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Top 10 Biotechnology VC Funds & Investors in South Africa (May 2026)

The most active venture capital funds investing in South Africa Biotechnology startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Biotechnology startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Cult Food Science
VC Fund
2 United States, South Africa, Canada Seed, Pre-Seed Food and Beverage, Biotechnology, Food Processing $275k–$12M
Futuregrowth Asset Management
VC Fund
2 South Africa, France, United States Seed, Series B Software, Financial Services, Medical Device $4M–$5.3M
E4EAfrica
VC Fund
1 South Africa, France, The Netherlands Seed, Series A, Series B Internet, Logistics, E-Commerce $1M–$5.3M
Sustainable Food Ventures
VC Fund
1 United States, India, Germany Pre-Seed, Seed, Angel Food and Beverage, Biotechnology, Food Processing $100k–$4M
Alethea Capital Management
VC Fund
1 United States, South Africa Series A, Series B, Series C Biotechnology, Health Care, Medical $2.5M–$10M
HAVAÍC
VC Fund
1 South Africa, United States, Kenya Seed, Pre-Seed Health Care, Financial Services, Software $54k–$4M
Twynam Agricultural Group
VC Fund
1 United States, Australia, Singapore Series A, Seed Agriculture, Food Processing, Seafood $1.9M–$33M
Ministry of programming
VC Fund
1 South Africa Pre-Seed Biotechnology
Kale United
VC Fund
1 United Kingdom, Sweden, India Seed, Pre-Seed Food and Beverage, Food Processing, Biotechnology $100k–$1.4M
Anonymous Trust
VC Fund
1 United States, South Africa, United Kingdom Pre-Seed, Series A, Seed Software, Computer, Market Research
Access all 17 VC funds in South Africa Biotechnology startups.

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Investor list

Cult Food Science
VC Fund · 2 investments in South Africa Biotechnology startups

CULT Food Science is an investment company focused on supporting and advancing the technology behind the future of food.

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Investment focus

  • Industry: Food and Beverage, Biotechnology, Food Processing
  • Stage:Seed, Pre-Seed
  • Geography: United States, South Africa, Canada

Investor stats

  • Total investments: 23
  • Round size: Seed $300k–$12M; Pre-Seed $275k–$2.4M
  • Lead/follow: 52% lead, 48% follow

Portfolio highlights

  • Novel Farms — Novel Farms uses microbial fermentation to develop cruelty-free, inexpensive and tunable bioscaffolds for the production of cell-based meat products. Novel Farms mission is to craft the taste and texture of the gourmet meats and transform cell-based meat consumption into a sought-after culinary experience for the next generation of consciouseaters.
  • Minus — A sustainable coffee alternative, combining the taste, look, and smell of coffee with a smaller footprint to ensure a brighter future for coffee and the planet.
  • Unicorn Biotechnologies — Unicorn Biotechnologies is developing a fully automated manufacturing platform to enable cellular agriculture producers to seamlessly scale products from the lab bench to supermarket shelves. Our full stack platform combines hardware, software and analytics to completely automate cellular agriculture manufacturing, reducing costs and increasingproduct quality. By providing a clear path to scale cellular agriculture from grams to tons, we will improve human and planetary health and drive the transition to animal free agriculture.
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Futuregrowth Asset Management
VC Fund · 2 investments in South Africa Biotechnology startups

Futuregrowth manages the full range of fixed interest and developmental impact funds on behalf of our clients. We are committed to managing and investing our clients' funds in a responsible manner.

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Investment focus

  • Industry: Software, Financial Services, Medical Device
  • Stage:Seed, Series B
  • Geography: South Africa, France, United States

Investor stats

  • Total investments: 10
  • Round size: Seed $4M–$5.3M
  • Lead/follow: 70% lead, 30% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Inseco — Inseco is an IT company that specializes in management solutions, ERP, CRM, GED, HR, and business solutions.
  • SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
  • Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.
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E4EAfrica
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Biotechnology startups

E4E (“Entrepreneurs for Entrepreneurs”) specializes in supporting early stage ventures in South Africa from very early stage (pre-series A) to scale up.E4E focus on smart entrepreneurs and business ideas that are great businesses and make a significant contribution to a better (South) Africa.

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Investment focus

  • Industry: Internet, Logistics, E-Commerce
  • Stage:Seed, Series A, Series B
  • Geography: South Africa, France, The Netherlands

Investor stats

  • Total investments: 11
  • Round size: Seed $3M–$5.3M; Series A $1M–$4.3M
  • Lead/follow: 45% lead, 55% follow

Portfolio highlights

  • Talk360 — Talk360 is an easy-to-use calling app that helps people make affordable international calls to any mobile and landline number. They believe that reliable communication and digital services must be affordable and accessible to everyone, regardless of someone's background. Especially people in emerging countries in Africa, who often need theseservices the most, do not always have the necessary banking possibilities. To bridge this distance, Talk360 will launch the world's first single checkout platform for Africa. This platform will combine all locally available payment methods and currencies across Africa, together with over 1.25 million cash points of sales, and will eventually be available to other companies as well. This means that 500 million Africans will be able to purchase digital services they never had access to before.
  • SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
  • Yebo Fresh — Powering South Africa's Township Economy.
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Sustainable Food Ventures
VC Fund · Raleigh, North Carolina, United States · 1 investments in South Africa Biotechnology startups

SFV backs globally early-stage founders building leading Future of Food companies that are: #Cell-based #Plant-based #Recombinant

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Investment focus

  • Industry: Food and Beverage, Biotechnology, Food Processing
  • Stage:Pre-Seed, Seed, Angel
  • Geography: United States, India, Germany

Investor stats

  • Total investments: 32
  • Round size: Seed $845k–$4M; Pre-Seed $100k–$2.1M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • Farmless — A farmless fermentation platform has the potential to create an entirely new food repertoire, producing proteins, carbohydrates, beneficial fats, vitamins, and minerals from the ground up," explained Oner. "We are creating a new interface between food and electricity by domesticating microbes chosen for their food properties and abilityto grow on renewable energy-based feedstocks.
  • Daisy Lab — Daisy Lab pioneers precision fermentation technology in New Zealand
  • Atlantic Fish Co — Developing sustainable, cultivated seafood using cellular agriculture
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Alethea Capital Management
VC Fund · Rancho Santa Fe, California, United States · 1 investments in South Africa Biotechnology startups

Alethea Capital Management is an SEC-registered investment advisor founded in March of 2011. As an investment management and research firm, the mission of Alethea is simple – to provide the highest level of service and guidance to our clients with honesty, integrity, and transparency. The firm’s services include fee-based asset management,research/advanced quantitative systematization, manager/strategy evaluation, and comprehensive planning. Alethea’s center of operations is in San Diego, CA.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, South Africa

Investor stats

  • Total investments: 5
  • Round size: Series A $2.5M–$10M
  • Lead/follow: 20% lead, 80% follow

Portfolio highlights

  • 3X4Genetics — The future of healthcare is personalized. Build a more successful practice and transform more lives using the power of DNA-driven health recommendations, through DNA & Genetic Testing!
  • Lipidio Pharmaceuticals — Lipidio Pharmaceuticals is a healthcare company that focuses on advancing a molecule to treat diseases associated with excess body fat. It includes non-alcoholic steatohepatitis, Prader-Willi syndrome, and antipsychotic drug-induced weight gain. The company was founded in 2018 and headquartered in San Diego, California.
  • SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.
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HAVAÍC
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Biotechnology startups

HAVAÍC is an investment and advisory firm that specialises in early-stage, high-growth African businesses with proven concepts and global prospects, offering investment opportunities to sophisticated investors and international venture capital companies with an interest in Africa. As a complementary offering, HAVAÍC provides corporate advisory andcapital raising services to emerging, internationally scalable businesses.

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Investment focus

  • Industry: Health Care, Financial Services, Software
  • Stage:Seed, Pre-Seed
  • Geography: South Africa, United States, Kenya

Investor stats

  • Total investments: 22
  • Round size: Seed $54k–$4M
  • Lead/follow: 73% lead, 27% follow
  • Last fund: May invest from a new fund soon — last raise in 2021

Portfolio highlights

  • Talk360 — Talk360 is an easy-to-use calling app that helps people make affordable international calls to any mobile and landline number. They believe that reliable communication and digital services must be affordable and accessible to everyone, regardless of someone's background. Especially people in emerging countries in Africa, who often need theseservices the most, do not always have the necessary banking possibilities. To bridge this distance, Talk360 will launch the world's first single checkout platform for Africa. This platform will combine all locally available payment methods and currencies across Africa, together with over 1.25 million cash points of sales, and will eventually be available to other companies as well. This means that 500 million Africans will be able to purchase digital services they never had access to before.
  • FinAccess — FinAccess is a banking software for microfinance organisations.
  • Right Now Response — Your go-to for expert breakdown assistance. Our dedicated team ensures you're back on the road swiftly and safely. Contact us for reliable support today!
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Twynam Agricultural Group
VC Fund · Sydney, New South Wales, Australia · 1 investments in South Africa Biotechnology startups

Twynam Group is a leading Australian Funds Manager investing in early-stage climate tech. We also operate an agricultural and property portfolio.

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Investment focus

  • Industry: Agriculture, Food Processing, Seafood
  • Stage:Series A, Seed
  • Geography: United States, Australia, Singapore

Investor stats

  • Total investments: 12
  • Round size: Seed $1.9M–$3.6M; Series A $3.4M–$33M
  • Lead/follow: 17% lead, 83% follow

Portfolio highlights

  • Voltpost — The lamppost electric vehicle charger.
  • Earthodic — Earthodic is an Australian materials science company creating functional biobased coatings. Paperbarc by Earthodic is a biobased water-resistant coating for pulped or paper products. It has better water-resistance than wax coatings, more sustainable and circular than plastic coatings. Repulpable. Re
  • Ocean Rainforest — Ocean Rainforest offer a collection of premium fully-traceable seaweed products, mostly for food and cosmetic producers.
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Ministry of programming
VC Fund · Sarajevo, Federation of Bosnia and Herzegovina, Bosnia and Herzegovina · 1 investments in South Africa Biotechnology startups

We build startup software companies from the first line of code partnering with interesting founders and enterpreneurs.We believe we have the know-how to bootstrap early-stage products and scale them into successful products. We have a nice portfolio of exciting startups in Fintech, Healthcare, E-commerce domains, and we are building more everyday.

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: 100% lead, 0% follow

Portfolio highlights

  • BioCertica — BioCertica combines advanced genomics technology to interpret your DNA and provide recommendations to unlock a healthy lifestyle.
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Kale United
VC Fund · Stockholm, Stockholms Lan, Sweden · 1 investments in South Africa Biotechnology startups

Kale United offers a portfolio of over 75+ plant-based game changers

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Investment focus

  • Industry: Food and Beverage, Food Processing, Biotechnology
  • Stage:Seed, Pre-Seed
  • Geography: United Kingdom, Sweden, India

Investor stats

  • Total investments: 20
  • Round size: Seed $330k–$1.4M; Pre-Seed $100k–$945k
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • Loki Foods — We're producing sustainable, plant-based foods from the Arctic. Iceland’s first plant-based cod and seafood!
  • THE PACK — Nutritionally complete vegan dog food. Grain-free & developed with food scientists & animal nutritionists, try our delicious vegan dog food now.
  • Swedish Temptations — Swedish Temptations, founded in 2019 by CEO Pia Qvarnström, built a brand named Bärta for producing organic, vegan and fermented food. The ingredients include Swedish split peas.
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Anonymous Trust
VC Fund · San Francisco, California, United States · 1 investments in South Africa Biotechnology startups

Trust

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Investment focus

  • Industry: Software, Computer, Market Research
  • Stage:Pre-Seed, Series A, Seed
  • Geography: United States, South Africa, United Kingdom

Investor stats

  • Total investments: 8
  • Lead/follow: no public data

Portfolio highlights

  • The Index — The Index is a platform of cutting-edge technology used by clients in the fashion and retail industry to grow their companies and enhance their digital footprints
  • De Novo Foodlabs — De Novo FoodlabsThe future of nutrients
  • Smart Separations — Smart Separations is a limited company based in London UK that has patented an innovative microfiltration technology to produce ceramic filters with self-assembled controllable pores of uniform size in the range between <1 and 50µm. This tight pore size control and range availability will revolutionise the field of MF with a cost-effectiveproduct.It aims to be the world’s leader in MF and particle separations technology – filling the void gap that exists in the market nowadays.
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Biotechnology VC funding in South Africa at a glance

Stats across 13 deals from 17 investors.

17
investors
in South Africa Biotechnology startups
13
deals
in South Africa Biotechnology startups
$550k
median round
in South Africa Biotechnology startups
59%
lead investors
lead at least one round
31%
Pre-Seed
most common funding stage

Access all 17 VC funds in South Africa Biotechnology startups.

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