Top 10 Medical Device Startup Investors in South Africa (May 2026)

Portfolio highlights

• Inseco — Inseco is an IT company that specializes in management solutions, ERP, CRM, GED, HR, and business solutions.
• SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.

Portfolio highlights

• Pison — Pison is a human performance company optimizing cognitive and physiological capability through gesture control. It's a full-stack solution combine hardware, software, machine learning, and UX for AR industries and drones. Investors and partners include Special Forces, Air Force, Harris, First Round DRF, MIT, Draper, and NASA.
• Vesper — Vesper is an electrical and electronic manufacturing company that specializes in microphones, piezoelectric, and audio. The company is driven by a mission is to deliver voice-powered products to every market, around the world. Vesper was founded in 2009 and headquartered in Boston, Massachusetts.
• Medrhythms — Pioneering Next-Generation Digital Therapeutics to Improve Walking  

Portfolio highlights

• LIQID Medical — LIQID Medical is a medical equipment manufacturing organization focusing on the development of technological glaucoma treatment devices.

Portfolio highlights

• hearX Group — Digital audiology technology to screen, diagnose & treat hearing loss globally. Award-winning solutions for more efficient & cost-effective hearing care.

Portfolio highlights

• Lengo — Lengo is an AI based intelligence platform that offers a large database on consumer goods for companies in the FMCG sector.
• Zanifu — The zanifu platform, allows small retailers in Sub Saharan Africa, to procure inventory from their suppliers & pay later.
• Fixit45 — Your best ever automobile service experience awaits you.

Portfolio highlights

• Kasha — Kasha is an innovative e-commerce platform based in East Africa, built for women's health, personal care and beauty products accessibility within urban and rural areas.
• Buupass — BuuPass is Kenya's market leader for online bus booking. We enable travelers to reserve seats and make payments in a convenient and timely way. Try BuuPass today!
• Zuri Health — .ts-banner-image-1:hover .overlay{background-color:#ffffff} .ts-banner-image-2:hover .overlay{background-color:#ffffff} Popular categories Pharmacy Doctor at home Covid Labs & Diagonstics Wellness Telemed Show all Our Services PharmacyBuy both OTC and prescription medication and have it delivered to your doorstepLabs & DiagnosticsBook labs and Diagnostic tests and get your samples collected from the comfort of your home, hotel

Portfolio highlights

• Jobox — Jobox is a student recruitment platform, built to connect employers, students and graduate career offices. Our focus is to improve graduate employability by ensuring all students have the skills they need to enter, stay in, and progress in the world of work.Jobox’s ecosystem provides employers with access to the best diverse & youthfultalent, students with more employment opportunities and universities with data-driven insights aimed at driving graduate employability forward.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
• Ownedby Technologies — Ownedby is an interactive asset management solution for business and household assets, focused on appliances and devices, giving these unique identity that is traceable online, yet linked to and controlled by owners.

Portfolio highlights

• STRM.BIO — STRM.BIO specializes in the fields of biotechnology and life science.
• Scentian Bio — Scentian Bio operates as a platform that provides ultimate sensing solution.
• AN2 Therapeutics — AN2 Therapeutics, Inc. is a California-based global health biopharmaceutical company focused on modern biomedical and drug development expertise to provide transformational medicines for patients suffering from infectious diseases. The company was founded in 2017 and is headquartered in Menlo Park, California, United States.

Portfolio highlights

• MX Labs — Allow your user to comprehensively monitor their vital signs. Check wellbeing, prevent misdiagnosis, and motivate lifestyle changes thanks to Shen.AI.
• Saludtools — Saludtools is a digital platform that improves access, quality and reliability of medical services for thousands of patients in Latin America. Our innovative and friendly technology breaks the barriers that prevent a better medical attention. We are about making outstanding healthcare accessible for everyone.
• VitruvianMD — VitruvianMD combines biomedical engineering and state-of-the-art artificial intelligence (AI) to deliver affordable, high-accuracy diagnostic tools for medical laboratories, with a particular focus on servicing emerging markets.

Portfolio highlights

• I-G3N — I-G3N is a South African developer of lithium-ion batteries. The company’s core market is on stationary storage in conjunction with Solar PV and focuses on superior products and on the incorporation of the latest technologies to battery functionality. One of the key focus areas is on exporting to the SADC region and the rest of Africa, asextraordinary opportunities exist on the rest of the continent, especially in the development of mini and micro-grids to impact development.
• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.