# Top 50 Manufacturing Startup Investors in United States in May 2026

## Innova Memphis
- Type: VC Fund
- Location: Memphis, Tennessee, United States
- Relevant deals: 28
- Stages: Seed, Pre-Seed, Convertible Note
- Focus: Health Care, Medical, Medical Device

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

## Lux Capital
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 24
- Stages: Series A, Seed, Series B
- Focus: Software, Health Care, Biotechnology

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

## Houston Angel Network
- Type: VC Fund
- Location: Houston, Texas, United States
- Relevant deals: 22
- Stages: Seed, Series A
- Focus: Health Care, Software, Information Technology

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

## Khosla Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 22
- Stages: Series A, Series B, Seed
- Focus: Software, Health Care, Artificial Intelligence

Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.

## Founders Fund
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 20
- Stages: Series A, Seed, Series B
- Focus: Software, Health Care, Internet

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

## Clean Energy Ventures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 19
- Stages: Series A, Seed, Convertible Note
- Focus: Energy, Manufacturing, Renewable Energy

Clean Energy Ventures invests in scalable early-stage climate tech startups and clean energy technologies addressing global climate change.

## Alumni Ventures
- Type: VC Fund
- Location: Manchester, New Hampshire, United States
- Relevant deals: 19
- Stages: Seed, Series A, Series B
- Focus: Software, Information Technology, Health Care

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

## Toyota Ventures
- Type: VC Fund
- Location: Los Altos, California, United States
- Relevant deals: 18
- Stages: Series A, Seed, Series B
- Focus: Artificial Intelligence, Software, Robotics

Toyota Ventures is a San Francisco Bay Area-based venture capital firm that invests in early-stage startups from around the world. Founded in July 2017, its mission is to discover what’s next for Toyota by helping startups bring disruptive technologies and business models to market quickly. With more than $500 million in assets under management,the firm’s funds include the Toyota Ventures Frontier Fund focused on artificial intelligence, cloud computing, autonomy, mobility, robotics, smart cities, digital health, financial technologies, materials, and energy; and the Toyota Ventures Climate Fund focused on innovative solutions for carbon neutrality.

## Asymmetry Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 18
- Stages: Seed, Pre-Seed, Series A
- Focus: Software, Health Care, Biotechnology

Asymmetry Ventures invests in scalable early-stage companies with exceptional defensibility.

## Fifty Years
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 18
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

WE BACK HEROES   using technology to solve the world's biggest problems

## Flybridge
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 18
- Stages: Seed, Series A, Series B
- Focus: Software, Information Technology, SaaS

Flybridge is a Seed-stage venture capital firm based in Boston and New York City. We are excited to invest in companies and entrepreneurs who share our vision for the power of community across a range of sectors.

## Prelude Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 17
- Stages: Series A, Series B, Series C
- Focus: Software, Energy, Manufacturing

Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. For us, climate is everything.

## New Enterprise Associates
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 17
- Stages: Series B, Series A, Series C
- Focus: Software, Health Care, Biotechnology

New Enterprise Associates, Inc. is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors, and geographies. With over $19 billion in cumulative committed capital since the firm’s founding in 1977, NEA invests in technology and healthcare companies at all stages in a company’slifecycle, from the seed stage through IPO. The firm's long track record of successful investing includes more than 210 portfolio company IPOs and more than 360 acquisitions.

## Intel Capital
- Type: VC Fund
- Location: Santa Clara, California, United States
- Relevant deals: 17
- Stages: Series B, Series A, Series C
- Focus: Software, Information Technology, Enterprise Software

Intel Capital is uniquely positioned to help build the companies of tomorrow. Our investment team is backed with deep domain knowledge and the resources of Intel to assist companies in their paths to success.

## Right Side Capital Management
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 16
- Stages: Seed, Pre-Seed, Convertible Note
- Focus: Software, SaaS, Health Care

Right Side Capital Management is a venture capital firm that helps startups build their company. It invests exclusively in the pre-seed round of technology startups and makes 75-100 investment per year. The firms prefers to invest in diversified technology sectors such as the internet and cloud companies.RSCM was established in 2010 and is basedin San Francisco, California.

## MB Venture Partners
- Type: VC Fund
- Location: Memphis, Tennessee, United States
- Relevant deals: 16
- Stages: Seed, Series B, Series C
- Focus: Health Care, Medical, Medical Device

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

## Congruent Ventures
- Type: VC Fund
- Location: Oakland, California, United States
- Relevant deals: 16
- Stages: Series A, Seed, Series B
- Focus: Software, Energy, Renewable Energy

Congruent Ventures is a venture capital firm that seeks to invest in Mobility and Urbanization, Energy Transition, Food and Agriculture, and Sustainable Production & Consumption sectors. We look for technology companies that will positively impact our energy and resource consumption. If we see an opportunity to partner with a like-minded teamfocused on scale across hardware, software, or services, we’re interested.

## Maine Angels
- Type: VC Fund
- Location: Portland, Maine, United States
- Relevant deals: 16
- Stages: Seed, Series A
- Focus: Health Care, Software, Biotechnology

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

## Eclipse Ventures
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 16
- Stages: Series A, Series B, Seed
- Focus: Software, Robotics, Artificial Intelligence

Palo Alto based Eclipse Ventures partners with entrepreneurs boldly transforming the essential industries that define and propel economies. Learn more.

## Root Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 16
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Machine Learning

Root Ventures is a seed-stage venture capital firm that invests in technical teams working on deep tech. The firm specializes in the fields of financial services, venture capital, and investments.
It was founded in 2013 and headquartered in San Francisco, California.

## Creative Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 15
- Stages: Seed, Series A
- Focus: Software, Health Care, Artificial Intelligence

Creative Ventures is a deep tech venture firm investing in early-stage companies solving humanity’s most critical crises. Led by a team of world-class experts, our deep tech acumen is informed by rigorous research, unmatched market understanding, and the dedication to lead our companies to success.Today’s problems can’t be solved by yesterday’ssolutions. Let’s get Creative.

## Kleiner Perkins
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 15
- Stages: Series B, Series A, Series C
- Focus: Software, Health Care, Information Technology

Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley.

## Breakthrough Energy Ventures
- Type: VC Fund
- Location: Paris, Ile-de-France, France
- Relevant deals: 15
- Stages: Series A, Series B
- Focus: Energy, Renewable Energy, Manufacturing

Focused on developing and deploying the critical climate solutions our world needs to reach net-zero emissions by 2050.

## The Engine
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 15
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Manufacturing

A home for Tough Tech founders.

## Ben Franklin Technology Partners of Northeastern Pennsylvania
- Type: VC Fund
- Location: Bethlehem, Pennsylvania, United States
- Relevant deals: 14
- Stages: Grant, Seed, Debt Financing
- Focus: Manufacturing, Health Care, Software

Ben Franklin helps early-stage technology companies and established manufacturers translate innovation into commercial success and economic prosperity.

## Draper Associates
- Type: VC Fund
- Location: San Mateo, California, United States
- Relevant deals: 14
- Stages: Seed, Series A, Series B
- Focus: Software, FinTech, Information Technology

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

## Threshold
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 14
- Stages: Series B, Series A, Series C
- Focus: Software, Internet, Mobile

Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs building innovative consumer, enterprise, and healthcare technology companies.
Threshold was founded in 2019 and is based in Menlo Park, California.

## DCVC
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 14
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Health Care

We are deep tech venture capital.

## Social Capital
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 14
- Stages: Seed, Series A, Series B
- Focus: Software, FinTech, SaaS

At Social Capital, we make big bets on transformational ideas, technology, and people.

## Alliance of Angels
- Type: VC Fund
- Location: Seattle, Washington, United States
- Relevant deals: 13
- Stages: Seed, Series A
- Focus: Software, Health Care, Mobile

Largest and most active angel group in the Pacific Northwest

## Advantage Capital
- Type: VC Fund
- Location: New Orleans, Louisiana, United States
- Relevant deals: 13
- Stages: Debt Financing, Series A
- Focus: Manufacturing, Health Care, Software

Advantage Capital has invested over $3.8 billion in more than 800 portfolio companies and projects nationwide since 1992. The firm specializes in growth equity, lending, and mezzanine debt capital investments spanning three distinct but complementary themes, driving local economic development and lasting impact in underserved communities.____________________Growing Small Business // 800+ PORTFOLIO COMPANIES // 34 STATES // 66,000+ JOBS SUPPORTED //
Small businesses and the entrepreneurs who power them are fundamental to the U.S. economy, driving inclusive economic expansion that allows people and communities to thrive.
Advantage Capital offers debt and equity investment opportunities and can provide senior, unitranche and subordinated debt, as well as minority equity financing. The firm invests in companies from a diverse array of industry sectors, including manufacturing, technology and business services, among others. It seeks to make an initial investment between $500K and $10M in companies with $1M+ EBITDA.Financing Affordable Homes // 89 PROJECTS SINCE 2015 // 8,000+ FAMILIES & SENIORS HOUSED // 7 STATES //
Creating stronger communities goes beyond business investment and jobs. Financing housing in these same communities creates even more positive and lasting impacts.Expanding Renewable Energy Solutions // $130M IN CAPITAL DEPLOYED // 65 PROJECTS // 20,000+ HOMES POWERED //
Increased access to renewable energy supports local green jobs and economic development while building the framework for tomorrow's carbon-free America.
____________________Geographic Focus: Advantage Capital is committed to impact nationwide, with current emphasis in the following states: Alabama, Arkansas, Connecticut, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Mexico, Ohio, Pennsylvania, Tennessee, Texas, Utah, Virginia, West Virginia____________________Advantage Capital is headquartered in New Orleans, Louisiana and has offices in the following locations: St. Louis, MO; New York, NY; Austin, TX; Hanover, NH; Washington, D.C.; Napa, CA; Nevada.

## Bolt
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 13
- Stages: Seed, Pre-Seed, Series A
- Focus: Software, Health Care, Internet of Things

Bolt: Investing at the intersection of the digital and physical worlds

## Clean Energy Venture Group
- Type: VC Fund
- Location: Brookline, Massachusetts, United States
- Relevant deals: 13
- Stages: Series A, Seed
- Focus: Energy, Renewable Energy, Manufacturing

CEVG is an angel investor collective that invest in and mentors early-stage cleantech and climatetech startups across North America.

## Sequoia Capital
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 12
- Stages: Series B, Series A, Series C
- Focus: Software, Information Technology, Internet

We help the daring build legendary companies.

## Schematic Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 12
- Stages: Seed, Series A, Pre-Seed
- Focus: Software, Logistics, Artificial Intelligence

Early-stage venture capital fund focused on investments in technology companies within the supply chain, manufacturing and digital industrial sectors

## 180 Degree Capital
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 12
- Stages: Series B, Series A
- Focus: Manufacturing, Biotechnology, Semiconductor

180 Degree Capital Corp. aims to capitalize on turn-around opportunities in micro-cap stocks with a constructive activist approach.

## Lerer Hippeau
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 12
- Stages: Seed, Series A, Series B
- Focus: Software, E-Commerce, Internet

Lerer Hippeau is an early-stage venture capital fund based in New York City. As founders and operators ourselves, we see returns in relationships

## Applied Ventures
- Type: VC Fund
- Location: Santa Clara, California, United States
- Relevant deals: 12
- Stages: Series B, Series A
- Focus: Manufacturing, Semiconductor, Electronics

Applied Ventures, LLC, is the venture capital arm of Applied Materials, Inc., (NASDAQ: AMAT) investing in innovative startups for over a decade.

## Good Growth Capital
- Type: VC Fund
- Location: Charleston, South Carolina, United States
- Relevant deals: 12
- Stages: Seed, Convertible Note, Series A
- Focus: Health Care, Information Technology, Software

Good Growth Capital specializes in finding, cultivating, and assessing complex science and deep-tech start-ups. GGC invests in seed-stage and Series A deals through the General Fund family and in pre-seed and seed-stage companies through the Infinite Corridor Fund, which primarily targets MIT-affiliated and transformative science start-ups. GGC ismajority women- and minority-owned and is uniquely positioned geographically in both the Southeast and New England.

## Elevate Ventures
- Type: VC Fund
- Location: Indianapolis, Indiana, United States
- Relevant deals: 12
- Stages: Seed, Pre-Seed, Grant
- Focus: Software, Health Care, Information Technology

Elevate Ventures nurtures and develops emerging and existing high-potential businesses into high-performing, Indiana-based companies.They accomplish this by providing rigorous business analysis and robust advisory serivces that connect companies with the resources they need to succeed long-term. As a not-for-profit organization, they are ableto offer unbiased, in-depth perspective and recommendations. Emerging, high-potential businessesElevate Ventures seeks out business endeavors that identify a need in the marketplace and are well-positioned to successfully transition from research to product development to market. High-performing, Indiana-based CompaniesThese companies grow local economies and employment throughout Indiana, in addition to attracting and retaining top-level talent for the Hoosier state. Rigorous business analysisComprehensive due diligence is critical to determining the long-term financial viability of these companies. Robust advisory servicesElevate Ventures provides more than just capital, they partner with entrepreneurs, investors and other local and state organizations to ensure the best return on investment. Resources to succeed long-termIn addition to financial resources, Elevate addressees other market barriers, which may include management, business development, talent identification and retention, and specific technology development challenges. They don't just write a check and walk away - they help sustain business success and growth over time. Unbiased, in-depth perspective and recommendationsWith a seasoned staff and a host of proven outside partners, they provide objectivity and insights that are among the best in their profession.

## Wisconsin Investment Partners
- Type: VC Fund
- Location: Madison, Wisconsin, United States
- Relevant deals: 12
- Stages: Seed, Series A
- Focus: Health Care, Biotechnology, Medical

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members.

## Launch NY
- Type: VC Fund
- Location: Buffalo, New York, United States
- Relevant deals: 12
- Stages: Convertible Note, Seed, Series A
- Focus: Health Care, Software, Food and Beverage

Launch NY is a nonprofit venture development organization in Upstate NY. We provide pro bono mentoring and access to risk capital for high-growth startups.

## Texas HALO Fund
- Type: VC Fund
- Location: Houston, Texas, United States
- Relevant deals: 12
- Stages: Seed, Convertible Note, Series A
- Focus: Health Care, Medical Device, Software

Early Stage Venture Investments

## Braemar Energy Ventures
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 12
- Stages: Series B, Series C, Series A
- Focus: Manufacturing, Energy, Renewable Energy

While energy has been a key to global development since the dawn of the electronic age, the beginning of the new century has seen a tremendous surge in the technology advancements, market activity and the strategic importance of energy around the world. While many companies and investors have sought to take advantage of the tremendous opportunitytoday's energy industry presents, the unique market issues, scientific contributions and complex web of interrelationships require a specialized expertise.Braemar Energy Ventures was formed in 2002 to create a venture capital firm with that expertise. Focused exclusively on technology and communications opportunities in the energy sector, Braemar Energy Ventures has both the industry and operating knowledge to select promising young companies, bring them into the larger energy world and guide them to reach their full potential.The firm's four principals have a long history of successful investments, as well as experience financing and operating companies in the energy sector. Together, they have been responsible for investing in almost 40 energy technology companies, including early stage companies which have grown to become some of the most successful in the sector.Braemar Energy Ventures works with management teams who are skilled in their industry but who can benefit from Braemar's assistance with strategic direction and financing issues. Having worked with many early stage companies, the Braemar Energy Ventures principals understand the challenges that many young companies face and provide invaluable counsel to their portfolio companies on longer-term issues, allowing management to focus on daily operations.

## U.S. Venture Partners
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 12
- Stages: Series B, Series C, Series A
- Focus: Software, Health Care, Information Technology

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

## Mark Cuban
- Type: Angel
- Location: Dallas, Texas, United States
- Relevant deals: 12
- Stages: Seed, Series A
- Focus: Software, Blockchain, Artificial Intelligence

Mark Cuban is the founder of Fireside, Chairman and Founding partner of AXS TV, and the Owner of Dallas Mavericks. Prior to that, he was the Co-Founder of Broadcast.com. Mrk attended the Indiana University Bloomington.

## MassVentures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 11
- Stages: Grant, Seed, Series A
- Focus: Software, Health Care, Manufacturing

MassVentures is a venture capital firm focused on fueling the Massachusetts innovation economy by funding early-stage, high-growth Massachusetts startups as they move from concept to commercialization.

## BoxGroup
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 11
- Stages: Seed, Series A, Series B
- Focus: Software, Health Care, Internet

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

## EnerTech Capital
- Type: VC Fund
- Location: Ambler, Pennsylvania, United States
- Relevant deals: 11
- Stages: Series B, Series C
- Focus: Energy, Software, Manufacturing

EnerTech Capital works hand-in-hand with pioneers and innovators daring to change the world. For 25 years EnerTech’s fundamental focus has been investing and partnering with innovative companies driving informational impact across the energy landscape; with a focus on Mobility, Industry 4.0, and Connected Customer. Since its founding in 1996,EnerTech has made 72 investments and has managed over $500 million in capital commitments. EnerTech works with investors and stakeholders from corporates with growing innovation programs to seasoned investors seeking differentiated opportunities for strategic capital deployment or tailored solutions. EnerTech partners with companies across all stages of enterprise value creation from late development and seed through commercialization and growth. While investment activities are predominantly focused in North America, EnerTech partners with teams globally on an opportunistic basis.

## Propel(X)
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 11
- Stages: Seed, Series A, Series B
- Focus: Health Care, Biotechnology, Software

Propel(x) is where investors discover, evaluate and invest in technology startups and venture capital funds.

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