Top 50 Health Care Angel Investors in Japan (May 2026)

Portfolio highlights

• M-Box — M-Box provides IT solutions to the pharmaceutical and healthcare industries and operates web services.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Willbox — Willbox is an international logistics company providing an international logistics digital platform for shippers and logistics companies. The company's platform "Giho" connects shippers and logistics companies (transportation, packaging, warehousing, customs clearance, etc.) with a direct contract. It visualizes the three elements of[lead time, money, and safety], which have been regarded as a black box, and supports comparative examination and decision making. Willbox digitizes the packing technique of wooden boxes and steel, mandatory for international logistics, and incorporated them into their system. Their mission is to solve the logistics issues focusing on the large cargo of industrial products.The company was founded in 2019 and is based in Yokohama-shi, Kanagawa.

Portfolio highlights

• AceRNA — AceRNA contributes to regenerative medicine and drug discovery through the discovery of novel miRNA functions. It began operation in April 2018, with its headquarters in Kyoto in Japan.
• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Go Visions — Go Visions engages in the edutainment tech for children and human resources services.

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• Epistra — Epistra accelerates research and development in life sciences.
• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.

Portfolio highlights

• Onepair — Onepair is a job consulting and recruiting company. Onepair is to co-creating careers by talking about real-world ace with active ace.
• Strainer Co., Ltd. — Strainer Co., Ltd. is an information distribution platform that conveys corporate information centered on financial data. Although there are not a few media to deliver financial information, the company's strengths are strong to be easily viewed, including financial information of overseas companies.
• LAMILA — LAMILA develops system that improves the creation of retail stores.

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• RE — RE specializes in smartphone application design and development.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Plott — Plott producing youtube animation platform under Vision “Become a Content holder from YouTube”. In August 2019, the company name was changed from Fabo to Plott. Plott, the new company name, is derived from the plot that you make before writing novels, etc., and the idea that “I want to make content all the time” is put in the company name.
• Now Do — Now Do provides online growth revolution platform.
• FiNANCiE — FiNANCiE is a social networking service.

Portfolio highlights

• DOFA — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Best Beer Japan — Best Beer Japan provides a barrel tracking software for craft beer and barrel sharing. The company was founded in 2018.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• vivid garden — vivid garden is an Agriculture company.
• SAMURAI Security —

Portfolio highlights

• JAPAN HEALTHCARE — Japan Healthcare is a healthcare start-up that works on the prevention of musculoskeletal diseases with environmentally-friendly preventive medicine . Japan Healthcare Build a preventive system for musculoskeletal diseases with environmentally-improving preventive medicine.
• Japan Healthcare Info — Japan Healthcase Info locates english-speaking doctors for you and makes appointments
• Legal Technology Japan — Legal Technology is into development of cloud-based research tool called 'Legal Library' using legal books.

Portfolio highlights

• Revorf — Revorf analyzes data and develops AI-related to infectious diseases and healthcare.
• abillion — Find tips for plant-based food & products near you. Join the community to share reviews of restaurants & brands. Raise funds & drive sustainability!
• RIMM Sustainability — RIMM Sustainability provides a SaaS platform that enables companies of all sizes to optimise their sustainability management effort. It builds tools for sustainability management, reporting and optimisation.

Portfolio highlights

• CUICIN — Quickin is changing the travel experience with the digital transformation.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Magic Shields — Magic Shields is a manufacturer and seller of floors, nursing care, and welfare products.

Portfolio highlights

• Cocoach — Cocoach provides online education service.
• Data Viz Lab — Data Viz Lab is a platform that offers data analysis, visualization consulting, and data human resource development support.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC Japan — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Regain — Regain provides remote on-demand physical rehabilitation treatment solutions and video tutorials through the internet. It was launched by Hiroki Watanabe.
• ENDROLL — ENDROLL is a startup that develops and provides entertainment content using XR. Company Profile
• Autify — Autify - Revolutionizing Software Testing with the most advanced AI-powered Software Testing Tool

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• Morght — Morght is an information technology service company.
• MiL Inc — Emerging products for healthcare food brands Producing food retailing and wholesale recipe development Restaurant management Catering media operation.

Portfolio highlights

• Elaly — Elaly Technology makes life better for people around the world.We aim to make the value of money and the experience gained from it flatter.As many people as possible will use technology to realize a happier life, independent of the money economy.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!
• DariaMe — DariaMe is a web media planning, development and operation, planning and production of various contents, online consultation service.

Portfolio highlights

• Penmark —
• NoSchool — NoSchool is possible to ask a study teacher to a professional teacher who is working as a tutor or a private lecturer for free.
• Posiwill — Posiwill is a operating a career consultation service with job seekers billing type.

Portfolio highlights

• Morght — Morght is an information technology service company.
• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.
• Dots for — Dots for is a technology that aims to improve the lives of rural residents by providing them with digital services.

Portfolio highlights

• AirX — AirX is a management service company specializing in air transportation agency business and travel arrangement business. The company leverages technology to transform the notion of mobility into an unprecedented experience. It also provides services such as CodeShare, AIROS Skyview, and AIROS Air Loss. AirX will create the movement of the futuresociety, sightseeing and the way of life of helicopter, Empty MaaS, Flying taxi, eVTOL, and Next-generation traffic.AirX was established on February 23, 2015, and is based in Shinjuku-ku, Tokyo, Japan.
• yup — yup is providing services to support freelance people's funding.The freelance population in Japan has been shown to continue to increase in many Chosa. While working styles are diversified, they are not able to respond to the development of the working environment, and they will develop their business to change the situation where problemssuch as funding, credit, sexual harassment, and power harassment are accumulated.
• Meetscare — Meetscare provides correct information and supports the self-awareness of all people involved in care. The company provides a wealth of information to ensure optimal care and create a mechanism for the realization. Users can make a telephone consultation and web diagnosis and search for free information using the system.Meetscare was founded on2016 and is headquartered in Arakawa, Tokyo.

Portfolio highlights

• emol — emol is an application that records emotions and talks with AI robots.emol provide personalized mental and productivity training based on mental data to promote employee well-being and increase employee engagement.

Portfolio highlights

• Adskom — ADSKOM is an Advertising Technology company with dedicated mission to empower digital advertising industry with programmatic advertising platforms and insightful business services. With technology & business team in Indonesia, Singapore & USA we strive to deliver effective digital advertising solution for you
• MEDCARE — Medcare is a medical service corporation.
• WASEDA M&A PARTNERS — APAC Startup-focused M&A and Financial Consulting Firm (Founders are all graduates of Waseda Business School, Waseda University)

Portfolio highlights

• Pixta — Pixta company’s goal is to assist graphic professionals in the transfer, tracking and collaboration of digital media over the Internet. We build Internet “Cloud”-based applications that provide a great customer experience, easy-to-use, secure and reliable.To assist our customers in transferring large-files simply and securely across the Internet,we built PixtaSynapse. Using PixtaSynapse, the sender needs only a web-browser to send files. To make the service super-reliable, we built the servers and core-technology for our custom file processing pipeline. We then located those key-servers one-hop off the Internet backbone to reduce latency. Our core file pipeline is physically located in a secure Class A co-location facility. We have setup secure, automated, off-site backups to safeguard our customers data in case of a catastrophic emergency.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Address Japan — ADDress is a provider of co-living spaces in both urban and rural areas, enabling people to live in a range of luxurious residences at fixed prices.

Portfolio highlights

• Quatre — Quatre is a planning, operation and sales of all real promotion platform air catalog.
• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• MiL Inc — Emerging products for healthcare food brands Producing food retailing and wholesale recipe development Restaurant management Catering media operation.

Portfolio highlights

• Gracia Japan — Gracia is an EC business and media business that provides coloring precious moments and enriching human connections.
• Syukatsu Labo — Syukatsu Labo is a leading company that solves various problems in an aging society.
• Somewhere — Somewhere is engaged in the travel and transportation business.

Portfolio highlights

• Cosic — KAREN, operated by ASHBERY, provides 3D interior coordination services according to personal preferences and lifestyle. Features of the service are the simplicity of use and the high quality of KAREN output. This is because users only have to upload photos of their rooms and pick three of their favorite interior photos on KAREN, and they arecommitted to securing the interior coordinator.The company was founded in 2018 and is based in Japan.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!

Portfolio highlights

• DOFA — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Alliance Cloud — Alliance Cloud primarily engages in the Sales Tech and BtoB Sales Outsourcing Business.
• Cloud Franchise — Cloud Franchise is a cloud kitchen model that aims to maximize the kitchen occupancy rate of restaurants.

Portfolio highlights

• 3Sunny — 3Sunny is a company which helps in solve medical care issues so that everyone can feel at ease. The company solves the problems of people in the field while utilizing technology, and create a reliable society that will eventually reach the desired end. 3Sunny was founded in July 2016 and is headquartered in Tokyo, Japan.
• Contrea — Contrea develops and operates a tool that helps doctors explain the patient to be convinced and treated.

Portfolio highlights

• Clear — Clear, Inc. operates sake subscription service “SAKELIFE".
• Cub McPaws — Buy comfortably fashionable kids clothes (4 - 12 years) online in India from Cub Mcpaws at best prices. Gorgeous dresses, jumpsuits, t-shirts, shirts & bottom wear for boys and girls | Free Shipping | COD
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.

Portfolio highlights

• HOMMA — Inspired Modern Living. Homes to elevate healthy urban lifestyles. Design. Build. Technology.
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.
• CAREER BIJIN — Career bijin is a total support company.

Portfolio highlights

• emol — emol is an application that records emotions and talks with AI robots.emol provide personalized mental and productivity training based on mental data to promote employee well-being and increase employee engagement.
• BoostIO — MAISIN&CO makes meetings efficient. MAISIN&CO was founded in 2014.

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• Manabie — Manabie is an Education Technology start-up company on a mission to provide a new style of online & offline merged learning around the world. We provide students with everything they need for efficient learning; high-quality learning materials, great learning environments, personal coaches and more! We believe that our new method of learning,integrating online and offline will dramatically innovate the way students learn.
• Luup — Luup is an Internet Company.

Portfolio highlights

• Villio — Villio provides talent experience SaaS which helps companies with human resource development and recruitment of talented engineers.
• HarvestX — HarvestX manufactures fully automatic robots which contributes to the shortage of agricultural human resources and stable food production
• SPeak Corporation — SPeak Corporation operates JPort Match that is involved in direct recruiting service. It is a global career platform for budding new talents.

Portfolio highlights

• Plus-medi — Plus Medi is the developer of MyHospital, a medical care and management app offering personal health record (PHR) solutions.The app aims to help users by reducing the time they spend at the hospital or doctor's office. MyHospital also includes features like bills payment, medication management, and online paperwork.

Portfolio highlights

• BeatFit — BeatFit is a fitness-tech startup based in Japan.
• PROGRIT — PROGRIT is an English-related media management company.
• Luup — Luup is an Internet Company.

Portfolio highlights

• RIZAP — RIZAP is a chain of a private gym that offers fitness training and consulting services.
• Jupiter Intelligence — The Trusted Leader in Climate Risk Analytics. Learn about our best-in-science solutions.

Portfolio highlights

• Helpfeel — Our vision is to make saving, sharing, and exploring ideas as natural as breathing. On this journey we're humbled to be helping millions around the world from solo makers to university research labs, from gamers to pro designers, and large to small teams like ours.
• HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.

Portfolio highlights

• Zeigo — Zeigo is a company formed by a team of like-minded clean energy & tech pioneers with a mission to help companies transition to a low carbon economy.
• Ecolectro — Ecolectro is solving the biggest challenges in making Green Hydrogen. Our alkaline ion-exchange membranes and polymers make clean fuel and decarbonize industry.
• Sniffer Robotics — Comprehensive methane emissions detection and quantification, advanced imagery and analytics; Sniffer Robotics provides advanced solutions that benefit the environment.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• Now Do — Now Do provides online growth revolution platform.
• SAURUS JAPAN —

Portfolio highlights

• Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
• matsuri technologies — matsuri technologies is a real estate tech company that provides solutions to support private property rentals. The company's products include m2m Systems, an Airbnb management platform that helps business operators to manage their accounts, communicate with guests, automate check-ins, offer customer service, and more.

Portfolio highlights

• LIFT99 — LIFT99 is a coworking hub and network of startup founders in Tallinn, Estonia, and Kyiv, Ukraine. In 2018, we launched our Skillsharing Platform for founders around the world.
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.
• AnotherBall — AnotherBall = Digital + Entertainment + Token economy

Portfolio highlights

• Elaly — Elaly Technology makes life better for people around the world.We aim to make the value of money and the experience gained from it flatter.As many people as possible will use technology to realize a happier life, independent of the money economy.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!

Portfolio highlights

• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.

Portfolio highlights

• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
• Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
• MinD in a Device — MinD in a Device Co., Ltd. is a university-launched venture that aims to port human consciousness to devices (machines and computers) in the medium to long term based on long-term research results on consciousness. As the first step toward realization, we will evolve and deepen the "generation model" considered to be the source ofconsciousness, and promote the development of next-generation AI and social implementation.

Portfolio highlights

• Sagri — Sagri is developing agriculture software for experienced farmers.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!
• Syukatsu Labo — Syukatsu Labo is a leading company that solves various problems in an aging society.

Portfolio highlights

• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• FamiOne — FamiOne is creating a society that will support the future of couples who want to receive children.
• Petokoto — Petokoto is a media created with pet specialists such as certified veterinarians.
• Reiwa Travel — Reiwa Trave is a digital travel agency intended that optimizes overseas travel. The company's platform uses online travel booking tools that provide digitalized contracts along with trip management, thereby enabling its customers' vacation and leisure experiences.

Portfolio highlights

• Taliki — Taliki is a Coworking Space Operates Social Entrepreneurs Development Support for Intrepreneur Development.
• ONE NOVA — One Nova (ワンノバ) is a lifestyle brand and online platform that offers a range of innerwear products, such as men's boxers.
• vivid garden — vivid garden is an Agriculture company.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.

Portfolio highlights

• MedPeer — MedPeer operates as a community site for doctors. MedPeer is a recruitment agency collective registration service.MedPeer operation of "MedPeer," a collective intelligence service/ community website for physicians.