom now work at BrightSpec. They offer FT-MRR product configurations for analytical chemistry and gas sensing in manufacturing process control, quality control, environmental monitoring, and formulation research.
• Boomerang Medical — Boomerang Medical is a bioelectronic medicine company targeting autoimmune diseases.
• Enumera Molecular — Enumera Molecular is a life science tools company headquartered in Ann Arbor, MI, developing a scalable biomolecule assessment platform enabling lower-cost, rapid clinical liquid biopsy tests. It helps in transforming the field of clinical molecular testing into a simpler, more actionable tool for physicians to benefit patient care.

Portfolio highlights

• Unagi Scooters — Unagi is an electric scooter startup that aims to liberate people from the tyranny of transportation frustrations—the costs, inconveniences, the carbon emissions. So we built the ideal personal liberation device.
• Evelo Biosciences — Evelo Biosciences is dedicated to improving the lives of patients globally through the development of a new modality of medicines – monoclonal microbials. Monoclonal microbials are orally delivered medicines that modulate systemic immunology and biology through direct interactions with human cells in the gut. These new medicines are broadlyapplicable across many diseases – including autoimmune, immunoinflammatory, metabolic, neurological, neuroinflammatory diseases and cancer. Monoclonal microbials have the potential to fundamentally change traditional models of drug discovery and development. By finding and selecting naturally occurring monoclonal microbials with defined therapeutic effects, Evelo can improve the speed, cost and success of drug discovery and development. Evelo’s platform enables pharmacological intervention at all stages of disease with naturally occurring, safe and effective monoclonal microbials. Evelo Biosciences was conceived and created within VentureLabs®, Flagship Pioneering’s institutional innovation foundry, and launched by Flagship in 2015.
• Slingshot Aerospace — Slingshot Aerospace applies advanced analytics, machine learning, and collaborative tools to data from earth and space, providing clarity in complex environments.

Portfolio highlights

• Yellowdig — Yellowdig offers educators a gameful learning digital solution to improve student engagement by building learning communities.
• ImpactableX — The social impact modeling & management toolkit behind leading solutions to our world's most pressing challenges.
• GrowFlux — GrowFlux, Inc. they offers a ecosystem of commercial scale wireless lighting controls, cloud services, and cloud connected agricultural sensors.

Portfolio highlights

• Paperspace — Ceres, Inc. (Ceres) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks. The Company’s large-scale commercial products are sweet sorghum varieties that can be used as a drop-in feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills. Its products include sweet sorghum, high biomasssorghum, switchgrass, miscanthus and row crops. Its energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Baseload utility scale electric power can also be generated from the biomass feedstocks grown from its seeds. Ceres has sold switchgrass and high biomass sorghum seeds in the United States under its Blade Energy Crops (Blade) brand. In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda.
• CardioFocus — CardioFocus provides electrophysiologists with innovative and effective tools that bring precision and control to the treatment of atrial fibrillation.
• Yolia Health — Yolia Health developed The True Vision Treatment or TVT, the 'Invisalign' for the eyes. A non-invasive treatment to correct vision problems like presbyopia without surgery. TVT is self-administered by the patient in his or her own home. It employs a combination of customized contact lenses (TVT Contacts) and specially formulatedeye drops (TVT Eye Drops). After only 5 days of treatment with TVT patients are able to stop using the TVT Contacts, TVT Eye Drops and their reading glasses for up to 12 months at a time before re-treatment with TVT is needed. What is even greater than correcting for presbyopia non-invasively, is correcting both eyes without compromising any distance vision. On the contrary, Yolia's treatment improves both near and distance vision, a unique feature no single other alternative can provide. ** Looking for sophisticated investors and key industry partners.

Portfolio highlights

• Percepto — Percepto is a developer of autonomous drone technology for inspection and surveillance.Drones hold the potential to disrupt multi-billion dollar industries including energy, security, insurance, agriculture, and more. Drones completely change the way inspection, measurement, surveillance, and deliveries are done today. Still, the main barrier tomaking them a must-have platform is the ability of drones to perform tasks autonomously.The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data.Leveraging its experience with Percepto Sparrow, the most deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring) the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.
• Trust Lab — Trust Lab develops solutions to detect and mitigate online safety threats and works with social media companies, advocacy groups, and other interested parties to implement them. Palo Alto, California, U.S.A.
• Luminopia — Luminopia is pioneering a new class of treatments for significant neuro-visual disorders. Luminopia is committed to creating digital therapeutics that are both rigorously evaluated for FDA approval and genuinely engaging for patients. As an Innovation Partner of Boston Children’s Hospital, the company is developing its lead product, Luminopia One,to treat amblyopia, the leading cause of vision loss among children. For more information, visit luminopia.com.

Portfolio highlights

• CellFE — CellFE is a company developing a microfluidics based device to deliver gene-editing molecules. CellFE developed microfluidic device and process that can efficiently deliver gene-editing molecules into the human cells.
• rabbit — Revolutionizing human-machine interaction
• Vayu Robotics — Vayu Robotics is an AI robotics company that develops and commercializes automotive sensing, autonomous vehicles, and robotics technology.

Portfolio highlights

• Rejoni — Rejoni uses bio-materials to develop medical devices that improve the outcome of minimally invasive and gynecological surgical procedures.
• Instylla — Instylla delivers next-generation liquid embolics for interventional radiology, with initial clinical applications in interventional oncology and peripheral hemostasis.
• Avive Solutions — Check out Avive Solutions, the manufacturers of a brand new AED machine - portable defibrillator - that's FDA approved!

Portfolio highlights

• Acesion Pharma — Acesion Pharma ApS is a Danish biotech company founded in 2011 and based in Copenhagen. Acesion Pharma develops more efficacious and safe drugs for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia.
• Actio Biosciences — At Actio, we are leveraging advances in genetics and precision medicine to develop life-changing treatments that target underlying shared biology between rare and common diseases. We are applying expertise in genetics, drug discovery, and data sciences to pinpoint targets that not only cause rare diseases with high unmet need, but that also hold promise in more common indications.
• Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.

Portfolio highlights

• Epitel — Epilog is an unobtrusive wearable seizure detection system that records long-term EEG, anywhere. It gives people living with epilepsy peace of mind with a much-needed tool to better understand and manage their seizures.
• Avive Solutions — Check out Avive Solutions, the manufacturers of a brand new AED machine - portable defibrillator - that's FDA approved!
• PanTher Therapeutics — PanTher Therapeutics is on a mission to revolutionize cancer care with a proprietary treatment platform designed to enhance therapeutic response with minimal side effects. PanTher’s highly adaptable platform empowers oncologists to treat patients with life-threatening cancer by unlocking a drug’s full potential through direct, sustained treatmentat the tumor site. This distinctive targeting capability uniquely positions PanTher to take on the deadliest and most difficult to treat cancers with a lead investigational candidate in pancreatic cancer.

Portfolio highlights

• GaeaStar — The zero waste disposable clay cups. GaeaStar is an engineering company developing sustainable single use products and technology.
• MOGL — MOGL is created for athletes by athletes. The platform empowers all athletes to seek out opportunities to monetize their name, image, and likeness in a safe...
• PrivacyHawk — Privacyhawk is a mobile app that empowers everyone to take back control of their privacy.

Portfolio highlights

• Kate Therapeutics — Kate Therapeutics is a patient-focused biotechnology company developing AAV-based gene therapies to treat genetically defined muscle and heart diseases.
• Nexo Therapeutics — Nexo Therapeutics is a small molecule oncology company dedicated to the discovery and development of new drugs for cancer patients who currently lack meaningful therapies.
• Tentarix Biotherapeutics — Tentarix creates innovative protein therapeutics with uniquely combined bioactivities that leverage synthetic biology. The company develops a protein engineering platform designed for multispecific therapies.

Portfolio highlights

• Reglagene — Reglagene is a therapeutics company that leverages its expertise in the design and development of brain penetrant medicines to create breakthrough therapies for the safe and effective treatment of brain diseases.
• RealSeq Biosciences — RealSeq Biosciences’ core expertise includes innovative proprietary technologies for bias-free small RNA/miRNA NGS library construction.
• Trio Pharmaceuticals — TRIO Pharmaceuticals, Inc. is a cancer immunotherapeutics company pioneering dual action drugs to generate immunogenic tumors. TRIO's innovative antibody drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways.

Portfolio highlights

• CaseCTRL — Schedule surgeries with ease using AI-powered surgical scheduling. Fewer canceled cases, conflicts, and misorders. More surgery and time for patients!
• Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
• Amplified Sciences — Amplified Sciences is a molecular diagnostics company unlike other diagnostics companies due to their ultra-sensitive molecular sensing technology with composition of matter IP exclusively licensed from Purdue University. The technology is disease state agnostic, can detect to the single molecule level, scales easily to point of care, and providesa very favorable cost structure for their platform of reagents. The first application – early detection of pancreatic cancer - is an assay that will quickly prove the investment thesis due to large unmet medical need and a favorable reimbursement path. The team has delivered a working prototype and published proof of concept data.

Portfolio highlights

• Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
• SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
• Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.

Portfolio highlights

• Healthsense — Healthsense is a provider of remote monitoring technology solutions for the senior care continuum. With our full range of health and safety monitoring systems, providers are empowered to proactively deliver the highest quality care possible through critical health information. Caregivers reduce costs, increase independence and enhance seniorexperiences when armed with the right information at the right time.
• EndoGastric Solutions — EndoGastric Solutions, Inc. (www.endogastricsolutions.com), is a medical device company developing and commercializing innovative, evidence-based, incisionless surgical technology for the treatment of GERD. EGS has combined the most advanced concepts in gastroenterology and surgery to develop the Transoral Incisionless Fundoplication (TIF®) 2.0procedure—a minimally invasive solution that addresses a significant unmet clinical need.EndoGastric Solutions, Inc. was founded in 2003 and is headquartered in Redmond, Washington.
• Minimally invasive devices — MID has developed the FloShield system, a franchise of products that substantially improve visualization during laparoscopic surgery. During laparoscopic surgery, it is common for condensation to form on the end of the laparoscope obscuring vision. It is also common for debris from the ultrasonic scalpel, cautery, or even blood products themselvesto degrade the surgical view. Most commonly, surgeons will need to remove the laparoscope for manual cleaning. It was founded in 2006 and headquartered in Columbus, Ohio.

Portfolio highlights

• Captions — Say hello to Captions, the only camera and editing app that automatically transcribes, captions and clips your talking videos for you.
• Flagship — Flagship develops a SaaS data science solution that brings predictive machine-learning intelligence to retail. Its centralized platform helps businesses make timely, data-driven decisions across internal stakeholders and channels. Flagship enriches retail brands' first-party data with machine learning algorithms to optimize customer retention,inventory sell-through, and revenue.
• Lightforce Orthodontics — LightForce Orthodontics, founded in 2015, makes the world’s first and only fully customized 3D-printed bracket system that is based on the anatomy and tooth morphology of each patient. The company’s mission is to apply modern technology and mass-customization to improve the orthodontic experience for both patients and doctors. LightForce’s platformunites the latest in digital treatment capabilities with cutting-edge, on-demand, 3D manufacturing to offer clinicians the first significant advancement in bracket-based treatment protocol in the past 50 years. A first-of-its-kind in the orthodontic space, Lightforce offers an unparalleled platform for orthodontists and LightForce technicians to collaborate on treatment plans for each individual patient. The company’s solution significantly reduces patient visits to the orthodontist and time spent wearing braces by providing 100 percent fully-customized solutions that improve both convenience and quality, ensuring patients receive the gold standard of care.

Portfolio highlights

• Gravia — More benefits. Fewer asterisks. We are a health benefits company on a mission to build a health plan that everyone can love.
• EBR Systems — EBR Systems, Inc. is an early-stage development venture pursuing novel approaches in cardiac rhythm management. EBR Systems develops devices for the treatment of cardiac arrhythmias.
• Gravie — More benefits. Fewer asterisks. We are a health benefits company on a mission to build a health plan that everyone can love.

Portfolio highlights

• Luminopia — Luminopia is pioneering a new class of treatments for significant neuro-visual disorders. Luminopia is committed to creating digital therapeutics that are both rigorously evaluated for FDA approval and genuinely engaging for patients. As an Innovation Partner of Boston Children’s Hospital, the company is developing its lead product, Luminopia One,to treat amblyopia, the leading cause of vision loss among children. For more information, visit luminopia.com.
• Presidio Medical — Building Tomorrow's Neuromodulation Therapies. Presidio Medical is a clinical-stage, privately held medical technology company developing a transformational neuromodulation platform to treat diseases of undesired neural activity.
• Laplace Interventional — Laplace developing Transcatheter Tricuspid Valve Technology to offer an increase in life expectancy and an improvement to the quality of life to worldwide patients with tricuspid regurgitation.

Portfolio highlights

• Avedro — Glaukos works relentlessly to create and deliver transformative therapies for patients struggling with glaucoma, corneal disorders, and retinal diseases.
• Milo — Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.
• Spinal Kinetics — The artificial disc replacement device from Orthofix is changing the lives of people suffering from spinal pain. Learn about this motion-saving product.

Portfolio highlights

• Flare Therapeutics — Flare Therapeutics is a biotechnology company opening up a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders, Flare’s team has uncovered ‘switch sites,’ druggable regions that are key targets fortranscription factor regulation to address mutations that cause disease. Our drug discovery to target switch sites has rapidly advanced, resulting in an emerging pipeline of drug programs that address well-validated transcription factors, initially focused on precision oncology with future potential in neurology, rare genetic disorders, immunology, and inflammation.
• Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
• CARGO Therapeutics — CARGO Therapeutics develops CAR T-cell therapy to overcome cancer treatment resistance and address access barriers so that more patients can benefit from potentially curative therapies. The company is on a mission to outwit cancer by developing best-in-class chimeric antigen receptor (CAR) T-cell therapies. Despite commercially available autologousCARs advancements, these treatments are curative for less than half of all cancer patients. Furthermore, far too many patients are unable to access these potentially curative therapies due to other obstacles such as manufacturing, supply constraints, long turnaround times, and reimbursement barriers. CARGO's team is intensely focused on pursuing novel solutions to improve cancer treatment outcomes and experiences.

Portfolio highlights

• KittyCAD — Infrastructure for hardware design tools.
• Paxton AI — Regulatory Intelligence, with the speed of Generative AI.
• Atropos Health — Atropos Health rapidly provides personalized real-world evidence for any clinical decision

Portfolio highlights

• Peptyde Bio — Launched by the Danforth Technology Company, Peptyde Bio combines nature and artificial intelligence to develop nature-based biofungicides.
• SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
• Impetus Agriculture — Impetus Agriculture focuses on developing multiple topical or transgenic insect control products. Products that are safe, effective, and sustainable. Products that are not subject to the same insect resistance that has developed in current commercial products.

Portfolio highlights

• InnoSIGN — We are passionate to bring to market our OncoSIGNal pathway activity profiling technology contributing to a better understanding of disease mechanisms in oncology. OncoSIGNal enables next generation precision medicine by translating molecular data into functional cell behavior.
• Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.
• Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Portfolio highlights

• Nevro — We Believe True Innovation Transforms More Lives
• Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
• Access Closure — Access Closure, Inc., a medical device company, provides access site management products to address the complex challenge of vascular closure during interventional and diagnostic procedures. The company's products include Mynx delivery system, a vascular closure device that seals the arteriotomy using a water-soluble and extravascular sealant,which expands in the tissue tract by absorbing blood and subcutaneous fluids. Access Closure, Inc. was founded in 2002 and is based in Mountain View, California.

Portfolio highlights

• WRANGLD — WRANGLD operates as a SaaS company that provides a platform for the trades and service industries.
• OpsCanvas — Traditional deployments often involve writing hundreds of lines of complex IaC code, which can be time-consuming and prone to errors. OpsCanvas changes the game by offering Draw and Deploy deployments using generative IaC, which automates the production of configuration file code and abstracts the difficult and necessary tasks required in the deployment process.
• Liquet Medical — Liquet Medical is a medical device development company that transforms the way the vascular disease is treated through localized drug delivery. The Versus Catheter will be Liquet Medical’s first technology to market.

Portfolio highlights

• SafeRide Health — SafeRide Health provides technology-forward non-emergency medical transportation (NEMT) services for care providers and health plans offering Medicare Advantage and Medicaid. We intelligently improve and simplify NEMT to improve health outcomes and healthcare satisfaction.
• Rainforest — Rainforest focuses on providing software platforms for payment processing. Rainforest is headquartered in Atlanta, United States.
• Olema Oncology — At Olema Oncology, we leverage our deep understanding of endocrine-driven cancers, nuclear receptors and mechanisms of acquired resistance with the goal of transforming the standard of care for women living with cancer by focusing on developing more convenient and effective therapies. Join us as we aim to design therapies for improving lives.

Portfolio highlights

• MEDIVIS — Medivis is a leader in AR for healthcare, using augmented reality and artificial intelligence to advance medical imaging and surgical precision.
• The Contract Network — AI-powered collaborative contracting is an innovative approach to contract negotiation that emphasizes real-time collaboration, communication, and transparency.
• Collaborative Robotics — Collaborative Robotics is a team of innovators and builders redefining the future of human-robot interaction.

Portfolio highlights

• HomeOptions — Home ownership redefined - We pay homeowners to be their future real estate broker.
• Auriga Space — Next-generation space launch company providing frequent, sustainable and affordable transport to low Earth orbit
• Immersive Fox — Immersive Fox develops a text-to-video B2B service to generate video content for companies remotely. It also creates AI-generated microlearning videos from any text for learning management systems and corporate communication.

Portfolio highlights

• Cardiosense — Cardiosense offers a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease. Its platform leverages multi-modal sensors and industry-leading AI to develop predictive biomarkers for the detection and treatment of disease.
• Aer Therapeutics — Aer Therapeutics is a clinical stage biopharmaceutical company developing a novel inhaled approach to treat lung disease with excess mucus and mucus plugs.
• Mercy BioAnalytics — We are making early stage cancer 100,000x easier to find using extracellular vesicles found in blood, specific to their parent cells.

Portfolio highlights

• Surge — PreCyte integrates high-resolution immune system exploration with predictive information to develop preventive strategies, treatments, medical devices.
• Zeda — Where ideas become reality Zeda's objective is to better lives by investing in cutting-edge technologies, innovative companies, and groundbreaking ideas. Leveraging Advanced Manufacturing Helping companies solve some of their most difficult challenges Series B Announcement Zeda, Inc. (previously PrinterPrezz / Vertex Manufacturing), a global leader in advanced 3D manufacturing and nanotech solutions for the medical,
• Smartlens — Smartlens, Inc. is a medical technology company making non-invasive soft contact lenses as a convenient and affordable way of diurnal IOP (eye pressure) measurement. Smartlens helps with screening, diagnosis, and treatment of Glaucoma - the leading cause of irreversible blindness.

Portfolio highlights

• Nalu Bio — Nalu Bio is the leading innovator in the discovery and production of next generation cannabinoid ingredients.
• EliseAI — Elise is an artificially intelligent leasing agent for multifamily communities. As an AI leasing assistant, Elise responds, follows up, and books showing appointments.
• Jurata Thin Film — Revolutionizing the manufacturing, storage, and delivery of vaccines and biologics

Portfolio highlights

• Jaia Robotics — Aquatic data collection is our passion using micro sized low cost hybrid autonomous surface vehicles and underwater vehicles.
• Lenoss Medical — Lenoss Medical engages in providing solutions that support the natural osseous healing process. They disrupt the treatment of spinal fractures with the osteopearl VBA system, a viable, minimally invasive, and cement-free technology that utilizes the natural healing properties of healthy bone.
• Advanced Silicon Group — Advanced Silicon Group operates a nanotechnology company dedicated to commercializing silicon nanotechnology. The company was founded in 2015 with the goal of commercializing silicon nanotechnology developed by ASG employees.

Portfolio highlights

• Meeno — Meeno is a relationship mentoring app powered by generative AI
• Rocket.Chat — Explore Rocket.Chat, where we put data privacy into every conversation and enable teams to collaborate seamlessly.
• Pulumi — Pulumi's open source infrastructure as code SDK enables you to create, deploy, and manage infrastructure on any cloud, using your favorite languages.

Portfolio highlights

• Validic — Meet the only EHR-integrated remote care solution delivering personalized care for clinicians and patients, making personal health data actionable.
• Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
• Worlds — Worlds is completely re-inventing how organizations see and understand their worlds. Through live, AI-powered models, the company’s clients can remotely see, learn and analyze their worlds in ways that were never possible before.