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Top 50 Biotechnology VC Funds & Investors in Japan (May 2026)

The most active venture capital funds investing in Japan Biotechnology startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in Japan Biotechnology startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Mitsubishi UFJ Capital
VC Fund
13 Japan, United States, China Series B, Series A Software, Health Care, Information Technology $11M–$330M
Osaka University Venture Capital
VC Fund
12 Japan Seed, Series A Health Care, Biotechnology, Manufacturing $6.9M–$233M
Real Tech Japan
VC Fund
9 Japan, Singapore, Austria Series A, Seed Manufacturing, Biotechnology, Robotics $4.8M–$233M
ANRI
VC Fund
8 Japan, United States, India Seed, Series A Health Care, Software, Information Technology $4.1M–$275M
SMBC Venture Capital
VC Fund
8 Japan, United States, Mexico Series A, Series B Health Care, Information Technology, Software $18M–$357M
Fast Track Initiative, Inc.
VC Fund
7 Japan, United States, United Kingdom Series B, Series A Health Care, Biotechnology, Medical $9.8M–$536M
SBI Investment
VC Fund
6 Japan, South Korea, United States Series B, Series A Financial Services, Information Technology, Software $5.9M–$302M
DBJ Capital
VC Fund
5 Japan, United States, Australia Series A, Seed Software, Internet, Biotechnology $1.5M–$151M
Japan Science and Technology Agency
VC Fund
5 Japan Series A, Series B Medical, Biotechnology, Health Care $4.1M–$275M
Keio Innovation Initiative
VC Fund
5 Japan Seed, Series A Medical, Health Care, Biotechnology $12M–$100M
Nippon Venture Capital
VC Fund
4 Japan, United States Series A, Seed Software, Health Care, Information Technology $6.8M–$112M
Incubate Fund
VC Fund
4 Japan, United States, India Seed, Series A Software, Information Technology, E-Commerce $500k–$165M
Mizuho Capital
VC Fund
4 Japan, United States, China Series A, Series B Information Technology, Software, Internet $7.8M–$343M
F-Prime Capital
VC Fund
4 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$135M
Eight Roads Ventures
VC Fund
3 United States, China, India Series B, Series A, Series C Software, Health Care, Information Technology $5.4M–$100M
KSP
VC Fund
3 Japan Series A, Series B Biotechnology, Health Care, Medical $18M–$102M
Nissay Capital
VC Fund
3 Japan, United States Seed, Series A Health Care, Internet, Medical $925k–$69M
Senshu Ikeda Capital
VC Fund
3 Japan Seed, Series A Software, Internet, Information Technology $5.6M–$89M
Future Venture Capital
VC Fund
3 Japan, United States, Myanmar Seed, Series A Information Technology, Manufacturing, Health Care $6.9M–$64M
Takeda Ventures
VC Fund
3 United States, United Kingdom, Israel Series A, Series B Biotechnology, Health Care, Therapeutics $8M–$100M
Takeda
VC Fund
3 United States, Japan, Canada Corporate Round, Series A Biotechnology, Health Care, Pharmaceutical $5M–$1.4B
Japanese Organization for Medical Device Development
VC Fund
2 Japan, United States Seed, Series A Biotechnology, Laser, Medical $2.1M–$82M
Japan Asia Investment
VC Fund
2 Japan, United States, China Series B, Series C Medical, Biotechnology, Health Care $5M–$275M
Innovation Network Corporation of Japan
VC Fund
2 Japan, United States Series B, Series A Manufacturing, Software, Robotics $5M–$357M
SPARX Group
VC Fund
2 Japan, United States, China Series B, Series A Software, Artificial Intelligence, Information Technology $11M–$412M
Fujifilm
VC Fund
2 Japan, Israel, United States Series A, Series B Biotechnology, Medical Device, Medical $49M–$412M
Fuyo General Lease
VC Fund
2 Japan Series A, Seed Biotechnology, Manufacturing, Sales $48M–$233M
Glocalink
VC Fund
2 Japan, Singapore Seed, Series A Health Care, Robotics, Task Management $687k–$8.3M
Remiges Ventures
VC Fund
2 United States, Japan, Canada Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $6.4M–$20M
Essential Pharma
VC Fund
2 Japan Series A Medical, Software, Life Science $37M–$76M
Media Future
VC Fund
2 Japan Series A Medical, Software, Life Science $37M–$76M
Tsukuba Institute of Research
VC Fund
2
Kyogin Lease & Capital
VC Fund
2 Japan Series A, Series B Manufacturing, Task Management, Medical $16M–$330M
JIC Venture Growth Investments
VC Fund
2 Japan, Singapore, Thailand Series B, Series C Software, Information Technology, Consulting $4.1M–$398M
UTokyo Innovation Platform
VC Fund
2 Japan, United States, United Kingdom Series A, Seed Biotechnology, Medical, Health Care $7.9M–$275M
SBI Group
VC Fund
2 Japan, United States, United Kingdom Series B, Series A Financial Services, FinTech, Software $2.9M–$137M
Ohara Pharmaceutical
VC Fund
2 Japan, Kenya, Nigeria Series A, Series B Medical, Biotechnology, Nursing and Residential Care $10M–$76M
Capital Medica Ventures
VC Fund
2 Japan Seed, Series A Medical, Software, Health Care $14M–$48M
CyberAgent
VC Fund
1 Japan, South Korea Series A, Seed Internet, Advertising, Education $111M–$137M
Eight Roads Ventures Japan
VC Fund
1 Japan, United States Series B, Series A Information Technology, E-Commerce, Virtual World
Resona Bank
VC Fund
1 Japan Debt Financing, Series A Information Technology, Education, Internet $9.6M–$165M
Energy & Environment Investment
VC Fund
1 Japan, United States, Germany Series A, Series B Internet of Things, Software, Energy $3.8M–$536M
Real Tech Holdings
VC Fund
1 Japan Seed Manufacturing, Software, 3D Printing $41M–$55M
Triple Ring Technologies
VC Fund
1 United States, Japan Seed, Corporate Round Biotechnology, Beauty, Robotics $3.4M–$4M
Daiichi Sankyo
VC Fund
1 Japan Series A Medical, Health Care, Therapeutics
ARCH Venture Partners
VC Fund
1 United States, China, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $7M–$230M
Yokohama Capital
VC Fund
1 Japan Series A, Series B Health Care, Artificial Intelligence, Task Management $25M–$96M
CAC CAPITAL
VC Fund
1 Japan, Malaysia, Thailand Series A, Seed Recruiting, Internet of Things, Internet $1.3M–$41M
Shoko Chukin Bank
VC Fund
1 Japan, Canada, Singapore Debt Financing, Series B Manufacturing, Education, E-Commerce $14M–$549M
Cosmo Bio
VC Fund
1 Japan Seed Medical, Biotechnology, Pharmaceutical
Access all 308 VC funds in Japan Biotechnology startups.

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Investor list

Mitsubishi UFJ Capital
VC Fund · Tokyo, Tokyo, Japan · 13 investments in Japan Biotechnology startups, 9 in the past 12 months

Mitsubishi UFJ Capital is a venture capital firm focusing on life science, ICT, and high technology investments.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series A
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 259
  • Round size: Series A $11M–$96M; Series B $12M–$330M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • LiLz — LiLz is an IT technology network for businesses looking to use AI and IoT to offer new services and value.
  • CADDi — CADDi is an online ordering platform for manufacturing industry.
  • EX-Fusion — EX-Fusion develops the first commercial laser based nuclear fusion reactor for power generation.
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Osaka University Venture Capital
VC Fund · Osaka, Osaka, Japan · 12 investments in Japan Biotechnology startups

Osaka University Venture Capital is a venture capital firm that focuses on early-stage ventures in the fields of life innovation, green innovation, and platform technology. The firm was founded in 2014 and based in Osaka, Japan.

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Investment focus

  • Industry: Health Care, Biotechnology, Manufacturing
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 62
  • Round size: Seed $6.9M–$48M; Series A $17M–$233M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: May invest from a new fund soon — last raise in 2021

Portfolio highlights

  • SK Fine — SK Fine is the first to develop a 3D printer for ceramics and release it to the market for the first time in Japan.In addition, we are using 3D ceramic printers to develop 3D ceramic parts molding processes that meet our needs.
  • EX-Fusion — EX-Fusion develops the first commercial laser based nuclear fusion reactor for power generation.
  • GAIA BioMedicine — GAIA BioMedicine Inc., a spin-out venture from Kyushu University founded on 2015, is a technology-driven biopharmaceutical company focusing on cellular therapies and immunotherapies mainly for intractable malignancies.
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Real Tech Japan
VC Fund · Sumida, Tokyo, Japan · 9 investments in Japan Biotechnology startups

Real Tech Japan is a venture capital firm that seeks to invest in innovative R&D technology companies. Realtech Fund is a joint venture between the Ministry of Economy, Trade, and Industry and NEDO (New Energy and Industrial Technology Development Organization). The firm was founded in 2014 and based in Tokyo, Japan.

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Investment focus

  • Industry: Manufacturing, Biotechnology, Robotics
  • Stage:Series A, Seed
  • Geography: Japan, Singapore, Austria

Investor stats

  • Total investments: 76
  • Round size: Seed $4.8M–$41M; Series A $6M–$233M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • ProfilePrint — ProfilePrint synthesises complex molecular data of ingredient samples into digital fingerprints, rapidly predicting its identity and quality, helping agribusinesses to buy and sell better with its patented digital food identity-as-a-service (IDaaS) technology.
  • Integriculture — Integriculture makes cellular agriculture products to improve sustainability, food security, and reduce public health problems. The company offers a developed patented general-purpose large-scale cell culture system that can culture wide range of cells without external addition of expensive growth factors and provide consumers with affordable cleanmeat.Founded in 2015, Integriculture is headquartered in Tokyo, Japan.
  • Sentient.io — We provide a secure AI & Data platform with ready-made AI models for easy adoption and turnkey AI solutions for Enterprises on your digitalisation journey.
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ANRI
VC Fund · Tokyo, Tokyo, Japan · 8 investments in Japan Biotechnology startups, 10 in the past 12 months

ANRI is a Japanese venture capital firm that mainly invests in seed and early-stage startups.

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Investment focus

  • Industry: Health Care, Software, Information Technology
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 155
  • Round size: Seed $4.1M–$47M; Series A $12M–$275M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • EX-Fusion — EX-Fusion develops the first commercial laser based nuclear fusion reactor for power generation.
  • YourTrade — YourTrade helps cross-border e-commerce companies to resale rejected goods and backlogged inventory from overseas sales through local sales channels.It also provides services such as collection and inspection of returned items, as well as resale through local sales channels.
  • Carnot — LLM, Autonomous Agent
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SMBC Venture Capital
VC Fund · Tokyo, Tokyo, Japan · 8 investments in Japan Biotechnology startups, 6 in the past 12 months

Sumitomo Mitsui Banking Corporation (SMBC) and its group companies offer a broad range of financial services centered on banking. They are also engaged in the leasing, securities, credit card, investment, mortgage securitization, venture capital and other credit related businesses. The following lists the activities of SMBC, its subsidiaries andaffiliates in the various business segments.

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Investment focus

  • Industry: Health Care, Information Technology, Software
  • Stage:Series A, Series B
  • Geography: Japan, United States, Mexico

Investor stats

  • Total investments: 309
  • Round size: Series A $18M–$165M; Series B $21M–$357M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
  • Luup — Luup is an Internet Company.
  • Kyoto Fusioneering — Kyoto Fusioneering is a research & development, design, and manufacture of parts related to fusion reactors.
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Fast Track Initiative, Inc.
VC Fund · Hongo, Tokyo, Japan · 7 investments in Japan Biotechnology startups

Fast Track Initiative is a venture capital firm with an exclusive focus on life sciences and healthcare services.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series B, Series A
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 40
  • Round size: Series A $9.8M–$137M; Series B $25M–$536M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: May invest from a new fund soon — last raise in 2021

Portfolio highlights

  • AIRNA — AIRNA is on a mission to transform the lives of patients with rare and common diseases by pioneering thediscovery and development of RNA editing therapeutics.
  • Storm Therapeutics — Targeting pathways that modify RNA to deliver novel cancer therapeutics.
  • Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
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SBI Investment
VC Fund · Minato, Chiba, Japan · 6 investments in Japan Biotechnology startups, 13 in the past 12 months

SBI Investment supports the business development and growth of private venture companies through fund investment.

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Investment focus

  • Industry: Financial Services, Information Technology, Software
  • Stage:Series B, Series A
  • Geography: Japan, South Korea, United States

Investor stats

  • Total investments: 232
  • Round size: Series A $6M–$179M; Series B $5.9M–$302M
  • Lead/follow: 18% lead, 82% follow
  • Last fund: May invest from a new fund soon — raised $1.1B in 2020

Portfolio highlights

  • Edgecortix — At Edgecortix, we automate the design of AI accelerators for on-device deep learning. Our Dynamic Neural Accelerator IP, and performance optimized AI Software & Hardware Co-exploration framework, reduces time to market and brings massive cost savings across multiple industry verticals.
  • Habito — We're the Treating Customers Fairly Champion of 2023 as voted for in the British Bank Awards. We're here to make mortgages easier - no paperwork, no stress and no fees.
  • Captain Fresh — Captain Fresh is a freshwater fish and seafood supply chain platform. Captain Fresh is a B2B marketplace leveraging technology to deliver the fastest harvest-to-retail in the industry. The company focuses on aggregating the fragmented retail demand across the country and linking them to the small fishermen and farmers throughout the Indian coast.The company was founded in 2019 and is based in Bengaluru, India.
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DBJ Capital
VC Fund · Otemachi, Tokyo, Japan · 5 investments in Japan Biotechnology startups, 6 in the past 12 months

DBJ Capital Co., Ltd. was founded in June 2010 through the integration of two venture capital firms of the DBJ Group, New Business Investment Co., Ltd. and Intellectual Properties Development & Investment, Inc. We are a wholly-owned subsidiary of Development Bank of Japan Inc.At DBJ Capital, we focus on venture firms which use newtechnologies and business models to grow and compete on the global market, regardless of their industry or scale. To meet the particular needs of each client, we mobilize the entire DBJ Group to arrange the best investment solutions, ranging from growth-spurring equity investment to financing schemes drawing on DBJ's vast networks.We also assist in venture start-ups. Our value enhancement team provides the kind of comprehensive, hands-on support needed to commercialize outstanding intellectual property and technologies developed by firms, research labs, and universities, and to carve out a place for them in the market.DBJ Capital will continue to play in a part in Japan's economic revival - by helping the firms we invest in to grow, and by encouraging the creation of new industries in Japan.

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Investment focus

  • Industry: Software, Internet, Biotechnology
  • Stage:Series A, Seed
  • Geography: Japan, United States, Australia

Investor stats

  • Total investments: 111
  • Round size: Seed $1.5M–$41M; Series A $16M–$151M
  • Lead/follow: 14% lead, 86% follow

Portfolio highlights

  • LexxPluss — LexxPluss develops an automatic transfer software system and robot hardware.
  • Cellusion — Cellular technology breakthrough for clear vision of the future.
  • Kyoto Fusioneering — Kyoto Fusioneering is a research & development, design, and manufacture of parts related to fusion reactors.
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Japan Science and Technology Agency
VC Fund · Tokyo, Tokyo, Japan · 5 investments in Japan Biotechnology startups

Japan Science and Technology Agency is an integrated organization of science and technology that implements science and technology policy in Japan.  It handles many projects, including the government’s Science and Technology Basic Plan and knowledge creation. The European Sustainability School ESSSR is the owner of Japan Science and TechnologyAgency.Japan Science and Technology Agency undertakes its task in a comprehensive manner. It also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.Japan Science and Technology Agency is headquartered in Tokyo, Japan.

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Investment focus

  • Industry: Medical, Biotechnology, Health Care
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 32
  • Round size: Series A $14M–$275M; Series B $4.1M–$12M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
  • bitBiome — BitBiome is a microbiome analysis company that aims to discover and understand disease-linked microorganisms. Its, single-cell whole-genome analysis platform specifically targets microbes and can be used on uncultured, raw samples, providing unprecedented strain-level quantitative and functional insights.THe company was founded in 2018 and isbased in Japan.
  • Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.
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Keio Innovation Initiative
VC Fund · Tokyo, Tokyo, Japan · 5 investments in Japan Biotechnology startups

Keio Innovation Initiative (KII) is a venture capital established by Keio University. In order to make more effective use of the research results of Keio University, we aim to contribute to the development of society by creating investment for venture companies that utilize research results and creating new industries.The key to thinking aboutJapan's future growth strategy is to utilize advanced research results of the university. In addition to GDP, in addition to GDP, Japan is the world's third largest R & D exporter in R & D expenses, but as the low growth rate shows, it has a problem in investment efficiency in research and development. There are also reports on the entrepreneurial spirit that is indispensable for creating new industries, with the lowest entrepreneurial activity rate among developed countries.

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Investment focus

  • Industry: Medical, Health Care, Biotechnology
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 43
  • Round size: Seed $12M–$55M; Series A $49M–$100M
  • Lead/follow: 21% lead, 79% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
  • Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
  • Nanofiber Quantum Technologies — Powering a globally connected quantum future with pioneering nanofiber cavity QED.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

Browse database — It's Free!
Nippon Venture Capital
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups

Nippon Venture Capital ("NVCC"), established in 1996 as one of the few largest Japanese independent venture capital firms, is destined to undertake the unprecedented task of providing full-range venture capital services in cooperation with major Japanese business leaders and leading companies, which have supported and nurtured various newbusinesses on their own, as well as proactively developing new venture enterprises.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series A, Seed
  • Geography: Japan, United States

Investor stats

  • Total investments: 124
  • Round size: Seed $6.9M–$112M; Series A $6.8M–$82M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Utill — Utill is anything that expands the possibilities of not only production but also our own services
  • LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
  • LUCA Science — LUCA Science develops innovative treatments intended for mitochondrial and related diseases.
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Incubate Fund
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups, 7 in the past 12 months

Incubate Fund is an independent early-stage venture capital that specializes in providing capital to technology startups at the seed stage. The firm built a portfolio of over 300 companies in Asia, taking 12 companies to public and 20 companies to M&A exit since 2010.

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Investment focus

  • Industry: Software, Information Technology, E-Commerce
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 180
  • Round size: Seed $500k–$45M; Series A $11M–$165M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: Likely still investing — raised $2.3B in 2021

Portfolio highlights

  • Cerby — Collaborate without chaos. Cerby helps your team be productive while protecting your brand. Secure unmanageable applications. Only with Cerby.
  • CYBO — CYBO provides products and services to understand cells deeply and to harness them widely.
  • Bondy — Bondy is an HR Tech automation platform that specializes in connecting different HR processes.
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Mizuho Capital
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups, 10 in the past 12 months

Mizuho is the venture capital firm affiliated to Mizuho Bank, the second-largest Japanese bank in terms of assets. The firm has headquarters in Tokyo.The firm has ¥49.6 billion JPY under management, focusing on information technology and biotechnology investments. Over 600 Mizuho companies have gone public. According to Nikkei, Mizuho is thefifth-largest venture capital firm in Japan.Mizuho Capital was formed in 2002 by the merger of Fujigin Capital, Tokyo Venture Capital and IBJ Investment. Three firms were subsidiaries of Fuji Bank, Dai-Ichi Kangyo Bank and the Industrial Bank of Japan respectively.

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Investment focus

  • Industry: Information Technology, Software, Internet
  • Stage:Series A, Series B
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 264
  • Round size: Series A $7.8M–$130M; Series B $25M–$343M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2020

Portfolio highlights

  • Funds — Funds is an online marketplace for lending funds.
  • Bloomo Investment — Bloomo Investment is a software company that specializes in the development of smart and fun investment apps.
  • LexxPluss — LexxPluss develops an automatic transfer software system and robot hardware.
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F-Prime Capital
VC Fund · Cambridge, Massachusetts, United States · 4 investments in Japan Biotechnology startups, 32 in the past 12 months

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 313
  • Round size: Series A $5M–$63M; Series B $13M–$135M; Series C $20M–$60M
  • Lead/follow: 27% lead, 73% follow

Portfolio highlights

  • Doceree — Doceree is a pharmaceutical advertising & healthcare marketing company which helps in getting a better healthcare services
  • Avalyn Pharma — This does NOT display on the home page
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
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Eight Roads Ventures
VC Fund · London, England, United Kingdom · 3 investments in Japan Biotechnology startups, 22 in the past 12 months

Eight Roads has a 50+ year history of investing and partners with game-changing technology and healthcare companies, supporting them as they scale to become global leaders.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, India

Investor stats

  • Total investments: 309
  • Round size: Series A $5.4M–$62M; Series B $7.3M–$100M; Series C $13M–$100M
  • Lead/follow: 43% lead, 57% follow
  • Last fund: Likely still investing — raised $350M in 2022

Portfolio highlights

  • Ketai Bio — Ketai Bio is a synthetic biology company dedicated to the R&D, production and sales of high value-added bio-based products.
  • New Vision Medical — New Vision Medical is an IT infrastructure service provider that offers clinical trial-related digital platforms and services.
  • Tenpoint Therapeutics — Tenpoint Therapeutics is a biotechnology company pursuing vision-restoring engineered cell-based therapeutics.
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KSP
VC Fund · Kawasaki, Kanagawa, Japan · 3 investments in Japan Biotechnology startups

KSP, Inc. is the core business entity responsible for operating the Kanagawa Science Park (KSP) and has accepted the challenge of creating new industries through the support, development, and incubation of venture businesses. We provide a variety of business support services that best meet the needs of venture businesses in each stage of theirbusiness growth, ranging from the processes of startup and growth to public offerings. Several hundreds of new startup companies have been created and nurtured since its foundation. An incubation manager (IM) acts as a coordinator and provides a variety of support services to a venture company to help them successfully launch and develop their new business, such as offering individual consultations and a variety of information or advice. KSP, Inc. is well poised to cope with the varying needs of new ventures for highly sophisticated, specialized tasks by offering a business school, business support center, business matching services, and investment funds.The public sector, such as the Kanagawa prefectural government, Kawasaki city government, and the Development Bank of Japan, Inc., has an equity participation in KSP, thus playing a vital role in the deployment of local industrial development policy.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 34
  • Round size: Series A $18M–$102M
  • Lead/follow: 6% lead, 94% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Metcela — Metcela Inc. is a pioneer biotechnology company founded in Japan. Metcela aims to be the first to commercialize biological products that heal damaged heart muscle to treat heart failure.
  • Mira Robotics — I found a great domain name for sale on Dan.com. Check it out!
  • Melody International Japan — Melody International Japan is a company that supports medical and health with ICT.
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Nissay Capital
VC Fund · Tokyo, Tokyo, Japan · 3 investments in Japan Biotechnology startups

Nissay Capital is a venture capital Company specializing in seed, start-up, growth capital, middle stage, and later stage investment.

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Investment focus

  • Industry: Health Care, Internet, Medical
  • Stage:Seed, Series A
  • Geography: Japan, United States

Investor stats

  • Total investments: 147
  • Round size: Seed $925k–$55M; Series A $14M–$69M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Todoker — Todoker is a baggage delivery convenient service providing company.
  • LUCA Science — LUCA Science develops innovative treatments intended for mitochondrial and related diseases.
  • Beer and Tech — Beer and Tech operates a website for the Phalaenopsis or foliage plant HitoHana. Norihisa Morita and Yoshiaki Ito founded it in 2014, with its headquarters in Saitama in Japan.
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Senshu Ikeda Capital
VC Fund · Osaka, Osaka, Japan · 3 investments in Japan Biotechnology startups

Senshu Ikeda Capital offers financial consultancy services.

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Investment focus

  • Industry: Software, Internet, Information Technology
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 47
  • Round size: Seed $5.6M–$59M; Series A $16M–$89M
  • Lead/follow: 6% lead, 94% follow
  • Last fund: May invest from a new fund soon — raised $165M in 2019

Portfolio highlights

  • Sagri — Sagri is developing agriculture software for experienced farmers.
  • BABY JOB — BABY JOB offers nursery support and child care support businesses.
  • On The Slope — On the way to Sakano deliver vegetables grown without the use of pesticides and chemical fertilizers, aiming to spread agriculture with low environmental impact. We want to make agriculture sustainable and reach a sustainable society.
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Future Venture Capital
VC Fund · Kyoto, Kyoto, Japan · 3 investments in Japan Biotechnology startups

Future Venture Capital Co., Ltd. is a venture capital firm specializing in early stage investment. The firm invests in diversified investment in a broad range of industrial sectors. It seeks to invest in Japan. The firm prefers to be the lead investor in its portfolio companies. Future Venture Capital Co., Ltd. was founded in 1998 and is based inKyoto, Japan with offices in Tokyo, Aomori, Iwate, Yamagata, Kanazawa, Mie, Sakai, Kobe, and Ehime.

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Investment focus

  • Industry: Information Technology, Manufacturing, Health Care
  • Stage:Seed, Series A
  • Geography: Japan, United States, Myanmar

Investor stats

  • Total investments: 108
  • Round size: Seed $6.9M–$17M; Series A $16M–$64M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Torana — Torana provides "Toysub!" well known as educational toy subscription service in Japan market. We plan to go global and will be more bigger market share holder in East Asia. We collect month-age base toy feedback data and children's development status information. We plan best combination of toys and deliver. Customer returns and getsnew toys which fit children's growth and it is eco friendly service. We plan to build our own brand toys based on massive customer feedback and growth data and enter D2C market.
  • LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
  • IGNITE IMPULSE, INC. — As a digital agricultural enhancing service, Ignite impulse offers a variety of services, some of which include the following: agricultural software and equipment rentals, sales, maintenance, and leasing solutions; self-regulated farm shells with pre-installed vertical farming solutions; machined irrigation consulting and installations; artificialintelligence (AI) powered farming solutions; hydroponics farming consultation- partnership and installations; supply chain and logistics partnership; and more.Ignite Impulse also offers hydroponics solutions, as well as controlled farming assistance and consulting, to corporate, government, and educational organizations as part of our cooperation with these entities.
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Takeda Ventures
VC Fund · San Diego, California, United States · 3 investments in Japan Biotechnology startups, 6 in the past 12 months

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 95
  • Round size: Series A $8M–$43M; Series B $11M–$100M
  • Lead/follow: 19% lead, 81% follow

Portfolio highlights

  • Cerevance — Cerevance is a developer of novel therapeutics intended to advance new medicines for serious neurological diseases.The company's therapeutics applies it's technology called NETSseq to reveal transcriptional and epigenetic differences between specific cell types in mature human brains, enabling healthcare providers to detect and tackle theearly onset of various neurological diseases.
  • OncoResponse — OncoResponse Inc., an immuno-oncology company located in Houston, Texas, has partnered with MD Anderson Cancer Center (MDACC) to deploy a unique and transformational approach to cancer therapeutic monoclonal antibody and target discovery. The company licensed the I-STAR™ platform, developed and validated by Theraclone Sciences of Seattle, tointerrogate the human memory B-cell repertoire of cancer patients who are considered “Elite Responders” to immunotherapy; as such, their own adaptive immune system responded to immunotherapy stimulation in a way that achieved curative or durable responses. From these Elite Responders, OncoResponse is leveraging the human immune system to identify fully human monoclonal antibodies and discover novel targets that will lead to the development of fully human antibody derived therapeutics for the treatment of cancer.
  • Larkspur Biosciences — Larkspur's strategy focuses on the particular ways in which tumours hijack the immune system by developing precision immunotherapies for molecularly defined patient groups to overcome the bottlenecks that allow the tumour to subvert the immune system.
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Takeda
VC Fund · Osaka, Osaka, Japan · 3 investments in Japan Biotechnology startups

Takeda is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Corporate Round, Series A
  • Geography: United States, Japan, Canada

Investor stats

  • Total investments: 34
  • Round size: Series A $5M–$165M; Corporate Round $52M–$1.4B
  • Lead/follow: 41% lead, 59% follow

Portfolio highlights

  • Ambys Medicines — Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies. Ambys Medicines is working to fundamentally transform the lives of people suffering from severe liver diseases by creating breakthrough therapies capable of restoring liver function, preventing the progression of liver disease,and treating the devastating complications of liver failure.
  • Crescendo Biologics — Crescendo Biologics is a new Cambridge-based company whose vision is to deliver next-generation antibody therapeutics based on novel class-leading platforms.The focus of the company is on developing platforms that will address key issues in generating high-affinity, soluble, human VH antibody fragments. These are the smallest fragments thatretain antibody binding, and have many desirable properties as potential therapeutics. Crescendo will then utilise these platforms for product development of in-house targets or in partnership with other companies.
  • Cardurion Pharmaceuticals — A Boston-based cardiovascular biotechnology company developing next-generation therapeutics for the treatment of heart failure and cardiovascular diseases.
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Japanese Organization for Medical Device Development
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

The Japan Medical Device Development Organization aims to activate Japan's medical innovation and medical device industry, centering on the medical device incubation business, and aim for Japan to become a world leader in this field.Japanese Organization for Medical Device Development is a country of craftsmanship, possesses high technicaland quality control skills, and should be good at producing medical equipment. However, in the medical device field, imports exceed 600 billion yen every year. Japan's “manufacturing” technology has not been fully utilized.

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Investment focus

  • Industry: Biotechnology, Laser, Medical
  • Stage:Seed, Series A
  • Geography: Japan, United States

Investor stats

  • Total investments: 6
  • Round size: Series A $2.1M–$82M
  • Lead/follow: 33% lead, 67% follow

Portfolio highlights

  • Luxonus — Luxonus is a product development of a new imaging device using optical ultrasonic technology.
  • Meltin MMI — Meltin MMI is a cyborg-technology company that focuses on biosensors and robotic arms. Meltin has successfully enabled fine finger movements, such as for amputees and participated in Cybathlon 2016 and won the Microsoft Innovation Award.
  • Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
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Japan Asia Investment
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

JAIC is Japan's largest independent venture capital firm and has accumulated experience and know-how over a period of 15 years as a pioneer of venture capital investments in Asia. Building on such strengths, they are establishing a globally linked organization that pursues investment opportunities centering on the three regions of Japan, Asia,and the United States.

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Investment focus

  • Industry: Medical, Biotechnology, Health Care
  • Stage:Series B, Series C
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 31
  • Round size: Series B $6M–$275M; Series C $5M–$32M
  • Lead/follow: 10% lead, 90% follow

Portfolio highlights

  • FacePeer — FacePeer is looking for people who want to challenge at startup.
  • REGiMMUNE — REGiMMUNE Corporation is a private biopharmaceutical company developing innovative solutions for treating immune disorders caused by nonspecific and/or excessive immune reactions. REGiMMUNE uses its proprietary technology platform, reVax (reverse vaccination), to target immune tolerance against specific disease-causing antigens throughinduction of regulatory T cells (Treg). This technology has potential applications in a number of immune system disorders and diseases including Graft versus Host Disease (GvHD), type 1 diabetes mellitus (T1DM), rheumatoid arthritis (RA), multiple sclerosis (MS) and systemic lupus erythematosus (SLE).Currently, the company has one clinical-stage compound in a Phase I/II trial in the United States (RGI-2001) as a treatment for GvHD associated with hematopoietic stem cell transplantation and has a second product in preclinical development (RGI-3001) as a new treatment for T1DM. In addition, it has a number of well-differentiated compounds in its research-stage pipeline.In healthy individuals, the normal immune system works to protect humans from disease-causing viruses, bacterium, and cancers; or foreign antigens such as peanuts, wheat and tree pollens. Conventional immunosuppressants have several significant side effects associated with long-term administration including risk of infection, toxicity and relapse. Products developed with ReVax technology are expected to reduce or eliminate such side effects as well as reduce long-term treatment.
  • Integral Geometry Science — Integral Geometry Science is a specialized manufacturer of measuring equipment and signal / image processing software.
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Innovation Network Corporation of Japan
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Innovation Network Corporation of Japan (INCJ) is a public-private partnership aimed at promoting innovation and enhancing value.Leveraging the rich history of Japanese technological prowess, INCJ aims to provide financial, technological and management support in order to promote the creation of next-generation businesses through “openinnovation,” or the flow of technology and expertise beyond the boundaries of existing organizational structures.INCJ will draw on funding as well as management and technological expertise from the public and private sectors. INCJ is actively reviewing various investment opportunities in areas of green energy, electronics, IT and biotechnology to infrastructure-related sectors such as water supply. Each investment will be thoroughly vetted to ensure it meets the exacting standards of INCJ's Innovation Network Committee, which will make the final investment decisions.INCJ is capitalized at 280 billion yen, with the Japanese government injecting 266 billion yen and 26 private corporations (refer to details in Appendix below) providing a further 14 billion yen. The government will also provide guarantees up to a total of 1,800 billion yen for INCJ investments, giving it an investment capability of approximately 2,000 billion yen. INCJ will be established for a period of 15 years.

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Investment focus

  • Industry: Manufacturing, Software, Robotics
  • Stage:Series B, Series A
  • Geography: Japan, United States

Investor stats

  • Total investments: 71
  • Round size: Series A $6M–$330M; Series B $5M–$357M
  • Lead/follow: 32% lead, 68% follow

Portfolio highlights

  • QUADRAC — QUADRAC is a develop, manufacture, and sell telecommunication devices as well as payment servers for public transportation systems. The company aims to improve user convenience through a variety of payment methods, and to contribute to the realization of a cashless society. QUADRAC's thin-client type high-speed server "Q-CORE" isable to consolidate all of the fare calculation, payment, and security functions carried out by train station ticket gates and payment.
  • ANYCOLOR — ANYCOLOR is an entertainment start-up that provides creator support and licensing business, mainly for the support and operation of virtual rivers participating in the “Nijisanji Project”. Using the latest technology, we will shape our thoughts on society as a new era of cutting-edge, and provide a magical experience to the everyday lives of peoplearound the world.
  • GRA Japan — GRA is a Production and sales and export of agricultural products company.
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SPARX Group
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

SPARX Group Co., Ltd. is an independent Asia-based equity and credit asset management services and Asian fund financial specialist with offices in Tokyo, Hong Kong and Seoul for global institutional and individual investors, including financial advisors and financial planners, with alternative strategies (including activist, short-enabled, private equity and quantitative and fund-of-funds) and mutual funds (through SPARX Asia Funds such as SPARX Asia Pacific Opportunities Fund, SPARX Asia Pacific Equity Income Fund, SPARX Japan Smaller Companies Fund and SPARX Japan Fund) managed or sub-advised by SPARX Asset Management Co. Ltd., SPARX Asia Investment Advisors Limited and Cosmo Asset Management Co., Ltd.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series B, Series A
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 69
  • Round size: Series A $11M–$330M; Series B $36M–$412M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Blue Laser Fusion — Blue Laser Fusion is a commercial fusion company. Blue Laser Fusion is a laser startup to commercialize laser fusion by inventing its own laser and fusion reactor.
  • UnaBiz — Based in Singapore, Taiwan and Japan, UnaBiz delivers end-to-end customised IoT solutions worldwide. Simple, cost-efficient & low maintenance
  • Nanofiber Quantum Technologies — Powering a globally connected quantum future with pioneering nanofiber cavity QED.
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Fujifilm
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Fujifilm develops and sells consumer products and business products related to photography. Fujifilm Holdings Corporation is a Japanese multinational photography and imaging company. The company serves various industries, including medical, graphic arts, optics, enterprise storage, motion picture, and photography.The company’s consumer productsare categorized as digital cameras and accessories, film photography, Instax photography, and binoculars. Its business products are categorized as medical systems, Fujinon endoscopy, microfilm, data storage, graphic arts and printing, professional video, optical devices, specialty chemicals, printing imaging colorants, and more. Color films, digital cameras, photofinishing equipment, color papers, photofinishing chemicals, medical imaging equipment, graphic arts equipment and materials, flat panel displays, and photocopiers and printers are some products developed by Fujifilm USA.Fujifilm USA is based in Minato-ku, Tokyo, Japan.

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Investment focus

  • Industry: Biotechnology, Medical Device, Medical
  • Stage:Series A, Series B
  • Geography: Japan, Israel, United States

Investor stats

  • Total investments: 10
  • Round size: Series A $49M–$412M
  • Lead/follow: 10% lead, 90% follow

Portfolio highlights

  • Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
  • Nanox Imaging — Nanox Vision develops a next-generation medical imaging system based on groundbreaking technology. Our aim is to democratize medical imaging and bring preventive healthcare to communities worldwide, helping create a better standard of care for all.
  • 24M Technologies — 24M Technologies develops energy storage systems for grid and transportation applications. 24M Technologies, Inc. builds energy storage systems for grid and transportation applications. The company was founded in 2010 and is based in Cambridge, Massachusetts.
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Fuyo General Lease
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Fuyo General Lease focuses in the leasing and installment sales trading of equipment and fixtures, and financial transaction. The company provides leasing services of information-related equipment, office equipment, and industrial equipment, installment sales of commercial facilities, production facilities, and hospital facilities. It also providessecurities management services and anonymous association composition.Fuyo General Lease was founded on 1969 and is headquartered in Tokyo, Japan.

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Investment focus

  • Industry: Biotechnology, Manufacturing, Sales
  • Stage:Series A, Seed
  • Geography: Japan

Investor stats

  • Total investments: 6
  • Round size: Series A $48M–$233M
  • Lead/follow: 17% lead, 83% follow

Portfolio highlights

  • ThinkCyte — ThinkCyte provides single-cell analysis for research, diagnostics, and therapeutics with an integrated multidisciplinary approach.
  • Tsubame BHB — Tsubame BHB is a Sales company
  • 3D Printing Corporation — 3D Printing Corporation provides 3D printing technology solutions.
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Remiges Ventures
VC Fund · Cambridge, Massachusetts, United States · 2 investments in Japan Biotechnology startups

Remiges Ventures is a venture capital firm that focuses on groups and businesses in the Japanese academia and pharmaceutical industry.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Japan, Canada

Investor stats

  • Total investments: 14
  • Round size: Series A $6.4M–$20M
  • Lead/follow: 71% lead, 29% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Immunis — Currently seeking participants for age-related muscle atrophy (sarcopenia) clinical trails
  • Kupando — Kupando is a biopharmaceutical company that develops agonists to stimulates innate immunity.
  • LUCA Science — LUCA Science develops innovative treatments intended for mitochondrial and related diseases.
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Essential Pharma
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Essential Pharma provided on this site is created for the purpose of providing information on our ethical drugs to medical professionals

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Investment focus

  • Industry: Medical, Software, Life Science
  • Stage:Series A
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Round size: Series A $37M–$76M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
  • HekaBio — HekaBio connects world-leading healthcare innovations to unmet medical needs in the Asia Pacific, with broad category development expertise in pharma, medical device, in-vitro diagnostics, digital health, and cell & gene therapies.
  • Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).
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Media Future
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Media Future is a group of communication technology professionals that works on connecting feelings and thoughts. The Tokyo, Tokyo-based company was established in 2013.

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Investment focus

  • Industry: Medical, Software, Life Science
  • Stage:Series A
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Round size: Series A $37M–$76M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
  • HekaBio — HekaBio connects world-leading healthcare innovations to unmet medical needs in the Asia Pacific, with broad category development expertise in pharma, medical device, in-vitro diagnostics, digital health, and cell & gene therapies.
  • Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).
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Tsukuba Institute of Research
VC Fund · Ibaraki, Osaka, Japan · 2 investments in Japan Biotechnology startups

Tsukuba Institute of Research (筑波総研) is an R&D center owned by housing and wood products group Sumitomo Forestry. The facility develops technologies to make more effective use of wood in a wide range of fields.

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Investor stats

  • Total investments: 5
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • FullDepth — FullDepth is a drone development company.
  • Alchemedicine — Alchemedicine is a the world in drug discovery with unique technologies and ideas Innovating new drug candidates for diseases with high unmet medical needs.
  • Veneno Technologies — Veneno Technologies engages in the research and development of therapeutic disulfide-rich peptides and contribute to advanced medicine.
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Kyogin Lease & Capital
VC Fund · Kyoto, Kyoto, Japan · 2 investments in Japan Biotechnology startups

Kyogin Lease & Capital is an investment firm that specializes in the leasing, stock and bond investment and public offering consulting.

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Investment focus

  • Industry: Manufacturing, Task Management, Medical
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 23
  • Round size: Series A $16M–$55M; Series B $37M–$330M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Thinca — Thinca is an IT system planning, development, and operations company that provides a cloud-based CTI (Computer Telephony Integration) hospitality & communication solution for corporate offices.
  • Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
  • Regional Fish — Regional Fish provides seed, seedlings, aquaculture methods and fisheries services.
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JIC Venture Growth Investments
VC Fund · Marunouchi, Tokyo, Japan · 2 investments in Japan Biotechnology startups, 7 in the past 12 months

JIC-VGI helps promote innovation and improve its international competitiveness through growth-investments in startup companies. The firm accelerating innovation and helping to solve industrial and social issues by supporting and seeking innovative technologies and new businesses.JIC Venture Growth Investments was established in July 2020 and isbased in Tokyo, Japan.

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Investment focus

  • Industry: Software, Information Technology, Consulting
  • Stage:Series B, Series C
  • Geography: Japan, Singapore, Thailand

Investor stats

  • Total investments: 37
  • Round size: Series B $4.1M–$385M; Series C $22M–$398M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • LiLz — LiLz is an IT technology network for businesses looking to use AI and IoT to offer new services and value.
  • Cellusion — Cellular technology breakthrough for clear vision of the future.
  • Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
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UTokyo Innovation Platform
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

The University of Tokyo IPC is a company responsible for expanding the innovation ecosystem of the University of Tokyo. Accelerate global innovation from the University of Tokyo through three activities: start-up support, investment business, and corporate innovation support.It was established as a wholly-owned subsidiary of the University ofTokyo in 2016 with the enforcement of the revised law of the Industrial Competitiveness Enhancement Law, which is the basis law. The investment targets of the Todai IPC are venture companies that utilize the research results and human resources of the University of Tokyo, but they also make FOF (fund of funds) investments in funds managed by some private venture capital companies. In 2019, it started a consortium-type incubation program (University of Tokyo IPC 1stRound) to support the establishment and financing of Tokyo University-related ventures.

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Investment focus

  • Industry: Biotechnology, Medical, Health Care
  • Stage:Series A, Seed
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 47
  • Round size: Seed $8.7M–$41M; Series A $7.9M–$275M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.
  • Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
  • Logomix Inc. — Logomix Inc is a mammalian cellular genome architect startup. Logomix proprietary platform, Geno-Writing™, technology integrates large-scale (Mb) human genome-writing technologies and providing genetically architected versatile human cells and/or downsized cells and microbes for drug development and cell & gene therapy area.Majority ofthe cell engineering companies are currently focused on optimization of gene clusters by automatic high throughput system however, Logomix’s Geno-Writing™ provides the required tools for dealing with mammalian or complex genomes. Logomix works with partners by providing new biology-based solutions to co-create business and social values on Geno-Writing™ platform Current Focus Area includes: 1. Human Health & Therapeutics 2. Biomaterials & Chemicals 3. Agriculture & EnvironmentLogomix has 11 ongoing collaborative research partnerships. Currently Logomix is specifically looking for industry partners to address unmet needs in neurodegenerative disease areas.
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SBI Group
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

SBI Group aims to become a corporate entity that provides a variety of one-stop financial services over the Internet now that two major events, the Financial Big Bang resulting from deregulation, and the Internet Revolution resulting from IT innovation, have radically transformed the financial industry.

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Investment focus

  • Industry: Financial Services, FinTech, Software
  • Stage:Series B, Series A
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 98
  • Round size: Series A $2.9M–$137M; Series B $2.9M–$137M
  • Lead/follow: 52% lead, 48% follow

Portfolio highlights

  • banco — BANCO offers fintech, digital banking, supply chain finance, and corporate financing services.
  • Zodia Custody — Zodia is an institutional crypto custodian enabling global institutions, corporations, and investors to realize the potential of the digital asset future.
  • My Zoi Financial Inclusion Technologies — My Zoi Financial Inclusion Technologies is a financial company that offers financial inclusion for banked and unbanked firms.
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Ohara Pharmaceutical
VC Fund · Koka, Shiga, Japan · 2 investments in Japan Biotechnology startups

Ohara Pharmaceuticals is a pharmaceutical business involved in the development, manufacture, and distribution of pharmaceutical products.

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Investment focus

  • Industry: Medical, Biotechnology, Nursing and Residential Care
  • Stage:Series A, Series B
  • Geography: Japan, Kenya, Nigeria

Investor stats

  • Total investments: 9
  • Round size: Series A $10M–$76M
  • Lead/follow: 11% lead, 89% follow

Portfolio highlights

  • HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
  • Helium Health — Helium Health empowers healthcare providers in Africa with digital tools, financing solutions, and data partnerships. Learn more about our innovative solutions.
  • Revital Healthcare — Revital revolutionizes healthcare by bringing advancedmedical devices, including WHO-Prequalified syringes, meeting the healthcare needs of Africa and beyond.
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Capital Medica Ventures
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Capital Medica Ventures is a venture capital firm based in Tokyo, Japan with a focus on startups in the healthcare industry.Capital Medica Ventures is a venture capital that operates a venture fund specializing in the healthcare field. It is the only healthcare-specialized VC in Japan that can provide 30 medical institutions as a business trialfield.

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Investment focus

  • Industry: Medical, Software, Health Care
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 7
  • Round size: Seed $14M–$16M; Series A $22M–$48M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • HCMJ — HCMJ specializes in software development in the medical industry.
  • Epigno — Epigno provides hospital management systems for medical institutions.
  • Rehab for JAPAN — Rehab for Japan is developing a special rehabilitation SaaS for day service .
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CyberAgent
VC Fund · Tokyo, Tokyo, Japan · 1 investments in Japan Biotechnology startups

CyberAgent, Inc. is mainly engaged in the integrated net business.The Company operates in five business segments. The Integrated Net Business segment is engaged in the advertisement agency business, the smart phone media business, as well as the sale of advertisements for smart phone. The Media Related segment is engaged in the social gamebusiness, the operation of mobile media and personal computer business. The Ameba Related segment is engaged in the operation of Websites Ameba and Ameba Pigg.

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Investment focus

  • Industry: Internet, Advertising, Education
  • Stage:Series A, Seed
  • Geography: Japan, South Korea

Investor stats

  • Total investments: 12
  • Round size: Series A $111M–$137M
  • Lead/follow: 15% lead, 85% follow

Portfolio highlights

  • AWL — AWL is a company that provides the leading edge AI camera solutions company .
  • DiNA — CLOUD SERVICE SUPPORT
  • Payme Japan — Payme provides a platform for mobile payments to help users in Japan.
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Eight Roads Ventures Japan
VC Fund · Tokyo, Tokyo, Japan · 1 investments in Japan Biotechnology startups

Eight Roads has a 50+ year history of investing and partners with game-changing technology and healthcare companies, supporting them as they scale to become global leaders.

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Investment focus

  • Industry: Information Technology, E-Commerce, Virtual World
  • Stage:Series B, Series A
  • Geography: Japan, United States

Investor stats

  • Total investments: 7
  • Lead/follow: 57% lead, 43% follow
  • Last fund: May invest from a new fund soon — raised $3.4B in 2017

Portfolio highlights

  • oVice — oVice is a virtual spatial platform that allows people to gather in one place, move, talk, and collaborate freely as avatars. With the mission of “maximizing effective online communication”, oVice develops and provides lifelike features that offer users a close-to-reality interactive online experience. Featuring customization, you can change thelayout to match the theme of your usage, build lockable rooms, place down static objects, and more!Use it as a remote office, an event venue, an academic conference hall, and even a space for parties!
  • Payke — Payke Multicomponent is an application that allows to view all the information of products in their mother tongue.The application "Payke" makes it possible to connect products around the world to the Internet by utilizing the bar codes that are scattered throughout the world. the company's goal is to build an enormous database basedon barcodes. It is to reorganize and organize products around the world into a single database and allow anyone to freely access there. Anytime, anywhere, anyone will be able to touch the information of products around the world.
  • Asobica — Play is enthusiasm.At one time, card games and Pokemon, which were addicted to childhood, were just enthusiasm for us.It's fun and exciting to forget the time when you're crazy.Let's make a sigh that can be such an enthusiasm. Create a product that produces enthusiasm. Enthusiasm to the world."Asobica Innovation to theworld"Asobica is a company that evolves boring things and old industries using technology and the power of the Internet (Asobica).
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Resona Bank
VC Fund · Osaka, Osaka, Japan · 1 investments in Japan Biotechnology startups

Resona Bank provides various banking products and services for individual and corporate customers in Japan.

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Investment focus

  • Industry: Information Technology, Education, Internet
  • Stage:Debt Financing, Series A
  • Geography: Japan

Investor stats

  • Total investments: 35
  • Round size: Series A $38M–$151M; Debt Financing $9.6M–$165M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • Edge Japan — EDGE operates restaurant and wedding businesses.
  • Fairy Devices — Fairy Devices is providing multilingual speech translation engine for station guidance robots.
  • Japan Platform of Industrial Transformation — Japan Platform of Industrial Transformation is providing equity investment and business management services for affiliated group companies.
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Energy & Environment Investment
VC Fund · Higashi-shinagawa, Tokyo, Japan · 1 investments in Japan Biotechnology startups

Energy & Environment Investment, Inc. (EEI) is Japan’s first venture capital specialized in the clean technology sector. With core members who have rich hands on experience in founding and managing venture companies, we aim to provide risk money and various strategic values to promising venture companies and businesses.

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Investment focus

  • Industry: Internet of Things, Software, Energy
  • Stage:Series A, Series B
  • Geography: Japan, United States, Germany

Investor stats

  • Total investments: 71
  • Round size: Series A $3.8M–$206M; Series B $7.6M–$536M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: May invest from a new fund soon — raised $137M in 2019

Portfolio highlights

  • Astroscale — Astroscale is the first private company with a vision to secure the safe and sustainable development of space for the benefit of future generations, and the only company solely dedicated to on-orbit servicing across all orbits.
  • Synspective — Synspective provides one-stop-solutions by satellite gathered geospatial data. The core technology was developed by the ImPACT program led by The Cabinet Office, Government of Japan, building small SAR satellites and constellations, allowing frequent observation of areas of interest (AOI). Synspective uses its satellites to produce SAR data which can be provided to both government and commercial clients as-is, as well as transform that data through AI solutions to produce insights and user-friendly information across industries.
  • Clean Energy Connect — Clean Energy Connect is into offering green energy solutions. It invests in its own generation capacity for a stable electricity supply by not harming nature.
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Real Tech Holdings
VC Fund · Sumida, Tokyo, Japan · 1 investments in Japan Biotechnology startups

Real Tech Holdings is an R&D-based innovative technology that specializes in social implementation.

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Investment focus

  • Industry: Manufacturing, Software, 3D Printing
  • Stage:Seed
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Round size: Seed $41M–$55M
  • Lead/follow: 80% lead, 20% follow

Portfolio highlights

  • ExtraBold — ExtraBold specializes in the development of 3D printers.
  • Ark Edge Space — Ark Edge Space provides design, manufacturing & operational services for micro-satellites along with software solutions and consulting.
  • Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.
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Triple Ring Technologies
VC Fund · Newark, California, United States · 1 investments in Japan Biotechnology startups

Triple Ring Technologies is an on-demand core technology and product creation lab serving partners in regulated industries. They have successfully completed over 300 projects for confidential clients. Triple Ring has technology creation facilities in Silicon Valley and Boston.Their headquarters (Newark, CA) is 96,000 sq. ft. of flexible spacethat includes laboratories for electronics, optics, radiation source development, mechanical prototyping; systems integration, client drop-in offices; and pilot manufacturing. They build regulated technologies and complex products and offer a full range of related technical and business services: analysis and creation of intellectual property; development and implementation of technology strategy; design and development of engineering prototypes and released products; feasibility studies and testing; due diligence and situation analysis; and advisory services on regulatory compliance and technology pathways. Above all, they work collaboratively to build novel technologies and products.

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Investment focus

  • Industry: Biotechnology, Beauty, Robotics
  • Stage:Seed, Corporate Round
  • Geography: United States, Japan

Investor stats

  • Total investments: 4
  • Round size: Seed $3.4M–$4M
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • P-Mind — P-Mind is a research and development of a device that promotes production of sputum neurotrophic factor-like substances. P-Mind aim to establish a non-invasive treatment method using brain cells derived from mouse embryos.
  • LUUM — LUUM is introducing automation to the beauty-services market, initially focusing on eyelash extensions, a widely popular treatment ($20B global market opportunity). Pioneering a patented combination of robotics, AI, and machine vision, LUUM applies a full set of eyelash extensions in 20 minutes (instead of 2 hours), while eliminating the costsand safety risks associated with human application.
  • AiM Medical Robotics — We Think in Real Time.
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Daiichi Sankyo
VC Fund · Parsippany, New Jersey, United States · 1 investments in Japan Biotechnology startups

Daiichi Sankyo Company, Limited engages in the research, development, manufacture, import, sale, and marketing of pharmaceutical products. The company offers prescription drugs, OTC drugs, and quasi-drugs. Its principal products include Olmetec, Rezaltas, Calblock, and Mevalotin for cardiovascular diseases; Cravit for infectious diseases; Loxoninfor bone/joint diseases; and Urief for urological diseases. The company also offers vaccines. In addition, the company is developing products for various diseases, which are under various clinical trial stages. Further, it manufactures and sells cosmetics, medical equipment, food, and beverages, as well as veterinary medicines; and manufactures active pharmaceutical ingredients and intermediates. Daiichi Sankyo primarily operates in Japan, North America, Europe, and India. The company is headquartered in Tokyo, Japan.

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Investment focus

  • Industry: Medical, Health Care, Therapeutics
  • Stage:Series A
  • Geography: Japan

Investor stats

  • Total investments: 2
  • Lead/follow: 50% lead, 50% follow

Portfolio highlights

  • Cuorips, Inc. — CUORiPS is a company developing new medical care based on world's cutting-edge technology originated in Japan.
  • SymBio Pharmaceuticals — SymBio Pharmaceuticals Limited operates as a biopharmaceutical company. It offers Symbenda medicine for treating low-grade non-Hodgkin's lymphoma and chronic lymphatic leukemia in Singapore. The company was founded in 2005 and is headquartered in Tokyo, Japan.
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ARCH Venture Partners
VC Fund · Chicago, Illinois, United States · 1 investments in Japan Biotechnology startups, 22 in the past 12 months

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, Canada

Investor stats

  • Total investments: 303
  • Round size: Series A $7M–$100M; Series B $14M–$230M; Series C $12M–$104M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — raised $3B in 2022

Portfolio highlights

  • AIRNA — AIRNA is on a mission to transform the lives of patients with rare and common diseases by pioneering thediscovery and development of RNA editing therapeutics.
  • Generate Biomedicines — Generate Biomedicines is a biotechnological company focusing on creating breakthrough medicines.
  • Lightcast Discovery — Flexible control over droplet number, occupancy, location and movement. Enabling efficient, multi-step workflows with unprecedented flexibility.
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Yokohama Capital
VC Fund · Yokohama, Kanagawa, Japan · 1 investments in Japan Biotechnology startups

Yokohama Capital as a venture capital firm conducts investment and rehabilitation support for small and medium-sized companies.

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Investment focus

  • Industry: Health Care, Artificial Intelligence, Task Management
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 19
  • Round size: Series A $25M–$82M; Series B $65M–$96M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • GEXVal — GEXVal is to help patients and families fighting against orphan and intractable diseases
  • Fairy Devices — Fairy Devices is providing multilingual speech translation engine for station guidance robots.
  • Knowledge Palette — Knowledge Palette is a start-up company that conducts business of regenerative medicine cells.
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CAC CAPITAL
VC Fund · Tokyo, Tokyo, Japan · 1 investments in Japan Biotechnology startups

CAC Capital is a multi-strategy corporate venture capital. It pursues absolute fund returns through diversified investments and flexible allocations to venture companies with high growth potential.Supporting the Group's open innovation through means such as support for growth and collaboration of investee venture companies through hands-onin management, marketing, finance, and operations.In addition, aiming to realize high performance as a fund, we will operate a “multi-strategy” type fund that aims to achieve absolute profits by utilizing advanced management strategies and managing and managing portfolios.

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Investment focus

  • Industry: Recruiting, Internet of Things, Internet
  • Stage:Series A, Seed
  • Geography: Japan, Malaysia, Thailand

Investor stats

  • Total investments: 13
  • Round size: Seed $1.3M–$4.1M; Series A $1.5M–$41M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • GIZTIX — GIZTIX is an integrated logistics platform, solving problems on speed & fragmented processes of truck sourcing and also managing their own fleets that cause unscalable deliveries. GIZTIX enables businesses to outsource trucks in seconds to they can fulfil deliveries in time and also helping fleet owners to increase efficiency by providing TMSsoftware. Ultimately, GIZTIX will be the winner of trucking market by expanding fleets & customers networks and having largest & most active TRUCKING BIG DATA.
  • Tsukulink — Tsukulink is a job match matching platform for Japan’s construction industry.
  • Wired Beans Inc. — Wired Beans Inc. supports basic manufacturing stages using novel information technologies. It was founded on October 13, 2009, and is based in Tokyo, Japan.
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Shoko Chukin Bank
VC Fund · New York, New York, United States · 1 investments in Japan Biotechnology startups

Shoko Chukin Bank is a financial company offering personal banking services.

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Investment focus

  • Industry: Manufacturing, Education, E-Commerce
  • Stage:Debt Financing, Series B
  • Geography: Japan, Canada, Singapore

Investor stats

  • Total investments: 37
  • Round size: Series B $124M–$151M; Debt Financing $14M–$549M
  • Lead/follow: 11% lead, 89% follow

Portfolio highlights

  • Luup — Luup is an Internet Company.
  • SORABITO — SORABITO is an eCommerce marketplace for used construction equipment and machinery.
  • Synspective — Synspective provides one-stop-solutions by satellite gathered geospatial data. The core technology was developed by the ImPACT program led by The Cabinet Office, Government of Japan, building small SAR satellites and constellations, allowing frequent observation of areas of interest (AOI). Synspective uses its satellites to produce SAR data which can be provided to both government and commercial clients as-is, as well as transform that data through AI solutions to produce insights and user-friendly information across industries.
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Cosmo Bio
VC Fund · Tokyo, Tokyo, Japan · 1 investments in Japan Biotechnology startups

Cosmo Bio provides the most up-to-date products and technical information available from world-class manufacturers, to laboratories, research institutes, life-science education and testing organizations throughout Japan and around the world. They are proud that their ability to supply a vast array of products and information allows us to serve theneeds of all of their customers. By making full use of their international network, coupled with the highest quality information, they support the life sciences community with a level of commitment and responsibility befitting a company that is trusted by its valued customers.

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Investment focus

  • Industry: Medical, Biotechnology, Pharmaceutical
  • Stage:Seed
  • Geography: Japan

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Fimecs — FIMECS is a protein degradation technology-based drug discovery biotech focused on developing first-in-class protein degradation therapeutics for cancers and other difficult-to-treat diseases. The human body is comprised of at least 18,097 proteins.It has been revealed that 1,500 of them are related to certain diseases, nevertheless only about 300proteins have been regarded as druggable targets by small molecule drug discovery and all the rest have been undruggable.
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Biotechnology VC funding in Japan at a glance

Stats across 249 deals from 308 investors.

308
investors
in Japan Biotechnology startups
249
deals
in Japan Biotechnology startups
$41M
median round
in Japan Biotechnology startups
23%
lead investors
lead at least one round
20%
Seed
most common funding stage

Access all 308 VC funds in Japan Biotechnology startups.

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