Top 50 Software Startup Investors in Panama (May 2026)

Portfolio highlights

• 37xDubai — 37xDubai is a space where Art and Technology come together to create the most unique expressions of creativity.
• Avalon — Avalon is an Orlando, Florida-based platform to create games and virtual experiences.
• CryptoSimple — CryptoSimple is a roboadvisor-based crypto investing solution that is simple, smart and secure, without the crypto lingo.

Portfolio highlights

• t3rn — t3rn is a hosting platform for smart contracts, that enables trustless, interoperable, multi-chain execution and composable collaboration.
• Sumi Network — Sumi Network is a decentralized storage solution provider.
• Tanssi Network — The Tanssi Network is a permissionless appchain infrastructure protocol designed for swift and effortless deployment of application-specific blockchains.

Portfolio highlights

• Mara — Secure and easy to use crypto wallet, where you can buy, sell, earn, send or withdraw your fiat and crypto assets - including Bitcoin, Ethereum and Mara Token
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• t3rn — t3rn is a hosting platform for smart contracts, that enables trustless, interoperable, multi-chain execution and composable collaboration.
• Few and Far — Few and Far is the next-generation platform for experiences in Web3, including NFTs, DeFi, gaming, and more. They help NFT projects with launchpad services, minting tools, outbound marketing, and more. They offer creators the liquidity, ability to earn, and listings alongside the top collections on NEAR.
• Gameta — Gameta is a web3 company.

Portfolio highlights

• IronMill — IronMill is a Web3 infrastructure provider that focuses on offering customized integration solutions to program developers.
• GamePhilos — GamePhilos is to offer player digital ownership to mobile strategy games.
• Buidler DAO — Buidler DAO describes itself as a "network of web3 projects and talents." The effort brings together developers, researchers, and operators with the goal of providing an infrastructure and accelerator for cryptocurrency ventures.

Portfolio highlights

• Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
• GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
• Snackclub — Learn more about play to earn games

Portfolio highlights

• Clozer — Sell experiences & run gamified giveaways to grow your music streams
• move.ai — Move.ai provides motion capture platforms and tools to enable augmented and extended reality productions using AI and computer vision.
• SupraOracles — We're supercharging oracles to provide blockchains better, faster, accurate, and more secure off-chain data.

Portfolio highlights

• Web3Go — Web3Go is a blockchain startup that provides data tools powered by artificial intelligence.
• MetaZone — MetaZone's mission is to harness and expand the application layer of the metaverse to onboard a billion citizens. MetaZone is the first content distribution platform designed to facilitate the open digital economy. At its core, creators submit Metaverse Enabled Tokenized Applications (METAs) to the marketplace, allowing anyone to own,experience, and deploy them to any virtual world. Anyone connected to the platform can host high-quality functional 3D content on digital lands with the click of a few buttons.
• Utopia Labs — Trusted by leading DAOs to streamline operations, manage payroll, and consolidate financial reporting.

Portfolio highlights

• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• EBR Systems — EBR Systems, Inc. is an early-stage development venture pursuing novel approaches in cardiac rhythm management. EBR Systems develops devices for the treatment of cardiac arrhythmias.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Sortium — Sortium is your AI-powered production team, just a prompt away. Tap into our dynamic AI & Web3 platform to craft professional assets in real time using natural language. Generate exceptional content, streamline tokenization, and simulate economics and behavior. Experience the industry-standard output you deserve for all your game and virtual productions.
• ECSA — ECSA / BRLe Stablecoin - On/Off for Brazilian Reais
• Franklin — Hybrid cash & crypto payroll

Portfolio highlights

• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• Shiden Network — Shiden Network is a multi-chain decentralized application layer on Kusama Network. Kusama Relaychain does not support smart contract functionality by design - Kusama Network needs a smart contract layer. This is where Shiden Network comes in. Shiden supports Ethereum Virtual Machine, WebAssembly, and Layer2 solutions from day one. The platform supports various applications like DeFi, NFTs and more.

Portfolio highlights

• Metaloop — Metaloop is a scrap trading company that helps businesses from the metal recycling industry to boost revenue without scaling.
• Florida Street — PIXEL GG INC.
• Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.

Portfolio highlights

• Stems Labs — community and platform for collaborative creativity
• Thirdverse — Thirdverse (formerly known as Yomuneco Inc) is engaged in Virtual Reality content and services planning, development, sales and management.
• Avalon — Avalon is an Orlando, Florida-based platform to create games and virtual experiences.

Portfolio highlights

• Axoni — Axoni is a New York-based capital markets technology firm that specializes in distributed ledger infrastructure. Product offerings include blockchain deployments, large-scale data management, bespoke smart contract development, analytics services, and connectivity tools.
• AlloyX — AlloyX makes it simple and accessible for protocols, DAOs, and institutional investors to create diversified RWA investment strategies. We provide lenders with a flexible and efficient platform for managing all of their RWA assets based on their yield, risk, and liquidity preferences.
• Coinflow Labs — Coinflow is a payment solution that allows Web3 companies to accept traditional payment methods and payout their customers by converting cryptocurrency to USD in their traditional bank account.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• Shippify — Shippify is an innovative logistics service that connects businesses with a diverse network of drivers & 3PLs to provide same day delivery . Shippify is backed by strategic leading venture capital and angel investors. Currently available in Brasil, Mexico, Chile and Ecuador. The company was founded in 2014.

Portfolio highlights

• Duetti — Duetti acquires music catalogs from independent artists a-la-carte with transparent, data-driven deals. Fund your career and breathe new life into tracks with uniquely intelligent marketing. Partner with us one track at a time, or even just a percentage of one.
• Togather — Create your event on Togather, the UK's most trusted events booking platform, choose from our roster of over 1,500 of the best and most passionate creators...
• Magrathea — Magrathea Metals is a mining company that unlocks centuries of growth in human civilization by reducing the socioenvironmental impacts.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• PropertyScout — PropertyScout is a proptech startup that builds an end-to-end rental and sale platform for owners, agents, buyers, and tenants. The startup is connecting over 1,800 agents and agencies with buyers, renters, and owners, servicing thousands of satisfied customers every month. PropertyScout leverages its database of more than 200,000 properties, itstechnology platform, and its centralized operations to digitize and automate 90% of the real estate transaction. This frees up agents’ time to professionally and efficiently communicate with buyers, renters, owners and co-agents to deliver outstanding service and close transactions faster. Providing a transparent and trusted experience, PropertyScout has quickly become the favorite go-to place for buying, selling, and renting real estate in Thailand, as proven by hundreds of five-star reviews.

Portfolio highlights

• Bitcoin.com — The world's gateway to Bitcoin & cryptocurrency. Buy, sell, spend, swap, and invest in BTC, ETH, BCH, AVAX, MATIC & hundreds more digital assets. Stay informed about crypto, DeFi, and Web3.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Minterest — Minterest is a cross-chain decentralized money market lending protocol for decentralized financial. Its unique design attracts and rewards long-term liquidity with Minterest distributing value captured by the protocol to MNT token holders who actively participate in its governance. Minterest was founded in 2020 and is based in Tallin, Estonia.

Portfolio highlights

• Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
• Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Starbots — Starbots is the first-ever robot battle NFT game where players gain GEAR tokens through strategically assembling their own robots, winning battles, completing missions, and conquering new lands.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Project SEED — Project Seed is an one-stop blockchain gaming ecosystem that accelerates mass-adaption.

Portfolio highlights

• SuiPad — SuiPad is an IDO&INO platform, with selected projects, flexible whitelist, and fair level as the core positioning.
• Aperture — Aperture is a DeFi cross-chain investment ecosystem.
• Sandstorm — Sandstorm platform connects brands with the best metaverse builders.

Portfolio highlights

• Swaap — We build the market-neutral AMM protocol.
• AnotherBall — AnotherBall = Digital + Entertainment + Token economy
• RedStone — RedStone delivers frequently updated, reliable and diverse data for your dApp and smart contracts.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Xion Finance — Xion Finance is the easiest way to start earning a passive income on your crypto. Earn interest, shop products or yield farm with a novel one click to DeFi protocol. Get Started Today!
• Radom — A Decentralised Network for Coordination of Cloud Applications and Connected Assets

Portfolio highlights

• KYVE — Enabling limitless scalability for Web3.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Datachain — Datachain enables data from around the world to be connected securely by blockchain. Our blockchain interoperability solutions connect public and permissioned blockchains as well as traditional systems.

Portfolio highlights

• Hawksight.co — Maximize your gains on Solana DeFi with Hawksight's self-custodial & yield-optimized strategies
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Ajuna Network — Ajuna Network is a decentralized ecosystem for gamers and creators.

Portfolio highlights

• Outer Ring — Embark on an epic journey through galaxies. Explore, combat and forge your own legend.
• Infinity Arena — The place to connect players who love tactical card games or have passionate about collecting valuable and rare NFT cards.
• Ancient Kingdom — Ancient Kingdom is the first ancient martial arts game on the blockchain platform, pioneering the realization of real-time games on the blockchain platform.

Portfolio highlights

• Portal — Portal is a financial services company that trades crypto anywhere without putting coins at risk, all from within a controllable wallet. Founded in 2018, Portal is headquartered in San Francisco, California.
• ShapeShift — The all-new ShapeShift is your complete crypto management platform: send, receive, trade, track, and hodl bitcoin and other major cryptos. Hardware-secured. Non-custodial. Sign up today.
• Monarch Wallet — Monarch offers mobile and desktop apps, a decentralized wallet and exchange, a portfolio tracker, and universal KYC integration.

Portfolio highlights

• GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
• Pixion Games — Pixion Games is a studio focused on building competitive esports games for mobile device.
• Portals — Portals is a #DeFi yield and protocol aggregator for transaction bundling, any-to-any swaps, and real-time data

Portfolio highlights

• Hydraverse — Hydraverse is a metaverse dragon fighting game developer, focusing on the development of a PVP dragon fighting game software.
• Outer Ring — Embark on an epic journey through galaxies. Explore, combat and forge your own legend.
• Vee Finance — Bridge the gap between traditional banking and crypto Defi Earn fixed/flexible return on deposited assets

Portfolio highlights

• DAM — DAM is a protocol for creating purchasing power from cross-chain token portfolios through dPRIME, a Dotsama-based stablecoin.
• Bware Labs — Bware Labs provides an interface between Blockchain APIs consumers and node providers with integrated payment options and verified reliability, all embedded within our platform and protocol service.
• Altitude — Actively managed collateralised loans

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Xion Finance — Xion Finance is the easiest way to start earning a passive income on your crypto. Earn interest, shop products or yield farm with a novel one click to DeFi protocol. Get Started Today!
• QANplatform [QAN blockchain platform] — QANplatform is the quantum-resistant Layer 1 hybrid blockchain where developers can code web3 solutions in any language on top of the QAN blockchain platform.

Portfolio highlights

• Nillion — The Secure Processing Layer of Web3
• The Unfettered — The Unfettered is a blockchain PC game.
• Cryption Network — Cryption Network is crypto company. Its can swap, farm, Invest and predict with cryption's unique and user-friendly DeFi 2.0 products. Bringing mass adoption to DeFi. PolyDEX is cryption's flagship product, which is completely gasless, instant, cross-chain AMM DEX with yield farming.

Portfolio highlights

• GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
• GoldLink — GoldLink is a decentralized, on-chain undercollateralized lending protocol utilizing a novel and modular lending architecture to offer borrowers powerful, sophisticated investment strategies beyond anything offered in the space today.
• Optix — Optix is ​​a multi-chain option protocol service provider.

Portfolio highlights

• Shardeum — Shardeum is an EVM-based, linearly scalable smart contract platform that maintains low gas fees while providing true decentralization and solid security
• SithSwap — SithSwap is a next-gen AMM on StarkNet featuring instant volatile and stable swaps with ultralow slippage, near-zero fees, and the full security of Ethereum.
• FLUID — FLUID is the AI quant-based liquidity aggregator providing best execution for CeFi and DeFi at ultra-low latency.

Portfolio highlights

• DAOLaunch — DAOLaunch is a decentralized platform that connects investors and startups directly on the blockchain by introducing innovative fundraising solutions to the startup ecosystem. Users can effortlessly create and support new startups across all borders, and participate in transparent, flexible and fair financing rounds regardless of a project being a crypto or fiat.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• Yuno — A fast checkout that integrates your company to the payments and fraud ecosystem.
• Bia Energy — Bia Energy engages in energy marketing.

Portfolio highlights

• Sidus Heroes — gaming company
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.
• CryptoVsZombie — CryptoVsZombie is the ultimate crypto tower defence in which players are required to multitask in both offensive and defensive modes.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Amyl Therapeutics — Amyl Therapeutics is a preclinical stage biotechnology company. Amyl Therapeutics uses a novel mechanism to bind to the amyloid fold of toxic protein aggregates of various types, including antibody light chain (AL) or transthyretin (TTR) aggregates, which accumulate in peripheral organs to cause systemic amyloidosis diseases, but also amyloid-β(Aβ), Tau, and α-synuclein aggregates, which accumulate in the brain to cause Alzheimer's and Parkinson's diseases.

Portfolio highlights

• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Portfolio highlights

• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Wicrypt — Wicrypt is a dynamic organization that consistently allows its users to get paid by sharing their Wi-Fi.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• FlexDesk — FlexDesk is creating a new evolution of the flexible workspace model. Remote workers use the platform to discover and book a dedicated desk or private office by the day. FlexDesk unlocks this inventory by partnering with office landlords and coworking operators that have furnished, underutilized space.
• SearchEye — Get tech-driven SEO at scale, speed and a fraction of the cost compared to traditional agencies. Acquire PR Mentions, Digital PR and Content.
• Volition — Volition is the largest marketplace of industrial components, built just for hardware teams. We make it easy to find and purchase off-the-shelf parts.

Portfolio highlights

• Ello — Ello is an app-based reading coach that listens to your child read from real books, teaches and motivates them, and transforms them into enthusiastic readers.
• Brine.fi — The best onchain spot trading crypto exchange
• Automat AI — Robotic process automation for Chrome using GPT3 guided Computer Vision

Portfolio highlights

• MetaFi — MetaFi operates as a Trading Metaverse. Trading Metaverse is a new kind of social trading experience governed by its users.
• Obscuro Labs — Obscuro is a layer 2 solution for Ethereum that brings privacy. It ensures the inputs, ledger state and execution are always encrypted. No changes to Dapps, just migrate and gain privacy.
• Thetanuts Finance — Thetanuts is a multi chain structured products protocol with automated strategies to generate income

Portfolio highlights

• zkLink — zkLink is a unified middleware layer connecting L1 chains and L2 networks with zk-SNARKs technology, reshaping the crypto landscape for DeFi, NFT, and RWA trading.
• Optix — Optix is ​​a multi-chain option protocol service provider.
• Blocklords — Be part of the most ambitious strategy game of our age.

Portfolio highlights

• Airstack — Every day there are millions of blockchain transactions. Airstack makes sense of them.
• Jumbo — Jumbo is the solution for a decentralized solution that is ungoverned that seeks to lower the entry point to trade. They develop, tune, and process inherently present on the near blockchain. Their interface is used to configure a set of parameters for the asset. They provide a set of functionalities and interface-embedded constituents that help todetect the pools.
• Liqwid Labs — Liqwid Labs is an on-chain lending protocol on Cardano.

Portfolio highlights

• MixMob — A P2E Game on Remix Culture. grab your mask and start your journey - level up from card strategy battle game to full MMO glory!
• Parcel — Parcel is on a mission to empower people with the tools they need to find their home in the metaverse. Born out of an industry that was scattered and lacked transparency, Parcel developed the first comprehensive marketplace tailored exclusively for virtual real estate. By aggregating digital land listings and fostering connection between landownersand creators, Parcel offers the full suite of services needed to build a thriving metaverse community and economy.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Dmail — Dmail Network is a decentralized mailbox that provides a safe and private environment for users' communication, storage, tokens, and NFTs. The company was founded by Mittal S. and Lucas L. in 2021.
• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• IQ Labs — IQ Marketplace offers unique NFTs with exclusive utilities, boosting your in-game experience. With flexible renting parameters and multiple payment options, rent without collateral and unlock the full utility of NFTs. Say goodbye to gas fees with our gasless renting feature and multiply the value of NFT collections with our multi-utility renting. Explore now