# Top 50 Biotech Startup Investors in United States in October 2023

## ARCH Venture Partners
- Type: VC Fund
- Location: Chicago, Illinois, United States
- Relevant deals: 98
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

## Alexandria Venture Investments
- Type: VC Fund
- Location: Pasadena, California, United States
- Relevant deals: 75
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

## OrbiMed
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 67
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

## Innova Memphis
- Type: VC Fund
- Location: Memphis, Tennessee, United States
- Relevant deals: 63
- Stages: Seed, Pre-Seed, Convertible Note
- Focus: Health Care, Medical, Medical Device

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

## New Enterprise Associates
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 63
- Stages: Series B, Series A, Series C
- Focus: Software, Health Care, Biotechnology

New Enterprise Associates, Inc. is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors, and geographies. With over $19 billion in cumulative committed capital since the firm’s founding in 1977, NEA invests in technology and healthcare companies at all stages in a company’slifecycle, from the seed stage through IPO. The firm's long track record of successful investing includes more than 210 portfolio company IPOs and more than 360 acquisitions.

## 5AM Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 61
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries.
5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

## Atlas Venture
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 60
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

## MPM Capital
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 60
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Powering Breakthroughs in Life Sciences

## Versant Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 60
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Medical

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

## Third Rock Ventures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 55
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.

## Polaris Partners
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 54
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Medical

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

## Canaan Partners
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 50
- Stages: Series A, Series B, Series C
- Focus: Software, Biotechnology, Health Care

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

## BioAdvance
- Type: VC Fund
- Location: Philadelphia, Pennsylvania, United States
- Relevant deals: 49
- Stages: Seed, Series A
- Focus: Biotechnology, Health Care, Medical

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

## Khosla Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 48
- Stages: Series A, Series B, Seed
- Focus: Software, Health Care, Artificial Intelligence

Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.

## F-Prime Capital
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 46
- Stages: Series A, Series B, Series C
- Focus: Health Care, Biotechnology, Medical

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

## RA Capital Management
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 44
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

## Novartis Venture Fund
- Type: VC Fund
- Location: Basel, Basel-Stadt, Switzerland
- Relevant deals: 41
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Our primary focus is on the development of novel therapeutics and platforms. We balance the therapeutic focus with investments in medical devices, diagnostics or drug delivery systems. In our investments we look for unmet need and clinical impact, novel proprietary science and understanding of mechanism, management and board experience and capitalefficiency in the program.We prefer to have our initial investment at the early stage to build the company and follow with additional investment in pace with the company:tm:s progress. We continue our approach of larger focused investments and anticipate total investments up to USD 30 to 50 mio per company over its life, but it can be as little as 100'000 USD to get started. We will increase our activities to lead or co-lead deals further and remain open to participate in larger syndicates. SectorsNew therapeutics & platformsMedical devices/implantsDiagnostics/biomarkersDrug delivery/biopolymersGeographyUSA/CanadaEuropeSwitzerlandAsia/Pacific

## Frazier Healthcare Partners
- Type: VC Fund
- Location: Seattle, Washington, United States
- Relevant deals: 40
- Stages: Series B, Series A, Post-IPO Equity
- Focus: Biotechnology, Health Care, Therapeutics

Frazier Healthcare Partners: Investing exclusively in healthcare for 25 years.

## Connecticut Innovations
- Type: VC Fund
- Location: Rocky Hill, Connecticut, United States
- Relevant deals: 40
- Stages: Series A, Seed
- Focus: Health Care, Biotechnology, Software

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

## DCVC
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 38
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Health Care

We are deep tech venture capital.

## The Column Group
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 37
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

The Column Group is a leading venture capital firm dedicated to creating the next generation of biotechnology companies

## Fifty Years
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 37
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

WE BACK HEROES   using technology to solve the world's biggest problems

## Hatteras Venture Partners
- Type: VC Fund
- Location: Durham, North Carolina, United States
- Relevant deals: 37
- Stages: Series A, Series B
- Focus: Biotechnology, Health Care, Medical

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

## Andreessen Horowitz
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 37
- Stages: Series A, Series B, Seed
- Focus: Software, Information Technology, Internet

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

## Lux Capital
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 35
- Stages: Series A, Seed, Series B
- Focus: Software, Health Care, Biotechnology

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

## Boston Harbor Angels
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 35
- Stages: Angel, Seed, Series A
- Focus: Biotechnology, Health Care, Medical Device

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

## Northpond Ventures
- Type: VC Fund
- Location: Bethesda, Maryland, United States
- Relevant deals: 35
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Life Science

Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow. Our investments are focused on life sciences, technology, and affiliated industries.

## Amgen Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 33
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Amgen Ventures is a venture capital investment arm of Amgen Inc. specializing in investments in early and later stage companies. The firm primarily invests in the biotechnology sector with a focus on discovering and developing human therapeutics with a focus on oncology, inflammation, hematology, nephrology, metabolic disorders, neuroscience, andcardiovascular therapeutics. In oncology and hematology it focuses on novel therapeutics including signal transduction, cell cycle, and apoptosis; hematopoiesis including anemia, neutropenia, and stem cell mobilization; and supportive care including mucositis and cachexia. In nephrology the firm focuses on renal failure and hyperparathyroidism. For inflammation the firm focuses on rheumatoid arthritis, psoriasis, systemic lupus erythematosus, inflammatory bowel disease, multiple sclerosis, asthma and COPD, and osteoarthritis. Under cardiovascular, it focuses on acute coronary syndromes, dyslipidemia, and heart failure and under metabolic disorders it focuses on diabetes, metabolic syndrome, and osteoporosis. The focus on neuroscience included pain including neuropathic and inflammatory, alzheimer's disease, parkinson's disease, sleep disorder, cognition, and schizophrenia. In discovery research and technology the firm focuses on early-stage drug discovery collaborations, innovative chemical entity collections, diagnostics and biomarkers, novel antibody platforms, assay biologicals and devices, and target-focused structural biology and computational tools. It primarily invests in the North America, Europe, and the United Kingdom. The firm typically invests between $2 million and $3 million per transaction and may invest up to $10 million per company. It prefers to have an ownership stake of less than 15 % in its portfolio companies. Amgen Ventures was founded in 2004 and is based in San Francisco, California with additional offices in Seattle, Washington; Thousand Oaks, California; and Cambridge, Massachusetts.

## KdT Ventures
- Type: VC Fund
- Location: Austin, Texas, United States
- Relevant deals: 33
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Medical

KdT Ventures is the standard for early-stage frontier science investing.

## Sofinnova Investments
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 33
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Sofinnova deploys human and financial capital to turn dreams into drugs. We are a clinical-stage biopharmaceutical venture capital firm with approximately $2B in assets under management and committed capital.

## Google Ventures
- Type: VC Fund
- Location: Mountain View, California, United States
- Relevant deals: 33
- Stages: Series B, Series A, Seed
- Focus: Software, Health Care, Biotechnology

GV supports innovative founders moving the world forward.

## Life Science Angels
- Type: VC Fund
- Location: Sunnyvale, California, United States
- Relevant deals: 32
- Stages: Seed, Series A
- Focus: Biotechnology, Health Care, Medical

Life Science Angels, Inc. (LSA) is the premier angel investment group focused solely on healthcare investing, including medical devices, diagnostics, pharmaceuticals, biotechnology, and digital health.

## Domain Associates
- Type: VC Fund
- Location: San Diego, California, United States
- Relevant deals: 32
- Stages: Series B, Series C, Series A
- Focus: Biotechnology, Health Care, Medical

Founded in 1985, Domain Associates, L.L.C. is a venture capital firm with an exclusive focus on life sciences. With $2 billion of capital under management, Domain is headquartered in Princeton, NJ with a second office in San Diego, CA.Domain’s three major investment segments are pharmaceuticals, specialty pharmaceuticals, and medical devices,while additional areas of interest include biomaterials, bioinstrumentation, and diagnostics. The Partners of Domain have a total of close to 200 person-years of experience among them in the healthcare/venture capital industries and have been involved in the formation and growth of more than 200 life-sciences companies. The highly focused network, experience, and reputation of this team have made it one of the top private-equity groups participating in the healthcare field.

## Dolby Family Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 32
- Stages: Series A, Seed, Series B
- Focus: Biotechnology, Health Care, Therapeutics

Dolby Family Ventures is an early stage venture firm focused on building great technology companies. They partner with best-in-class innovators and strong investment syndicate partners at the seed stage of a company’s development. Unlike many seed investors, They intend to continue to invest across future rounds in our successful portfoliocompanies.

## Pfizer Venture Investments
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 32
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Pfizer Venture Investments is a corporate venture capital firm that invests in areas of current or future strategic interest to Pfizer. It aims to remain at the forefront of life science advances. It identifies and invests in emerging companies that are developing transformative medicines and technologies that have the potential to enhance Pfizer’spipeline and shape the future of its industry.

## Wisconsin Investment Partners
- Type: VC Fund
- Location: Madison, Wisconsin, United States
- Relevant deals: 31
- Stages: Seed, Series A
- Focus: Health Care, Biotechnology, Medical

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members.

## Takeda Ventures
- Type: VC Fund
- Location: San Diego, California, United States
- Relevant deals: 31
- Stages: Series A, Series B
- Focus: Biotechnology, Health Care, Therapeutics

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

## North Carolina Biotechnology Center
- Type: VC Fund
- Location: Alexander, North Carolina, United States
- Relevant deals: 30
- Stages: Debt Financing, Grant
- Focus: Biotechnology, Health Care, Medical

The North Carolina Biotechnology Center is a private, non-profit corporation funded by the N.C. General Assembly to strengthen biotechnology research, business and education statewide. The Center is not a site for laboratory research; it works to support job creation in the biotechnology industry.

## Refactor Capital
- Type: VC Fund
- Location: Burlingame, California, United States
- Relevant deals: 30
- Stages: Seed, Series A, Series B
- Focus: Health Care, Biotechnology, Medical

Refactor Capital is an early-stage venture capital firm that invests in founders solving fundamental human problems.

## Bay City Capital
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 29
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Bay City Capital LLC (Bay City Capital) was established in 1997 for the purpose of managing investment funds in the life sciences industry. Since that date, they have managed six venture funds representing $1.5 billion in capital invested in over 70 companies. Five of these funds are general life sciences funds, and one is a nutrition andagribusiness sector fund.

## HealthCare Ventures
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 29
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

HealthCare Ventures is a leading life science venture capital firm investing in pre-clinical or early clinical stage, focused companies with potential to transform patient care.

## Casdin Capital
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 29
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

Casdin Capital is a fundamental research investment firm focused on the life sciences and healthcare industry. It manages a long-short equity fund and makes investments in early-stage to late-stage private investments. Casdin was launched in 2012 by founder and CIO Eli Casdin and as of October 2020 has approximately $2.2 billion in assets undermanagement.

## Vivo Capital
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 29
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Pharmaceutical

Vivo Capital is a healthcare focused investment firm formed in 1996 that is currently making investments from its $1.4B Vivo Capital Fund IX into promising private healthcare companies and from its $635M Vivo Opportunity Fund into promising public healthcare companies.

## SR One
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 28
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Therapeutics

SR One Capital Management is a leading trans-Atlantic biotech venture capital firm that partners with top entrepreneurs, scientists and investment partners to seek to build elite biotechnology companies. Our mission is to translate ground-breaking technologies into next generation medicines to benef

## Alumni Ventures
- Type: VC Fund
- Location: Manchester, New Hampshire, United States
- Relevant deals: 28
- Stages: Seed, Series A, Series B
- Focus: Software, Information Technology, Health Care

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

## Novo Holdings
- Type: VC Fund
- Location: Hellerup, Hovedstaden, Denmark
- Relevant deals: 27
- Stages: Series A, Series B, Series C
- Focus: Biotechnology, Health Care, Medical

Novo Holdings is a world-leading life science investor with a focus on creating long-term value.

## Omega Funds
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 27
- Stages: Series B, Series A, Series C
- Focus: Biotechnology, Health Care, Therapeutics

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

## St. Louis Arch Angels
- Type: VC Fund
- Location: St Louis, Missouri, United States
- Relevant deals: 27
- Stages: Seed, Series A
- Focus: Biotechnology, Health Care, Software

The St. Louis Arch Angels is a network of accredited investors who fund early-stage businesses across the St. Louis region.

## Founders Fund
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 27
- Stages: Series A, Seed, Series B
- Focus: Software, Health Care, Internet

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

## iSelect Fund
- Type: VC Fund
- Location: St Louis, Missouri, United States
- Relevant deals: 27
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Agriculture

Venture investing in Food, Health, and AgTech. A generational investment thesis. Food is Health is longevity

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