# Top 50 Life Science Startup Investors in United States in May 2026

## ARCH Venture Partners
- Type: VC Fund
- Location: Chicago, Illinois, United States
- Relevant deals: 21
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

## Northpond Ventures
- Type: VC Fund
- Location: Bethesda, Maryland, United States
- Relevant deals: 19
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Life Science

Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow. Our investments are focused on life sciences, technology, and affiliated industries.

## Alexandria Venture Investments
- Type: VC Fund
- Location: Pasadena, California, United States
- Relevant deals: 18
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

## Novartis Venture Fund
- Type: VC Fund
- Location: Basel, Basel-Stadt, Switzerland
- Relevant deals: 14
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Our primary focus is on the development of novel therapeutics and platforms. We balance the therapeutic focus with investments in medical devices, diagnostics or drug delivery systems. In our investments we look for unmet need and clinical impact, novel proprietary science and understanding of mechanism, management and board experience and capitalefficiency in the program.We prefer to have our initial investment at the early stage to build the company and follow with additional investment in pace with the company:tm:s progress. We continue our approach of larger focused investments and anticipate total investments up to USD 30 to 50 mio per company over its life, but it can be as little as 100'000 USD to get started. We will increase our activities to lead or co-lead deals further and remain open to participate in larger syndicates. SectorsNew therapeutics & platformsMedical devices/implantsDiagnostics/biomarkersDrug delivery/biopolymersGeographyUSA/CanadaEuropeSwitzerlandAsia/Pacific

## RA Capital Management
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 12
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

## Fifty Years
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 11
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

WE BACK HEROES   using technology to solve the world's biggest problems

## 8VC
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 11
- Stages: Seed, Series A, Series B
- Focus: Software, Health Care, Information Technology

8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.

## Hatteras Venture Partners
- Type: VC Fund
- Location: Durham, North Carolina, United States
- Relevant deals: 10
- Stages: Series A, Series B
- Focus: Biotechnology, Health Care, Medical

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

## 5AM Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 10
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries.
5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

## OrbiMed
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 10
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

## Atlas Venture
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 10
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

## MPM Capital
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 10
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Powering Breakthroughs in Life Sciences

## Third Rock Ventures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 10
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.

## Alix Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 9
- Stages: Seed, Series A, Pre-Seed
- Focus: Biotechnology, Health Care, Life Science

Supporting early stage Life Science startups driving patient impact. Born from our collective experience as founders, we set out to build the fund we wanted to raise from....

## KdT Ventures
- Type: VC Fund
- Location: Austin, Texas, United States
- Relevant deals: 9
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

KdT Ventures is the standard for early-stage frontier science investing.

## SR One
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 9
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

SR One Capital Management is a leading trans-Atlantic biotech venture capital firm that partners with top entrepreneurs, scientists and investment partners to seek to build elite biotechnology companies. Our mission is to translate ground-breaking technologies into next generation medicines to benef

## Sahsen Ventures
- Type: VC Fund
- Location: Seattle, Washington, United States
- Relevant deals: 9
- Stages: Series A, Seed
- Focus: Biotechnology, Health Care, Non Profit

Sahsen Ventures is a venture capital firm making investments in for-profit and nonprofit organizations with an emphasis on technology and biotechnology. It was established in 2016 and is based in Seattle, Washington.

## Rev1 Ventures
- Type: VC Fund
- Location: Columbus, Ohio, United States
- Relevant deals: 9
- Stages: Seed, Series A
- Focus: Software, Health Care, Information Technology

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

## DCVC
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 9
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Health Care

We are deep tech venture capital.

## Andreessen Horowitz
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 9
- Stages: Series A, Series B, Seed
- Focus: Software, Information Technology, Internet

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

## Versant Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 9
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Medical

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

## New Enterprise Associates
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 8
- Stages: Series B, Series A, Series C
- Focus: Software, Health Care, Biotechnology

New Enterprise Associates, Inc. is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors, and geographies. With over $19 billion in cumulative committed capital since the firm’s founding in 1977, NEA invests in technology and healthcare companies at all stages in a company’slifecycle, from the seed stage through IPO. The firm's long track record of successful investing includes more than 210 portfolio company IPOs and more than 360 acquisitions.

## Longwood Fund
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 8
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Longwood creates and invests in science-based companies that develop novel solutions for important medical problems

## Civilization Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 8
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

DIGITAL HEALTH / AI     
DIGITAL HEALTH / AI     GENE / CELL THERAPIES
NASDAQ: RCKT      GENE / CELL THERAPIES
NASDAQ: RCKT      GENOMICS / DIAGNOSTICS     GENOMICS / DIAGNOSTICS     
SYNTHETIC

## Vivo Capital
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 8
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Vivo Capital is a healthcare focused investment firm formed in 1996 that is currently making investments from its $1.4B Vivo Capital Fund IX into promising private healthcare companies and from its $635M Vivo Opportunity Fund into promising public healthcare companies.

## Google Ventures
- Type: VC Fund
- Location: Mountain View, California, United States
- Relevant deals: 8
- Stages: Series B, Series A, Seed
- Focus: Software, Health Care, Biotechnology

GV supports innovative founders moving the world forward.

## iSelect Fund
- Type: VC Fund
- Location: St Louis, Missouri, United States
- Relevant deals: 8
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Agriculture

Venture investing in Food, Health, and AgTech. A generational investment thesis. Food is Health is longevity

## Horizons Ventures
- Type: VC Fund
- Location: Hong Kong, Hong Kong Island, Hong Kong
- Relevant deals: 7
- Stages: Series A, Series B, Seed
- Focus: Biotechnology, Artificial Intelligence, Software

Investing in the deep science and technology that can propel humanity towards a radically better future.

## Apple Tree Partners
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 7
- Stages: Series A, Series B, Seed
- Focus: Biotechnology, Health Care, Therapeutics

ATP, a global leader in life sciences venture capital, is developing the next generation of transformative biotechnology companies. ATP creates science-based companies starting with assets at various stages: from working with scientists on pre-IP ideas, to spinouts from existing company pipelines. The firm provides flexible capital, strategicinsight, and operational resources to build sustainable, research-driven enterprises. ATP invests in its portfolio companies from seed stage through IPO and beyond and supports their management teams in strategic transactions and synergistic business combinations.

## Foresite Capital
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 7
- Stages: Series B, Series C, Series A
- Focus: Biotechnology, Health Care, Therapeutics

Foresite Capital is an investment firm that aims to transform healthcare by funding visionaries with the courage, data-driven insights and experience...

## Artis Ventures (AV)
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 7
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Software

Artis Ventures has spent over a decade backing bold teams who take the hard path, building market-defining companies to re-shape, re-invent, and re-make industries.

## Playground Global
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 7
- Stages: Series A, Seed, Series B
- Focus: Software, Robotics, Artificial Intelligence

Playground is an early-stage investment firm that helps old and new investors and entrepreneurs working at the intersection of bits, atoms, and AI. It focuses on investment, innovation, connected hardware, artificial intelligence, and robotics.

## Breakout Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 7
- Stages: Series B, Seed, Series A
- Focus: Biotechnology, Life Science, Therapeutics

Breakout Ventures is a new, early stage fund that backs bold scientist entrepreneurs working at the intersections of technology, biology, materials, and energy.

## Roche Venture Fund
- Type: VC Fund
- Location: Basel, Basel-Stadt, Switzerland
- Relevant deals: 7
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

The Roche Venture Fund is the name given to the corporate venture fund of the healthcare company Roche. Roche has allocated CHF 500 million to invest in and develop commercially successful innovative life science companies. Roche has been investing in early stage companies as part of collaborations since the early-1990s and independent ofcollaborations since 2002. All equity investments made by Roche in biotech and diagnostics companies (including collaboration investments) are negotiated and managed by the Roche Venture Fund. In the past 20 years, the Roche Venture Fund has invested in over 60 companies globally. Currently, Roche Venture Fund has a portfolio of around 30 companies located in 10 countries across Europe, North America and the Pacific Region. The fund is an evergreen fund with CHF 500 million available of which approximately 40% is currently invested.The Roche Venture Fund is a committed long-term stable investor with sufficient money reserved in their fund for follow-on financing rounds. As part of a multinational healthcare company, the Roche Venture Fund has access to considerable expertise both internally and externally. We co-invest with leading venture funds, including other corporate venture funds, on a regular basis.

## Connecticut Innovations
- Type: VC Fund
- Location: Rocky Hill, Connecticut, United States
- Relevant deals: 7
- Stages: Series A, Seed
- Focus: Health Care, Biotechnology, Software

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

## Flagship Pioneering
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 7
- Stages: Series B, Series C, Series A
- Focus: Biotechnology, Health Care, Medical

We create breakthroughs in human health and sustainability and build bioplatform companies .   Companies founded

## First Round Capital
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 6
- Stages: Seed, Series A, Series B
- Focus: Software, E-Commerce, Health Care

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

## Takeda Ventures
- Type: VC Fund
- Location: San Diego, California, United States
- Relevant deals: 6
- Stages: Series A, Series B
- Focus: Biotechnology, Health Care, Therapeutics

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

## Refactor Capital
- Type: VC Fund
- Location: Burlingame, California, United States
- Relevant deals: 6
- Stages: Seed, Series A, Series B
- Focus: Health Care, Biotechnology, Medical

Refactor Capital is an early-stage venture capital firm that invests in founders solving fundamental human problems.

## JDRF T1D Fund
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 6
- Stages: Series A, Series B
- Focus: Biotechnology, Health Care, Medical

The JDRF T1D Fund (www.t1dfund.org) is a venture philanthropy fund exclusively devoted to finding and funding the best early-stage T1D commercial opportunities to accelerate the delivery of treatments, preventions, and cures to patients. It was created to solve a critical funding gap in the T1D drug and device development pipeline. Throughpartnerships with private capital, including venture capital, pharma and foundations, the T1D Fund anticipates that it will be able to attract substantially more private investment to the T1D field than occurs today. The T1D Fund will initially focus on artificial pancreas systems, metabolic control, beta cell replacement, prevention, and beta cell restoration therapies, with an exclusive priority on the best commercial opportunities. The T1D Fund will reinvest any realized gains into new investments to further its mission.

## Boxer Capital
- Type: VC Fund
- Location: Windermere, Florida, United States
- Relevant deals: 6
- Stages: Series B, Series C, Post-IPO Equity
- Focus: Biotechnology, Health Care, Therapeutics

Boxer Capital, a private investment firm based in San Diego, California, invents and invests in biotechnology drug development companies across multiple therapeutic indications.

## Alumni Ventures
- Type: VC Fund
- Location: Manchester, New Hampshire, United States
- Relevant deals: 6
- Stages: Seed, Series A, Series B
- Focus: Software, Information Technology, Health Care

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

## Omega Funds
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 6
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

## Two Sigma Ventures
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 6
- Stages: Series A, Seed, Series B
- Focus: Software, Machine Learning, Artificial Intelligence

We are an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power to change the world.

## The Column Group
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 6
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

The Column Group is a leading venture capital firm dedicated to creating the next generation of biotechnology companies

## Dolby Family Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 6
- Stages: Series A, Seed, Series B
- Focus: Biotechnology, Health Care, Therapeutics

Dolby Family Ventures is an early stage venture firm focused on building great technology companies. They partner with best-in-class innovators and strong investment syndicate partners at the seed stage of a company’s development. Unlike many seed investors, They intend to continue to invest across future rounds in our successful portfoliocompanies.

## RiverVest
- Type: VC Fund
- Location: St Louis, Missouri, United States
- Relevant deals: 6
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Medical

RiverVest is a leading venture capital firm building life science companies to address significant unmet medical needs.

## Pear VC
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 6
- Stages: Seed, Series A, Pre-Seed
- Focus: Software, Health Care, E-Commerce

Pear VC partners with entrepreneurs from day zero to build category-defining companies.

## Felicis
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 6
- Stages: Series A, Seed, Series B
- Focus: Software, SaaS, Health Care

Backing founders building iconic companies that transcend boundaries

## Vida Ventures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 6
- Stages: Series A, Series B, Seed
- Focus: Biotechnology, Health Care, Therapeutics

Vida Ventures’ mission is to bring science to life by advancing transformative biomedical innovations that have the potential to make a meaningful impact on the lives of patients. They want to do well by doing good for others. Vida Ventures is a bicoastal life sciences company building and investment firm, founded in 2017 by a group of scientists,physicians, entrepreneurs, and investors who are passionate about building and funding breakthroughs in biomedicine .

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