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Top 50 Health Care VC Funds & Investors in United States (May 2026)

The most active venture capital funds investing in United States Health Care startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Health Care startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Innova Memphis
VC Fund
132 United States, Argentina, United Kingdom Seed, Pre-Seed, Convertible Note Health Care, Medical, Medical Device $50k–$1.5M
ARCH Venture Partners
VC Fund
98 United States, China, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $7M–$230M
Khosla Ventures
VC Fund
91 United States, India, United Kingdom Series A, Series B, Seed Software, Health Care, Artificial Intelligence $1.5M–$60M
New Enterprise Associates
VC Fund
90 United States, India, China Series B, Series A, Series C Software, Health Care, Biotechnology $5M–$85M
Right Side Capital Management
VC Fund
89 United States, Canada, United Kingdom Seed, Pre-Seed, Convertible Note Software, SaaS, Health Care $10k–$1.7M
Rock Health Capital
VC Fund
85 United States, Denmark Seed, Series A, Series B Health Care, Software, Medical $20k–$44M
StartUp Health
VC Fund
80 United States, Canada, United Kingdom Seed, Pre-Seed Health Care, Wellness, Medical $20k–$2.5M
Connecticut Innovations
VC Fund
77 United States, Israel, Canada Series A, Seed Health Care, Biotechnology, Software $150k–$25M
F-Prime Capital
VC Fund
77 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$135M
Alumni Ventures
VC Fund
75 United States, United Kingdom, Canada Seed, Series A, Series B Software, Information Technology, Health Care $850k–$45M
OrbiMed
VC Fund
72 United States, China, Israel Series B, Series A, Series C Biotechnology, Health Care, Pharmaceutical $10M–$120M
Canaan Partners
VC Fund
71 United States, Israel, India Series A, Series B, Series C Software, Biotechnology, Health Care $4.4M–$57M
Gaingels
VC Fund
70 United States, Canada, Germany Seed, Series A, Series B Software, Health Care, FinTech $1.2M–$70M
Polaris Partners
VC Fund
70 United States, Singapore, Ireland Series B, Series A, Series C Biotechnology, Health Care, Medical $3.5M–$117M
Versant Ventures
VC Fund
69 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $3.9M–$85M
Alexandria Venture Investments
VC Fund
66 United States, France, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $7.8M–$150M
Atlas Venture
VC Fund
65 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.6M–$50M
BioAdvance
VC Fund
64 United States, Canada Seed, Series A Biotechnology, Health Care, Medical $200k–$25M
First Round Capital
VC Fund
64 United States, Canada, India Seed, Series A, Series B Software, E-Commerce, Health Care $1M–$40M
Lux Capital
VC Fund
63 United States, Canada, United Kingdom Series A, Seed, Series B Software, Health Care, Biotechnology $1.6M–$66M
Andreessen Horowitz
VC Fund
62 United States, United Kingdom, Canada Series A, Series B, Seed Software, Information Technology, Internet $1.4M–$100M
General Catalyst
VC Fund
61 United States, United Kingdom, India Series A, Series B, Seed Software, Health Care, Internet $1M–$80M
5AM Ventures
VC Fund
61 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $8M–$110M
MPM Capital
VC Fund
61 United States, Canada, Germany Series B, Series A, Series C Biotechnology, Health Care, Pharmaceutical $6.5M–$131M
Founders Fund
VC Fund
60 United States, United Kingdom, Germany Series A, Seed, Series B Software, Health Care, Internet $1.2M–$75M
Third Rock Ventures
VC Fund
59 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $10M–$108M
Portfolia
VC Fund
57 United States, Canada, Argentina Seed, Series A, Series B Health Care, Software, Biotechnology $48k–$15M
SVA
VC Fund
56 United States, Canada, United Kingdom Seed, Series A, Series B Software, Internet, Mobile $600k–$75M
BoxGroup
VC Fund
53 United States, France, Mexico Seed, Series A, Series B Software, Health Care, Internet $1.3M–$70M
HealthTech Capital
VC Fund
52 United States Seed, Series A, Convertible Note Health Care, Medical Device, Medical $1M–$11M
Google Ventures
VC Fund
51 United States, United Kingdom, Canada Series B, Series A, Seed Software, Health Care, Biotechnology $1M–$83M
Wavemaker 360
VC Fund
50 United States, United Kingdom, Canada Seed, Series A Health Care, Medical, Medical Device $100k–$24M
Rev1 Ventures
VC Fund
48 United States, Germany Seed, Series A Software, Health Care, Information Technology $150k–$3.2M
Kleiner Perkins
VC Fund
47 United States, China, United Kingdom Series B, Series A, Series C Software, Health Care, Information Technology $4.1M–$100M
MB Venture Partners
VC Fund
47 United States, Israel Seed, Series B, Series C Health Care, Medical, Medical Device $50k–$28M
Great Oaks Venture Capital
VC Fund
47 United States, United Kingdom, Spain Seed, Series A, Series B E-Commerce, Software, Health Care $650k–$32M
DCVC
VC Fund
46 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Health Care $1.3M–$130M
TEDCO
VC Fund
46 United States Seed, Pre-Seed, Series A Software, Health Care, Biotechnology $25k–$5M
Felicis
VC Fund
45 United States, Canada, Germany Series A, Seed, Series B Software, SaaS, Health Care $1M–$45M
Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund
45 United States Seed, Grant, Debt Financing Health Care, Software, Information Technology $5k–$1.6M
Wisconsin Investment Partners
VC Fund
45 United States, Canada, United Kingdom Seed, Series A Health Care, Biotechnology, Medical $134k–$17M
Hatteras Venture Partners
VC Fund
45 United States, Canada Series A, Series B Biotechnology, Health Care, Medical $2.6M–$90M
Fifty Years
VC Fund
44 United States, Germany, Canada Seed, Series A, Series B Biotechnology, Health Care, Medical $1.3M–$80M
True Ventures
VC Fund
44 United States, United Kingdom, Finland Series A, Seed, Series B Software, Information Technology, Internet $1M–$35M
Greycroft
VC Fund
43 United States, United Kingdom, Germany Series A, Seed, Series B Software, E-Commerce, Internet $1.5M–$45M
8VC
VC Fund
42 United States, Canada, Colombia Seed, Series A, Series B Software, Health Care, Information Technology $2.5M–$120M
Slow Ventures
VC Fund
42 United States, Israel, United Kingdom Seed, Series A, Series B Software, Internet, Health Care $1M–$65M
Asset Management Ventures (AMV)
VC Fund
42 United States, Cyprus, Ireland Series A, Seed, Series B Health Care, Biotechnology, Software $300k–$35M
Boston Harbor Angels
VC Fund
42 United States, Canada, India Angel, Seed, Series A Biotechnology, Health Care, Medical Device $100k–$7.3M
Cultivation Capital
VC Fund
42 United States, Australia, Israel Series A, Seed Software, SaaS, Health Care $250k–$9M
Access all 8206 VC funds in United States Health Care startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Innova Memphis
VC Fund · Memphis, Tennessee, United States · 132 investments in United States Health Care startups

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Pre-Seed, Convertible Note
  • Geography: United States, Argentina, United Kingdom

Investor stats

  • Total investments: 240
  • Round size: Seed $50k–$1.5M; Pre-Seed $50k–$1.3M; Convertible Note $250k–$1.4M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: May invest from a new fund soon — raised $31M in 2017

Portfolio highlights

  • Isomark Health — Isomark Health is a patented AI-based, real-time and 100% green breath technology that detects and prevents bacterial and viral infections.
  • Rantizo — Rantizo provides drone spraying systems and support services for custom applicators, agribusinesses and contractors. Elevating precision ag.
  • Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.
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ARCH Venture Partners
VC Fund · Chicago, Illinois, United States · 98 investments in United States Health Care startups, 22 in the past 12 months

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, Canada

Investor stats

  • Total investments: 303
  • Round size: Series A $7M–$100M; Series B $14M–$230M; Series C $12M–$104M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — raised $3B in 2022

Portfolio highlights

  • AIRNA — AIRNA is on a mission to transform the lives of patients with rare and common diseases by pioneering thediscovery and development of RNA editing therapeutics.
  • Generate Biomedicines — Generate Biomedicines is a biotechnological company focusing on creating breakthrough medicines.
  • Lightcast Discovery — Flexible control over droplet number, occupancy, location and movement. Enabling efficient, multi-step workflows with unprecedented flexibility.
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 91 investments in United States Health Care startups, 58 in the past 12 months

Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 763
  • Round size: Seed $1.5M–$7M; Series A $4.3M–$26M; Series B $8M–$60M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • CellFE — CellFE is a company developing a microfluidics based device to deliver gene-editing molecules. CellFE developed microfluidic device and process that can efficiently deliver gene-editing molecules into the human cells.
  • rabbit — Revolutionizing human-machine interaction
  • Vayu Robotics — Vayu Robotics is an AI robotics company that develops and commercializes automotive sensing, autonomous vehicles, and robotics technology.
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New Enterprise Associates
VC Fund · Menlo Park, California, United States · 90 investments in United States Health Care startups, 47 in the past 12 months

New Enterprise Associates, Inc. is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors, and geographies. With over $19 billion in cumulative committed capital since the firm’s founding in 1977, NEA invests in technology and healthcare companies at all stages in a company’slifecycle, from the seed stage through IPO. The firm's long track record of successful investing includes more than 210 portfolio company IPOs and more than 360 acquisitions.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series B, Series A, Series C
  • Geography: United States, India, China

Investor stats

  • Total investments: 1323
  • Round size: Series A $5M–$43M; Series B $8M–$62M; Series C $11M–$85M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Meeno — Meeno is a relationship mentoring app powered by generative AI
  • Rocket.Chat — Explore Rocket.Chat, where we put data privacy into every conversation and enable teams to collaborate seamlessly.
  • Pulumi — Pulumi's open source infrastructure as code SDK enables you to create, deploy, and manage infrastructure on any cloud, using your favorite languages.
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Right Side Capital Management
VC Fund · San Francisco, California, United States · 89 investments in United States Health Care startups, 6 in the past 12 months

Right Side Capital Management is a venture capital firm that helps startups build their company. It invests exclusively in the pre-seed round of technology startups and makes 75-100 investment per year. The firms prefers to invest in diversified technology sectors such as the internet and cloud companies.RSCM was established in 2010 and is basedin San Francisco, California.

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Investment focus

  • Industry: Software, SaaS, Health Care
  • Stage:Seed, Pre-Seed, Convertible Note
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 570
  • Round size: Seed $10k–$1.7M; Pre-Seed $20k–$315k; Convertible Note $50k–$500k
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • OFFSITE — OFFSITE provides cloud computing and data center solutions.
  • Offsite — Offsite operates a platform that provides retreat planning for remote and hybrid teams. The company helps in the planning, management, and follow-up of team retreats, client-facing events, and other transformational, in-person experiences.
  • ZippedScript — ZippedScript is an application programming interface system developer that specializes in automatically verifying educational details. ZippedScript is located in Toronto, Ontario.
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Rock Health Capital
VC Fund · San Francisco, California, United States · 85 investments in United States Health Care startups

We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.

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Investment focus

  • Industry: Health Care, Software, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, Denmark

Investor stats

  • Total investments: 104
  • Round size: Seed $20k–$2.5M; Series A $1.7M–$37M; Series B $8M–$44M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • WellTheory — Our programs support autoimmune lifestyle changes with an actionable and supportive membership experience, no matter where you are in your autoimmune journey.
  • Oula Health — Oula is a modern maternity clinic combining the best of obstetrics and midwifery care to deliver an evidence-based and personalized pregnancy experience
  • Ribbon Health — Ribbon Health is building the infrastructure to transform healthcare decisions: with accurate and actionable provider information, including insurance coverage, prices, and performance.
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StartUp Health
VC Fund · New York, New York, United States · 80 investments in United States Health Care startups, 12 in the past 12 months

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

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Investment focus

  • Industry: Health Care, Wellness, Medical
  • Stage:Seed, Pre-Seed
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 140
  • Round size: Seed $100k–$2.5M; Pre-Seed $20k–$800k
  • Lead/follow: 4% lead, 96% follow
  • Last fund: May invest from a new fund soon — raised $31M in 2018

Portfolio highlights

  • AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
  • Medwise.ai — Medwise.ai is the Google for doctors.
  • Pear Suite — Pear Suite enables anyone—community health workers, other healthcare staff, and volunteers—to assess and address the social drivers of health for older adults in a scalable, cost-effective, and person-centered way.
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 77 investments in United States Health Care startups, 9 in the past 12 months

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Series A, Seed
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 211
  • Round size: Seed $150k–$2.3M; Series A $1.8M–$25M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • OOVA — OOVA is a fertility diagnostic company that spun out from Mount Sinai Hospital in New York City. Using patent pending biochemistry and artificial intelligence, OOVA learns a woman’s fertility profile by accurately measuring key hormones over time through daily urine samples. By monitoring this critical balance of hormones, OOVA can help a woman getpregnant, identify reasons she is having trouble getting pregnant, and even expose reproductive health issues like PCOS.
  • Raise Green — Raise Green is the climate tech marketplace for local impact investing licensed with the SEC and FINRA to sell private securities.
  • Driver Technologies — Turn your phone into a dash cam.
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F-Prime Capital
VC Fund · Cambridge, Massachusetts, United States · 77 investments in United States Health Care startups, 32 in the past 12 months

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 313
  • Round size: Series A $5M–$63M; Series B $13M–$135M; Series C $20M–$60M
  • Lead/follow: 27% lead, 73% follow

Portfolio highlights

  • Doceree — Doceree is a pharmaceutical advertising & healthcare marketing company which helps in getting a better healthcare services
  • Avalyn Pharma — This does NOT display on the home page
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
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Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 75 investments in United States Health Care startups, 102 in the past 12 months

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

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Investment focus

  • Industry: Software, Information Technology, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 729
  • Round size: Seed $850k–$7.5M; Series A $1.7M–$26M; Series B $11M–$45M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely still investing — fund raised in 2021

Portfolio highlights

  • SigNoz — SigNoz is an open-source observability tool to help you find issues in your deployed applications & solve them quickly. It provides logs, metrics, and traces under a single pane of glass. Built with ClickHouse as datastore, it is designed to handle enterprise scale.
  • teachme.to — Teachme.to is a community of learners discovering lessons for everything.
  • Canid — We believe vaccinating shouldn't be hard and it shouldn't be a distraction from what's most important: taking care of the kids.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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OrbiMed
VC Fund · New York, New York, United States · 72 investments in United States Health Care startups, 38 in the past 12 months

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, Israel

Investor stats

  • Total investments: 419
  • Round size: Series A $10M–$102M; Series B $23M–$120M; Series C $12M–$108M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Evozyne — We have a new way of thinking about proteins. We've uncovered Nature's hidden rules to build Natural Machines. With our partners, we are changing the world.
  • Adela — Adela is focused on the detection of cancer and other high-morbidity, high-mortality conditions through a blood test.
  • Iambic Therapeutics — Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.
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Canaan Partners
VC Fund · Menlo Park, California, United States · 71 investments in United States Health Care startups, 17 in the past 12 months

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

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Investment focus

  • Industry: Software, Biotechnology, Health Care
  • Stage:Series A, Series B, Series C
  • Geography: United States, Israel, India

Investor stats

  • Total investments: 574
  • Round size: Series A $4.4M–$37M; Series B $6.4M–$57M; Series C $5.5M–$41M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — raised $650M in 2023

Portfolio highlights

  • Acesion Pharma — Acesion Pharma ApS is a Danish biotech company founded in 2011 and based in Copenhagen. Acesion Pharma develops more efficacious and safe drugs for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia.
  • Actio Biosciences — At Actio, we are leveraging advances in genetics and precision medicine to develop life-changing treatments that target underlying shared biology between rare and common diseases. We are applying expertise in genetics, drug discovery, and data sciences to pinpoint targets that not only cause rare diseases with high unmet need, but that also hold promise in more common indications.
  • Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.
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Gaingels
VC Fund · New York, New York, United States · 70 investments in United States Health Care startups, 89 in the past 12 months

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 464
  • Round size: Seed $1.2M–$6M; Series A $4M–$50M; Series B $19M–$70M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely still investing — raised $1.1M in 2023

Portfolio highlights

  • KittyCAD — Infrastructure for hardware design tools.
  • Paxton AI — Regulatory Intelligence, with the speed of Generative AI.
  • Atropos Health — Atropos Health rapidly provides personalized real-world evidence for any clinical decision
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Polaris Partners
VC Fund · Boston, Massachusetts, United States · 70 investments in United States Health Care startups, 13 in the past 12 months

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Singapore, Ireland

Investor stats

  • Total investments: 383
  • Round size: Series A $3.5M–$60M; Series B $5.3M–$117M; Series C $11M–$61M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Tausight — Tausight is specifically designed to help Healthcare ensure the confidentiality, integrity, and availability of ePHI.
  • Candesant Biomedical — Candesant Biomedical develops treatment for excessive sweating and hyperhidrosis. It offers a technology that is based on the principle that alkali metals in contact with water generate energy. The insight was that when the amounts of metal and water are controlled, the result is targeted delivery of energy exactly at the site of the water. Itsdevice is designed to target and inactivate the most active sweat glands.The company was founded in 2016 and is headquartered in San Francisco, California.
  • Crossbow Therapeutics — Crossbow Therapeutics is a seed-stage, stealth-mode oncology startup company. The company develops antibody engineering for intracellular cancer targets.
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Versant Ventures
VC Fund · Menlo Park, California, United States · 69 investments in United States Health Care startups, 7 in the past 12 months

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 253
  • Round size: Series A $3.9M–$68M; Series B $6M–$85M; Series C $6M–$80M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: May invest from a new fund soon — last raise in 2021

Portfolio highlights

  • Kate Therapeutics — Kate Therapeutics is a patient-focused biotechnology company developing AAV-based gene therapies to treat genetically defined muscle and heart diseases.
  • Nexo Therapeutics — Nexo Therapeutics is a small molecule oncology company dedicated to the discovery and development of new drugs for cancer patients who currently lack meaningful therapies.
  • Tentarix Biotherapeutics — Tentarix creates innovative protein therapeutics with uniquely combined bioactivities that leverage synthetic biology. The company develops a protein engineering platform designed for multispecific therapies.
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Alexandria Venture Investments
VC Fund · Pasadena, California, United States · 66 investments in United States Health Care startups, 18 in the past 12 months

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, France, Canada

Investor stats

  • Total investments: 184
  • Round size: Series A $7.8M–$81M; Series B $20M–$150M; Series C $22M–$112M
  • Lead/follow: 6% lead, 94% follow

Portfolio highlights

  • Deka Biosciences — Deka BioSciences, Inc. is committed to developing and delivering life-changing medicines to patients with cancer and inflammatory diseases.
  • Solu Therapeutics — Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells.
  • Arialys Therapeutics — Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience. The company focuses on how the immune system impacts CNS health, disease, and treatment.
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Atlas Venture
VC Fund · Cambridge, Massachusetts, United States · 65 investments in United States Health Care startups, 6 in the past 12 months

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 376
  • Round size: Series A $3.6M–$30M; Series B $7.5M–$50M; Series C $7.5M–$34M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • K36 Therapeutics — K36 Therapeutics mission to translate epigenetic modulation of oncogenic pathways into first-in-class small molecule therapies.
  • Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
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BioAdvance
VC Fund · Philadelphia, Pennsylvania, United States · 64 investments in United States Health Care startups

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada

Investor stats

  • Total investments: 115
  • Round size: Seed $200k–$2.5M; Series A $3M–$25M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: May invest from a new fund soon — last raise in 2002

Portfolio highlights

  • Senzo — SENZO HEALTH HAS DEVELOPED A REVOLUTIONARY LATERAL FLOW TEST WHICH DELIVERS THE SAME ACCURACY AS LABORATORY-BASED PCR, WITH RESULTS AVAILABLE WITHIN 10 MINUTES, AT A FRACTION OF THE COST.
  • KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
  • Palvella Therapeutics — Palvella Therapeutics is committed to developing safe and effective therapies that specifically target the root cause of genetic skin diseases.
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First Round Capital
VC Fund · San Francisco, California, United States · 64 investments in United States Health Care startups, 20 in the past 12 months

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

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Investment focus

  • Industry: Software, E-Commerce, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 648
  • Round size: Seed $1M–$6.6M; Series A $2M–$18M; Series B $5.4M–$40M
  • Lead/follow: 22% lead, 78% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Cymbal — The human readable block explorer. Explore any wallet, NFT or collection to understand their activity, all in real time.
  • Spline — Spline is a free 3D design software with real-time collaboration to create web interactive experiences in the browser. Easy 3d modeling, animation, textures, and more.
  • Ossium Health — Ossium is building the world's first bone marrow bank to treat blood cancers, improve organ transplantation, and repair damage from radiation.The cells of the immune system are the human body’s natural defenders against disease. At Ossium, they are developing better methods of recovering, preserving, deploying these critical cells to keepdisease at bay.
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Lux Capital
VC Fund · New York, New York, United States · 63 investments in United States Health Care startups, 33 in the past 12 months

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 347
  • Round size: Seed $1.6M–$12M; Series A $5.7M–$30M; Series B $12M–$66M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Delphi — Delphi is digital cloning that scales time, monetizes knowledge, and interacts audience at scale.
  • Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.
  • Pivotal Commware — Pivotal Commware was established in 2016 to commercialize a breakthrough in electromagnetic physics, Holographic Beam Forming™ (HBF). Years ago, Pivotal’s founders recognized that wireless demand for data would outgrow the complex coding, multiplexing and modulation schemes that network operators have deployed thus far. Beamforming was theanswer, but existing high cost, size, weight and power-consuming (C-SWaP) solutions were not. That’s why Pivotal assembled a team experienced in advanced commercial antenna and RF circuit design, advanced DARPA technology programs, and, uniquely, active/nonlinear metamaterials. Beyond technology, Pivotal also offers the depth and breadth of skills to develop integrated, end-to-end solutions.
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Andreessen Horowitz
VC Fund · Menlo Park, California, United States · 62 investments in United States Health Care startups, 129 in the past 12 months

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

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Investment focus

  • Industry: Software, Information Technology, Internet
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 1151
  • Round size: Seed $1.4M–$10M; Series A $6.9M–$45M; Series B $15M–$100M
  • Lead/follow: 47% lead, 53% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Castelion — We are a modern defense production company building the next generation of military hypersonic, vehicle, and strike systems to deter future wars.
  • Headway — Headway is a mental healthcare system provider based in New York. It develops a health insurance advisory platform designed to connect patients with therapists and provides administrative support to therapists who don’t typically accept insurance. The company was founded by Andrew Adams, Jake Sussman, Dan Ross, and Kevin Chan in 2019.
  • Blackbird — We believe the next great hospitality technology platform should connect restaurants and their customers directly, in meaningful and ongoing ways. Blackbird is founded by a team with a passion for restaurants and a track record of using technology to solve problems.
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General Catalyst
VC Fund · Cambridge, Massachusetts, United States · 61 investments in United States Health Care startups, 67 in the past 12 months

Investing in powerful, positive change that endures

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Investment focus

  • Industry: Software, Health Care, Internet
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 883
  • Round size: Seed $1M–$7.5M; Series A $5M–$30M; Series B $9M–$80M
  • Lead/follow: 42% lead, 58% follow
  • Last fund: May invest from a new fund soon — raised $600M in 2021

Portfolio highlights

  • Evvy — Evvy is for people with vaginas who want to be empowered with information about their microbiome. Their mission is to close the gender health gap by discovering and leveraging overlooked biomarkers in the female body — starting with the vaginal microbiome.
  • QuriousBit — QuriousBit is a gaming studio that develops casual puzzle games for mobile platforms.
  • Cartwheel — Cartwheel provides multi-tiered, evidenced-based mental health support from licensed clinicians, designed around your entire school community.
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5AM Ventures
VC Fund · Menlo Park, California, United States · 61 investments in United States Health Care startups

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 148
  • Round size: Series A $8M–$46M; Series B $14M–$110M; Series C $12M–$56M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Spruce Biosciences — Developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
  • Novome Biotechnologies — Novome Biotechnologies, Inc. is a biotechnology company focused on engineering defined activities into the human gut microbiota to treat chronic diseases. The Company has developed the first-ever platform for controlled colonization of the gut with engineered bacteria, enabling first-in-class living therapeutics: Genetically Engineered MicrobialMedicines (GEMMs). Novome is utilizing its proprietary GEMMs platform in its lead preclinical program in hyperoxaluria, which is focused on the development of a therapeutic strain of bacteria that degrades oxalate to prevent the formation of kidney stones. Efforts are also directed to the expansion of its proprietary synthetic biology platform into additional indications.
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MPM Capital
VC Fund · Cambridge, Massachusetts, United States · 61 investments in United States Health Care startups, 7 in the past 12 months

Powering Breakthroughs in Life Sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 210
  • Round size: Series A $6.5M–$80M; Series B $20M–$116M; Series C $10M–$131M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: Likely still investing — raised $850M in 2021

Portfolio highlights

  • Deka Biosciences — Deka BioSciences, Inc. is committed to developing and delivering life-changing medicines to patients with cancer and inflammatory diseases.
  • ReCode Therapeutics — ReCode is the first genetic medicines platform to enable highly targeted delivery to organs, tissues and cells beyond the liver. Our pipeline of rare disease therapeutics uses optimized mRNA and gene correction with redosing capability.
  • Arialys Therapeutics — Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience. The company focuses on how the immune system impacts CNS health, disease, and treatment.
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Founders Fund
VC Fund · San Francisco, California, United States · 60 investments in United States Health Care startups, 41 in the past 12 months

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

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Investment focus

  • Industry: Software, Health Care, Internet
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 598
  • Round size: Seed $1.2M–$9.5M; Series A $4M–$40M; Series B $11M–$75M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Layer N — Layer N is a layer 2 network designed to hyper-scale financial applications on Ethereum.
  • Roam — Roam is the platform for affordable home ownership. Roam helps homebuyers purchase their next home with a low-interest rate mortgage included.
  • Regent — We build all-electric, passenger-carrying, wing-in-ground-effect vehicles to service coastal routes with technology available today.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 59 investments in United States Health Care startups

Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 124
  • Round size: Series A $20M–$100M; Series B $10M–$108M; Series C $11M–$78M
  • Lead/follow: 45% lead, 55% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Flare Therapeutics — Flare Therapeutics is a biotechnology company opening up a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders, Flare’s team has uncovered ‘switch sites,’ druggable regions that are key targets fortranscription factor regulation to address mutations that cause disease. Our drug discovery to target switch sites has rapidly advanced, resulting in an emerging pipeline of drug programs that address well-validated transcription factors, initially focused on precision oncology with future potential in neurology, rare genetic disorders, immunology, and inflammation.
  • Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
  • CARGO Therapeutics — CARGO Therapeutics develops CAR T-cell therapy to overcome cancer treatment resistance and address access barriers so that more patients can benefit from potentially curative therapies. The company is on a mission to outwit cancer by developing best-in-class chimeric antigen receptor (CAR) T-cell therapies. Despite commercially available autologousCARs advancements, these treatments are curative for less than half of all cancer patients. Furthermore, far too many patients are unable to access these potentially curative therapies due to other obstacles such as manufacturing, supply constraints, long turnaround times, and reimbursement barriers. CARGO's team is intensely focused on pursuing novel solutions to improve cancer treatment outcomes and experiences.
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Portfolia
VC Fund · San Mateo, California, United States · 57 investments in United States Health Care startups, 17 in the past 12 months

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Argentina

Investor stats

  • Total investments: 154
  • Round size: Seed $2M–$3.7M; Series A $48k–$15M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
  • Prime Roots — Prime Roots is on a mission to provide a better cut of meat for every type of eater. Rooted in koji, Prime Roots is able to replicate the taste and texture of meat without any of the environmental costs of animal proteins.
  • Carbice Corporation — Carbice is the first no-compromise thermal interface material. It achieves all the advantages of both solid and liquid thermal interface materials without any of the pitfalls.
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SVA
VC Fund · San Francisco, California, United States · 56 investments in United States Health Care startups, 44 in the past 12 months

SV Angel is a San Francisco-based venture fund. Their experience spans helping companies like Airbnb, Coinbase, Databricks, DoorDash, Faire, Flexport, GitHub, Notion, Pinterest, Snap, Square, and Stripe Scale. Over the last 30 years of investing, their core values of trust, loyalty, and integrity along with a founder-first approach have driven ourstrategy. They are a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

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Investment focus

  • Industry: Software, Internet, Mobile
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 775
  • Round size: Seed $600k–$6M; Series A $2M–$20M; Series B $6.3M–$75M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Induced AI — Induced AI works to automate browser tasks. It runs a cloud to complete manual tasks on a browser with human-like reasoning capabilities.
  • Modular — Modular is the next-generation AI developer platform unifying the development and deployment of AI for the world.
  • Evidence — Evidence is an open source, code-based alternative to drag-and-drop BI tools. Build polished data products with just SQL and markdown.
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BoxGroup
VC Fund · New York, New York, United States · 53 investments in United States Health Care startups, 40 in the past 12 months

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

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Investment focus

  • Industry: Software, Health Care, Internet
  • Stage:Seed, Series A, Series B
  • Geography: United States, France, Mexico

Investor stats

  • Total investments: 362
  • Round size: Seed $1.3M–$6.3M; Series A $2M–$25M; Series B $11M–$70M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: Likely still investing — fund raised in 2021

Portfolio highlights

  • Cartwheel — Cartwheel provides multi-tiered, evidenced-based mental health support from licensed clinicians, designed around your entire school community.
  • Granular Energy — Granular Energy provides solutions for managing and trading clean energy. Our tools have been developed to support the recent emergence of 24/7 time-stamped energy certificates as well as traditional "annual" certificates.
  • Rainforest — Rainforest focuses on providing software platforms for payment processing. Rainforest is headquartered in Atlanta, United States.
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HealthTech Capital
VC Fund · Los Altos Hills, California, United States · 52 investments in United States Health Care startups

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States

Investor stats

  • Total investments: 83
  • Round size: Seed $1M–$3.4M; Series A $1.6M–$11M
  • Lead/follow: 12% lead, 88% follow

Portfolio highlights

  • Agile Therapeutics — Agile Therapeutics, Inc., a specialty pharmaceutical company, engages in the development of women's healthcare products. It offers a low estrogen dose seven-day transdermal contraceptive patch system that delivers a combination of levonorgestrel and Ethinylestradiol. The company was founded in 1997 as Levotech, Inc. and changed its name toAgile Therapeutics, Inc. in April 2001. It is based in Princeton, New Jersey.
  • GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
  • Wavely Diagnostics — Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.
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Google Ventures
VC Fund · Mountain View, California, United States · 51 investments in United States Health Care startups, 56 in the past 12 months

GV supports innovative founders moving the world forward.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series B, Series A, Seed
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 770
  • Round size: Seed $1M–$5.2M; Series A $4M–$55M; Series B $9.4M–$83M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
  • Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
  • ROME Therapeutics — ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome – vast stretches of uncharted genetic material that have long been dismissed as “junk DNA.” With several drug targets identified and multiple discovery programs underway, ROME is moving rapidly to leverage this new frontier inbiology. To lead this exploration, ROME has assembled a team of world-class leaders across fields including oncology, immunology, virology and machine learning.
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Wavemaker 360
VC Fund · Pasadena, California, United States · 50 investments in United States Health Care startups, 6 in the past 12 months

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Series A
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 66
  • Round size: Seed $250k–$6M; Series A $100k–$24M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • 32Co — 32Co is a medical technology platform that helps general dentists deliver clear aligner orthodontics to their patients.
  • Essenvia — Rapidly submit eSTAR, EUMDR and IVDR applications, eliminate errors and accelerate approvals with the only regulatory submission platform made for MedTech
  • Gradient Health — One of the biggest barriers to accelerating AI development is access to large datasets of labeled pathologies.
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 48 investments in United States Health Care startups, 7 in the past 12 months

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 171
  • Round size: Seed $150k–$2.6M; Series A $1.2M–$3.2M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — fund raised in 2021

Portfolio highlights

  • Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
  • MentorcliQ — Mentoring programs that drive employee engagement, development, and retention with MentorcliQ's award-winning mentoring software and approach. See why our customers love us!
  • SureImpact — SureImpact is a user-friendly, social services case management software that helps you track and report outcomes, measure participant needs, and demonstrate impact to funders.
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Kleiner Perkins
VC Fund · Menlo Park, California, United States · 47 investments in United States Health Care startups, 15 in the past 12 months

Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 960
  • Round size: Series A $4.1M–$30M; Series B $10M–$50M; Series C $10M–$100M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Captions — Say hello to Captions, the only camera and editing app that automatically transcribes, captions and clips your talking videos for you.
  • Flagship — Flagship develops a SaaS data science solution that brings predictive machine-learning intelligence to retail. Its centralized platform helps businesses make timely, data-driven decisions across internal stakeholders and channels. Flagship enriches retail brands' first-party data with machine learning algorithms to optimize customer retention,inventory sell-through, and revenue.
  • Lightforce Orthodontics — LightForce Orthodontics, founded in 2015, makes the world’s first and only fully customized 3D-printed bracket system that is based on the anatomy and tooth morphology of each patient. The company’s mission is to apply modern technology and mass-customization to improve the orthodontic experience for both patients and doctors. LightForce’s platformunites the latest in digital treatment capabilities with cutting-edge, on-demand, 3D manufacturing to offer clinicians the first significant advancement in bracket-based treatment protocol in the past 50 years. A first-of-its-kind in the orthodontic space, Lightforce offers an unparalleled platform for orthodontists and LightForce technicians to collaborate on treatment plans for each individual patient. The company’s solution significantly reduces patient visits to the orthodontist and time spent wearing braces by providing 100 percent fully-customized solutions that improve both convenience and quality, ensuring patients receive the gold standard of care.
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MB Venture Partners
VC Fund · Memphis, Tennessee, United States · 47 investments in United States Health Care startups

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Series B, Series C
  • Geography: United States, Israel

Investor stats

  • Total investments: 90
  • Round size: Seed $50k–$700k; Series B $1.3M–$18M; Series C $5M–$28M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — last raise in 2011

Portfolio highlights

  • Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
  • SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
  • Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.
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Great Oaks Venture Capital
VC Fund · New York, New York, United States · 47 investments in United States Health Care startups, 14 in the past 12 months

Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.

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Investment focus

  • Industry: E-Commerce, Software, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Spain

Investor stats

  • Total investments: 307
  • Round size: Seed $650k–$4.1M; Series A $3.7M–$15M; Series B $6.2M–$32M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: May invest from a new fund soon — last raise in 2013

Portfolio highlights

  • Leverage — Answering the Fundamental Question: "Where
  • Lex — Lex is a lo-fi, text-based social app for womxn, trans, genderqueer, intersex, two spirit, and non-binary people for meeting lovers and friends. Lex—short for lexicon—is the only social app where the text comes first and the selfies, second.
  • Dashy Dash — Dashy Dash is a free community powered tool that makes it easy to manage invoices, discover new products & compare prices to help you save money.
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DCVC
VC Fund · San Francisco, California, United States · 46 investments in United States Health Care startups, 25 in the past 12 months

We are deep tech venture capital.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 318
  • Round size: Seed $1.3M–$8M; Series A $5.7M–$20M; Series B $14M–$130M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Noetik — Noetik is an AI-native biotechnology company. Our mission is to leverage advanced machine learning methods to discover and develop cancer immunotherapies.
  • CH4 Global — CH4 Global is bending the curve with climate change solutions. We leverage red seaweed to help with methane reduction. Learn more our AgTech Solutions today!
  • Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.
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TEDCO
VC Fund · Columbia, Maryland, United States · 46 investments in United States Health Care startups, 11 in the past 12 months

TEDCO was created by the Maryland State Legislature in 1998 to facilitate the transfer and commercialization of technology from Maryland’s research universities and federal labs into the marketplace and to assist in the creation and growth of technology-based businesses in all regions of the State. TEDCO is an independent organization thatstrives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy. In Maryland and beyond, TEDCO is a resource of mentoring, funding and networking for entrepreneurs and start-ups that need guidance as they bring innovative concepts to market. TEDCO is more than an early stage funding resource. It is the hub of Maryland’s entrepreneurial network where startups find mentors, organizational assistance, facilities for daily operations, and a roadmap for success.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States

Investor stats

  • Total investments: 131
  • Round size: Seed $100k–$2.5M; Pre-Seed $25k–$1.1M; Series A $80k–$5M
  • Lead/follow: 39% lead, 61% follow

Portfolio highlights

  • Hopr — Hopr recognizes the increasing relevance of cybersecurity in today's global digital society. Hopr objective is to assist organizations in protecting their digital operations and data by rethinking old challenges and then developing innovative cybersecurity solutions to tackle them.
  • Fem Equity — Fem Equity is a work platform that develops real-time solutions for women and underrepresented professionals experiencing salary or professional inequalities.
  • N5 Sensors — Sensors and solutions for protecting lives and infrastructure from environmental hazards.
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Felicis
VC Fund · Menlo Park, California, United States · 45 investments in United States Health Care startups, 31 in the past 12 months

Backing founders building iconic companies that transcend boundaries

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Investment focus

  • Industry: Software, SaaS, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 413
  • Round size: Seed $1M–$6.7M; Series A $2.5M–$17M; Series B $9M–$45M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Opsera — Opsera automates any CI/CD toolchain, enables declarative pipelines, and provides unified insights across your entire software delivery process.
  • Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
  • MotherDuck — Making analytics ducking awesome with DuckDB. Sign up to stay in touch.
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Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund · Philadelphia, Pennsylvania, United States · 45 investments in United States Health Care startups

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

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Investment focus

  • Industry: Health Care, Software, Information Technology
  • Stage:Seed, Grant, Debt Financing
  • Geography: United States

Investor stats

  • Total investments: 134
  • Round size: Seed $50k–$1.6M; Grant $5k–$100k; Debt Financing $975k–$975k
  • Lead/follow: 40% lead, 60% follow

Portfolio highlights

  • Yellowdig — Yellowdig offers educators a gameful learning digital solution to improve student engagement by building learning communities.
  • ImpactableX — The social impact modeling & management toolkit behind leading solutions to our world's most pressing challenges.
  • GrowFlux — GrowFlux, Inc. they offers a ecosystem of commercial scale wireless lighting controls, cloud services, and cloud connected agricultural sensors.
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Wisconsin Investment Partners
VC Fund · Madison, Wisconsin, United States · 45 investments in United States Health Care startups

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 108
  • Round size: Seed $134k–$3M; Series A $1.1M–$17M
  • Lead/follow: 15% lead, 85% follow

Portfolio highlights

  • Sequoir — Sequoir is a financial technology firm providing blockchain trading and custody APIs to power banks, credit unions, fintech, and the Web 3.0.
  • Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
  • Nurse Disrupted — A virtual nursing program that retains nurses & improves hospital finances. Live in 4 weeks. Engaged, happier nurses in days.
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Hatteras Venture Partners
VC Fund · Durham, North Carolina, United States · 45 investments in United States Health Care startups

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B
  • Geography: United States, Canada

Investor stats

  • Total investments: 105
  • Round size: Series A $2.6M–$50M; Series B $4.5M–$90M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Cardiosense — Cardiosense offers a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease. Its platform leverages multi-modal sensors and industry-leading AI to develop predictive biomarkers for the detection and treatment of disease.
  • Aer Therapeutics — Aer Therapeutics is a clinical stage biopharmaceutical company developing a novel inhaled approach to treat lung disease with excess mucus and mucus plugs.
  • Mercy BioAnalytics — We are making early stage cancer 100,000x easier to find using extracellular vesicles found in blood, specific to their parent cells.
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Fifty Years
VC Fund · San Francisco, California, United States · 44 investments in United States Health Care startups, 11 in the past 12 months

WE BACK HEROES using technology to solve the world's biggest problems

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, Germany, Canada

Investor stats

  • Total investments: 139
  • Round size: Seed $1.3M–$11M; Series A $6M–$30M; Series B $8.5M–$80M
  • Lead/follow: 17% lead, 83% follow
  • Last fund: Likely still investing — fund raised in 2021

Portfolio highlights

  • Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
  • BIOS — BIOS Health is unlocking the potential of the nervous system in treating chronic disease by using AI-powered neural interfaces that can automatically read and write neural signals.
  • Elicit — Elicit is an artificial intelligence research assistant that uses language models to help users automate research workflows. This research assistant finds relevant papers without a perfect keyword match, summarizes takeaways from the papers, and extracts key information from the papers.
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True Ventures
VC Fund · Palo Alto, California, United States · 44 investments in United States Health Care startups, 34 in the past 12 months

A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.

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Investment focus

  • Industry: Software, Information Technology, Internet
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Finland

Investor stats

  • Total investments: 497
  • Round size: Seed $1M–$5.5M; Series A $1.5M–$15M; Series B $3M–$35M
  • Lead/follow: 38% lead, 62% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Deduce — Deduce protects businesses and their customers from unauthorized account access, data leakage, and identity fraud. We eliminate fraud in real-time using risk algorithms and behavioral analytics across the most comprehensive network of consumer identity data. This empowers any organization to harness the value of collective identity-based threatintelligence and cybersecurity.
  • Lex — Lex is a modern writing tool that helps people think through their ideas and communicate more effectively.
  • Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.
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Greycroft
VC Fund · New York, New York, United States · 43 investments in United States Health Care startups, 30 in the past 12 months

Venture capital and technology investments

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Investment focus

  • Industry: Software, E-Commerce, Internet
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 597
  • Round size: Seed $1.5M–$7M; Series A $3M–$20M; Series B $5M–$45M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $378M in 2023

Portfolio highlights

  • JOKR — Grocery shopping is easier now with JOKR, your instant delivery app. Order your groceries and favorite products in our online supermarket and get them instantly at your door. Download the app now and make your first grocery order on us. Available in IOs and Android. Access www.jokr.com for more info
  • Vera — Vera develops an assessment platform to identify and address risks in artificial intelligence and machine learning models. It engages key stakeholders across teams to create data-driven assessments and use data science tools to investigate AI and ML models, helping organizations navigate through uncertainty and protecting companies and individualsfrom risky artificial intelligence systems.
  • Nextdata — Nextdata offers an operating system for decentralized data at scale on an AI platform.
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8VC
VC Fund · San Francisco, California, United States · 42 investments in United States Health Care startups, 42 in the past 12 months

8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Colombia

Investor stats

  • Total investments: 307
  • Round size: Seed $2.5M–$9M; Series A $6M–$50M; Series B $12M–$120M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Aryn — Answer questions on all of your data.
  • ClearFeed — Conversational Support Platform on Slack
  • Reserv — We are a premier claims platform, born from state-of-the-art data intelligence and talent management technology.
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Slow Ventures
VC Fund · San Francisco, California, United States · 42 investments in United States Health Care startups, 18 in the past 12 months

Slow Ventures is a community built on the collective experience and fueled by curiosity, Slow understands the entrepreneurial journey. Investing at the center of technology and on the edges of science, society, and culture, Slow gives founders the resources, connections, experiences, and empathy required to build strong, sustainable companies.

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Investment focus

  • Industry: Software, Internet, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, Israel, United Kingdom

Investor stats

  • Total investments: 334
  • Round size: Seed $1M–$5.3M; Series A $5.4M–$17M; Series B $13M–$65M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: Likely still investing — raised $130M in 2022

Portfolio highlights

  • Gleen AI — Delight your customers. Get Gleen, the world's most accurate & capable generative AI-based chatbot. Trustworthy answers. Automatic actions. Unify knowledge.
  • Teamshares — One hundred percent close rate on LOIs. Committed capital with no financing contingency. Teamshares is the buyer of choice for your business listing. Request a buyer profile to learn more about us.
  • Metropolis — Metropolis unites technology and operations to make parking remarkable.
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Asset Management Ventures (AMV)
VC Fund · Palo Alto, California, United States · 42 investments in United States Health Care startups

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Series A, Seed, Series B
  • Geography: United States, Cyprus, Ireland

Investor stats

  • Total investments: 132
  • Round size: Seed $300k–$6M; Series A $3.3M–$12M; Series B $4M–$35M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • SubjectWell — SubjectWell is the risk-free clinical trials marketplace for patient recruitment
  • Autonomize AI — Autonomize AI is a human-centric AI platform that learns from multi-structured clinical and biomedical data and pairs it with human context to aid decision-making and data discovery. They extract contextual information from multi-structured healthcare data, enrich with human know-how, and aid decision-making and data discovery.
  • Carta Healthcare — Our industry-leading, AI-driven technology converts both structured and unstructured healthcare data into a high-quality, reliable, standardized dataset that can be used across your organization.
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Boston Harbor Angels
VC Fund · Boston, Massachusetts, United States · 42 investments in United States Health Care startups

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical Device
  • Stage:Angel, Seed, Series A
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 104
  • Round size: Seed $100k–$2.4M; Angel $500k–$1.6M; Series A $662k–$7.3M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
  • Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
  • Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.
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Cultivation Capital
VC Fund · St Louis, Missouri, United States · 42 investments in United States Health Care startups, 13 in the past 12 months

Cultivation Capital invests in young companies whose ideas have potential to transform the way we live and work.

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Investment focus

  • Industry: Software, SaaS, Health Care
  • Stage:Series A, Seed
  • Geography: United States, Australia, Israel

Investor stats

  • Total investments: 204
  • Round size: Seed $250k–$4.4M; Series A $1.5M–$9M
  • Lead/follow: 62% lead, 38% follow
  • Last fund: Likely still investing — raised $13M in 2021

Portfolio highlights

  • SATIM — SATIM provides insights based on satellite radar data acquired regardless of weather and day/night time. Using developed software and algorithms SATIM can solve the problem of optimal information extraction from complex SAR imagery.
  • AirDeck — Make documents and presentations more engaging by adding audio or video narration. Add clarity and personalize any content you share.
  • Clever Real Estate — We match you with top agents nationwide and help you save. Sellers get full service for just a 1.5% listing fee. Buyers can get cash back after closing.
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Health Care VC funding in United States at a glance

Stats across 19k deals from 8.2k investors.

8.2k
investors
in United States Health Care startups
19k
deals
in United States Health Care startups
$5.8M
median round
in United States Health Care startups
44%
lead investors
lead at least one round
22%
Seed
most common funding stage

Access all 8206 VC funds in United States Health Care startups.

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